'Dissecting sleep' by studying the strange phenomenon of cataplexy
...ffer insight into the basic molecular mechanism of narcolepsy and cataplexy. Humans with narcolepsy have reduced numbers of neurons that release small proteins called hypocretins, and it is the effect...UT Southwestern research halts narcolepsy symptoms
...e the chemical on their own rids the mice of their narcolepsy symptoms, UT Southwestern researchers have discove...ce. Dr. Yanagisawa said any new drug therapies for narcolepsy would be based on developing molecules, called orexin receptor agonists, that mimic the effect of or.......001) in familial cases of SW. Thus, together with narcolepsy and REM sleep behavior disorder, these findings suggest that specific DQB1 genes are implicated in disorders of motor control during sleep. These finding represents the first genetic marker for SW. Citation source: Molecular Psychiatry 2003 Volume 8,...Emory School of Medicine teams with deCODE Genetics to study link between genes and disease
...ease, and Dr. Rye has joint studies with deCODE on narcolepsy and restless legs syndrome. "Many neurological diseases result from a complex mixture of environmental and genetic causes," Dr. Levey explains, "and although we have learned about genes that are responsible for a small percentage of cases of Alzheim...Sleeping dogs lend a paw to narcoleptics
...ch canines are helping scientists understand human narcolepsy and sleep control. In the April issue of Genome R...lepsy. Previous studies suggest varying causes for narcolepsy in humans and dogs, but recent work strongly implicates the hypocretin system, a network of brain ce...UT Southwestern researchers create mice with narcolepsy
...asleep at inappropriate times. Knowing what causes narcolepsy could lead totreatments. The research will...(NREM). People and animals not affected by narcolepsy usually have about an hourand a half of NREM before entering the REM stage, which is a deep sleep an......ondition similarto narcolepsy. In humans, signs of narcolepsy usually begin during a person'steens or early 20s....andquickly falls into deep sleep. Some people with narcolepsy experience vividdreams; others describe a sense of paralysis. On occasion, narcolepsy isaccompanied ...... and Blood Iinstitute on discovery of the gene for narcolepsy in dogs The discovery of the gene for narcolepsy in dogs by Dr. Emmanuel Mignotand his group at Stanford University School of Medicine has particular...