UCSF study suggests novel factor could contribute to adult obesity
...he most dramatic results in the study. Young adult mutants spent their days scurrying back and forth to the feeder with a peripatetic urgency, yet despite their perpetual consumption they maintained normal body weight. It was only upon reaching middle age that they became obese. At nine to 10 months of age, ...Pavlov's flies: Researchers identify fruit fly memory mutants
...in brain neurons. The behavioral screen for memory mutants uncovered 60 genes, and the DNA chip analysis yiel...says Tully. "In fact, because our fruit fly memory mutants were found using a behavioral approach very similar to Pavlov's, our flies have come to be known as ...Mutants from a lowly weed may solve maladies
...cular genes work within the segments. That's where mutants help. Researchers can simply "knock out" a particu...plained. Koiwa already has located two Arabidopsis mutants for AtCPL genes, and different behavior of the two mutants implies that each have different function...Few microbiological differences in households using antibacterials
...e application site. Given that triclosan-resistant mutants of E. coli and Staphylococcus aureus have been isolated in the laboratory, concern has developed over the effect of home usage of residue-producing biocides on the microbiology of the home. Of particular interest is the possibility that prolonged app...Why have sex? The answer is not as simple as we thought
...eibler and Dr. Roy Kishony found that, on average, mutants fare better when they are stressed. "In contrast to the perception that stress always reduces the organism's ability to tolerate mutations, our measurements identified stresses that do the opposite that is, despite decreasing wild-type growth, on av...Purdue genetic discovery may aid plants and human medicine
... a bigger root system than in the wild type. These mutants are more resistant to wind and may be more robust in difficult environments where the soil is poor and the climate is arid. "Timing is also important," he said "If we can turn these genes on and off at the right times, we may be able to enhance a va...Scientists find what type of genes affect longevity
...ally disabling one gene at a time, either in daf-2 mutants or in wild-type worms, through a technique known a...her longevity genes found active in the long lived mutants make proteins that help ward off bacterial infections, the researchers found. Kenyon's lab showed ea...Researchers identify key molecular signal in plant pollination
...the machinery, the researchers are analyzing other mutants affecting pollen tube growth, as well as the reproductive metabolic changes in the tissues as they develop....Researchers identify molecular signaling system that is crucial for plant fertility
... said Preuss. The researchers are analyzing other mutants with altered pollen tube growth....New 'knockout' map helps study gene functions in model plant
...essential for understanding the function of genes mutants in which individual genes have been inactivated," says Parag Chitnis, program officer in the NSF's Division of Molecular and Cellular Biosciences. "Because the expression of hundreds of genes can change in a single condition, large complete collecti...Scientists at TSRI create new strain of yeast with 21-amino acid genetic code
...n so doing, they found their orthogonal synthetase mutants that load the orthogonal tRNA with only the desired unnatural amino acid. With this system, a ribosome that was reading an mRNA would insert the unusual amino acid when it encountered UAG. Furthermore, any codon in an mRNA that is switched to UAG wil...Leishmania mutant provides insight into disease and may lead to a vaccine
...ase in mammals. Compared to normal parasites, the mutants showed a 10-fold lower survival in the sand flies after three days, after which point they were completely eliminated. They also were unable to survive in macrophages. Next, the investigators injected the parasites into mice that were genetically su...Watching social behaviour evolve
...nhibited the evolved swarming phenotypes. Genetic mutants of the evolved strains were constructed that are u...en cultured alone on a plate, the fibril-deficient mutants swarm very poorly. When mixed as a minority with their adhesive, fibril-constructing parents, they s...Geneticists show ripple effects of gene mutations
... the Drosophila stock center and its collection of mutants and used a genetic method, pioneered by Mackay, called quantitative complementation tests. "Two-thirds of the genes within ripples resulting from the smell-impaired mutations themselves affected olfactory behavior. This means that the interactions th...Genes discovered that regulate blood stem cell development
... cells, and also had a tail defect. The zebrafish mutants generally die within seven to ten days after ferti...ox gene expression. When researchers injected the mutants with hox genes, such as hoxb7a and hoxa9a, it resulted in almost complete rescue of the deficient bl...Zebrafish studies provide insight into blood-cell formation
...rsely, injecting the normal cdx4 gene into kgg mutants "rescued" them from the defect. To see whether the cdx4 gene actually controlled hox genes, the researchers overexpressed various members of the hox gene family into the mutant zebrafish. The researchers found that some hox genes, but not oth...Purdue researchers solve decades-old corn, sorghum problem
...anism underlying the plant's mutation. These dwarf mutants are somewhat unusual, as their lower stalks are hi...een conclusively shown. "This finding in br2 dwarf mutants demonstrates the 'real-world' impact of research involving model plants," said Angus Murphy, assista...NSF awards four-year, $3.9 million grant to plant biology team led by University of Georgia
...e meristems. The lab uses specific leaf and embryo mutants of maize as the foundation to study these fundamental processes. Outreach and training will also be part of the grant, and undergraduate students from Truman State University in Kirksville, Mo., will engage in cutting-edge genomics research. Scanlon ...Proteins enable HIV to override cell's defenses
...IV infectiousness was reduced 90 percent when Cul5 mutants were over expressed in combination with APOBEC3G. Dr. Yu and his collaborators, Drs. Xianghui Yu, Yunkai Yu, Bindong Liu and Kun Luo, are working on further explaining the mechanism of Vif and Cul5 complex interaction and identifying strategies to b......st clearinghouse of prized Drosophila mutants. The mutants are crucial to scientists' experiments in many fields including genetics, molecular biology, cell biology, developmental biology and evolutionary biology. Kaufman estimated the center currently sends out about 2,000 strains a week from the stock cent...