The search for a kinder, gentler chemotherapy
...he nanoparticles. "The possibility for using these nanoparticles as vehicles to target and kill only cancer cells is particularly exciting," said Jean Chmielewski, professor of chemistry at Purdue University. "Decorating the exterior of the vehicle with folic acid is a very direct route to enter cancer cells. This...Story tips from the Department of Energy's Oak Ridge National Laboratory, September 2004
...hotosensitive materials, ORNL researchers produced nanoparticles with superior optical and electronic "quantum dot" properties that function similarly to light-emitting diodes or transistors. The versatility introduced by the use of organic polymers could result in such future products as electronic paper, lumines...New imaging technology at Joslin shown to detect early signs of type 1 diabetes
...mmonly known as MRI, to monitor miniscule magnetic nanoparticles leaking from the blood vessels of the pancreas, ac... probes called long-circulating magnetofluorescent nanoparticles (CMFN). These particles contain magnetic nanocrystals of iron oxide, which are very easily detected...Professor calls for a new branch of learning
...potential threats to health that widespread use of nanoparticles could bring need to be scrutinised, says a Univers...d that a focus on the potential harmful effects of nanoparticles is both timely and necessary. The importance of nanotechnology to the economy and to our future well...Trojan Horses, xenon imaging and remote controlled genes
...nts for drug delivery, templates for forming metal nanoparticles and chemical probes for use in in vivo spectroscopic studies. A Light Switch for Turning Off Genes In order to understand the role of certain genes in embryonic development, the Dmochowski lab is studying how to use light to turn genes off....Researchers show how to assemble building blocks for nanotechnology
...researchers have discovered a way to self-assemble nanoparticles into wires, sheets, shells and other unusual structures using sticky patches that make the particles group themselves together in programmed ways. This method could be used to fabricate new materials and devices for nanotechnology. Using computer sim...RNA could form building blocks for nanomachines
...pulating controllable structures of this size from nanoparticles is one of nanotechnology's main goals. "Our work shows that we can control the construction of three-dimensional arrays made from RNA blocks of different shapes and sizes," said Peixuan Guo, who is a professor of molecular virology in Purdue's Sc...Ancient life form may help create newest technologies
...lding blocks of these materials are referred to as nanoparticles because they are extraordinarily small clusters of several hundred molecules less than 100 nanometers in size - compared to a human hair that is 20,000 nanometers wide. "Procedures exist to produce germanium nanocomposites, but they are fairly inef...Newly designed nanoparticle quantum dots simultaneously target and image prostate tumors in mice
...time used a new class of luminescent "quantum dot" nanoparticles in living animals to simultaneously target and image cancerous tumors. The quantum dots were encapsulated in a highly protective polymer coating and attached to a monoclonal antibody that guided them to prostate tumor sites in living mice, where the...ORNL nanoprobe creates world of new possibilities
...g 100 nanometers with an extremely thin coating of nanoparticles of silver, which induces the surface-enhanced Raman scattering (SERS) effect. Normally, when a sample is illuminated by a laser beam, there is a small reflection of light, known as Raman scattering. The light shows vibration energies, which are uniqu...Nanosphere announces genetic detection advance in Nature Biotechnology
...nts." At the core of Nanosphere's technology, gold nanoparticles are attached to strands of nucleotides complementary to targets of interest, and when a target nucleic acid or protein is present, the nanoparticle probes latch on to the match and provide a strong optical signal indicating the target has been found....Nanoparticles illuminate brain tumors for days under MRI
...s. "This is one of the first biologically specific nanoparticles to be used in clinical trials," said Neuwelt, dire... Dotter Interventional Institute, OHSU, agreed the nanoparticles show potential for providing insight into a variety of brain pathologies. "We're learning that disea...Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
...e Mayo Clinic found they could isolate and culture nanoparticles from filtered homogenates of diseased calcified hu...ter-sized particles which share characteristics of nanoparticles recovered from geological specimens, mammalian blood, and human kidney stones, and observed by trans......oglu, however, insisted that they had observed the nanoparticles self-replicating in a culture medium and claimed t...sked. Cisar has an answer to this. After studying nanoparticles found in saliva, his team published a paper in 2000 claiming that the DNA detected by the Finnish te...Protein-centric drug development and functional glycomics enrich biopharmaceuticals pipeline
...tment. However, dealing with the toxicity of trace nanoparticles that could be left behind in the body, is a major concern. Another promising technique is nano-sized dendrimers that escape the blood stream through vascular pores, and selectively target and treat tumor cells. Dendrimer-based drugs coupled...UCLA chemists develop new coating for nanoscale probes
...es, and trick the live cell into thinking that the nanoparticles are benign, protein-like entities," said Shimon We...f toxic-free ions by strongly binding to inorganic nanoparticles made of the sequestered toxic salts and other products. "Our peptide coating bridges the inorg...Researchers probe link between nanotechnology and health
...dical applications under development include using nanoparticles as drug-delivery systems, or as a super-advanced t... a hypothesis that the chemical characteristics of nanoparticles determine how they will ultimately interact with human or animal cells. A negative cellular response...Nanotechnology highlights from the ACS national meeting in Anaheim, Calif., March 28-April 1
...ifornia Pavilion D.) Monday, March 29 Tiny iron nanoparticles show promise for cleaning up big industrial sites ...s have developed a method to make inexpensive iron nanoparticles that exceed conventional methods in efficiency and speed, cleaning up sites in a matter of weeks. Th...Methuselah enzymes: SEN and the art of molecule maintenance
...ng free enzymes into these novel enzyme-containing nanoparticles can result in significantly more stable catalytic activity," added Jay Grate, PNNL laboratory fellow and SENs co-inventor. Kim and Grate, working in the W.R. Wiley Environmental Molecular Sciences Laboratory at PNNL, modified a common protein-spli...NJIT chemists pave way for cheap, usable field test for polluted, toxic, water, air, food
Such nanoparticles abound now as trace chemicals in polluted air or w... The name of the presentation is "Self-Assembly of nanoparticles For Preconcentration in Environmental Sensing Platforms." (Editors and reporters may call Sheryl We...