Tag: "myc" at biology news
Researchers Find How Two Cancer Genes Interact To Cause Malignancy
...wth-promoting abilities. Ifras is not mutated, the myc
growth-stimulating signal dies rapidly and cellula...e. "In the mid 1980sscientists showed that if both myc
and ras were mutated, the cells becamecancerous. Until now there has been little mechanistic informa...
Genes Found That Label Cell Proteins For Disposal
...he explains. Another example is the cancer-related myc
(pronounced MIK) oncogene and theprotein it trans...teins, too high in the case of oncoproteins suchas myc
or cyclin D or too low in the case of tumor suppressor proteins such asp53, have one common conseque...
American Association for Cancer Research honors Fred Hutchinson Cancer Research Center investigator
...se cancer. His research regarding a gene known as myc
has been key to understanding how normal cells become cancerous, said Mark Groudine, M.D., Ph.D., director of the Basic Sciences Division. "Bob has contributed the most innovative, insightful and reliable work in the field," he said.In addition to ca...
Scientists discover role for c-myc gene in tumor angiogenesis
...al target to anti-angiogenic cancer therapies. The myc
family of oncogenes (c-myc, N-myc, and L-myc) function in the control of cell proliferation, differentiation, and tumorigenesis. Although it has long been recognized that c-Myc's positive effect on cell proliferation can contribute to cancer developm...
...rosophila and human genomes, respectively. As the myc
gene is mutated in approximately one-third of all ...ns will be important to understanding how abnormal myc
expression can lead to cancer. The myc
gene encodes a transcription factor (Myc) that, together with...