ORNL Microscope "Sees" Bumps That Reveal Partial DNA Structure
...g the surface of a material, similar tothe arm and needle of a phonograph playing a record. The research, which was performed for the Human Genome Project, was fundedby the Department of Energy's Office of Health and Environmental Research.Continued research on the binding of transcription factors is beings...New Sensor Will Detech Chemical And Biological Pathogens At Incredibly Small Doses
...members, isnow capable of literally identifying "a needle in a haystack," says WilliamVelander, one of the inventors. His device has showed results that are 20 timesmore powerful than previous sensing devices. Velander, a biochemical engineer who heads Virginia Tech's Pharmaceutical EngineeringInstitute, t...Jefferson Scientists Devise Way To Treat Animals Chronically Infected With Hepatitis B
...ted sexually. It is also transmitted by accidental needle sticks amonghealth care workers. Some one-quarter to one-third of the population that ischronically infected have no known risk factors. Those at risk for contracting HCV include intravenous drug abusers, andthose who had transfusions prior t...Taking The "Ouch" Out Of Needles: Arrays Of "Microneedles" Offer New Technique For Drug Delivery
...g drugs through the skin,providing the benefits of needle injection without the disadvantages ofconventional...e local inflammation, or if the body reacts to the needle materialitself. Using existing silicon material, the tips of a very small number of theneedles can ......nical stimulation of the cells using a tungsten needle of the same diameter as a fungal hypha (2-5 m). As with the fungal infection hypha, by itself this local mechanical stimulus induced the translocation of cytoplasm and nucleus to the site of stimulation. Interestingly, some of the biochem...The Best Molecular Snapshot Yet Of Cells Affected By Alzheimer's Disease
... in the spinal fluid, but that's likelooking for a needle in a haystack," says Zaven Khachaturian,director of the Alzheimer Association's Ronald and Nancy ReaganInstitute and former director of Alzheimer's disease research atthe National Institutes of Health. "The Rochester team is able tofocus in on cells ...Blindness Linked To The Cytoskeleton?
...ne product. The challenge was to find the needle of 3,800 base pairs (which represents the protein coding portion of the RP2 gene) in a haystack of 4,000,000 base pairs of X-chromosomal DNA where, according to data from family studies, the RP2 gene must be located. In order to get a......o, a hollow ball of about sixty four cells, with a needle a fraction of thewidth of a hair, and injects cells lacking a specific gene into the blastula. These blastulas are then surgically introduced into female mice that serve assurrogate mothers. Some of the offspring born two and one-half weeks l...Spider Venom Stops Stroke Brain Damage
...neuroactive chemical, Meinwald said, "Looking fora needle in a haystack is easier. There you just get a big magnet and you'llfind it. Looking for this chemical, we didn't know what we'd find. We didn'tknow what kind of structure we were looking for." HF-7 works in the brain by blocking one in a family o...Genetic Research Boosts Understanding Of Iron's Path Through Body, Diseases Of Iron Metabolism
...gh cheap andeffective, most patients hate having a needle stuck in their arms every month,Andrews says. Ultimately, knowing the molecular biology underlying this andother iron diseases may lead to more modern treatments This study was funded in part by the NIH. First author Joanne Levy, OuJin, and Y...Aging Vehicle Fleet Polluting The Air
...failed an emissions test. "It's like looking for a needle ina haystack," Rodgers says. But the search is worth it because of theirsignificant contribution to air pollution. Researchers in the Air Quality Laboratory regularly conduct remotesensing and roadway studies along the metro Atlanta area's in...Mouse Map Leads Way To Human Disease Exploration
... 1% of the gene. It really starts to pinpoint that needle in ahaystack," said Dr. Korenberg. The study also tracks the beginnings and endings of strings of mousechromosomes, so that scientists hunting for a particular "address" within thegenome will have a better neighborhood map within which they can focus...On the floor of the sea: USGS biologists search for rare, white abalone
...arvesting made the abalone asdifficult to locate a needle in an ocean-sized haystack. "People thought it was impossible to take such a fecund animal - a single femalecan produce 10 million eggs in a season - and drive it to extinction throughfishing," said Gary Davis, a senior scientist at the Channel Islan...Penny wise and pound-foolish: Study shows need for second pathologist's opinion
... he explains, may be advances in technology -- the needle biopsies, PSAs and improved radiology made to nip ...t larger samples of tissue to evaluate; now we get needle biopsies of brain, breast, lymph nodes and prostate glands. That's good for patient recovery from t...Test provides accurate, noninvasive method to determine fetal lung development, UF researchers find
...he fluid via amniocentesis, a procedure in which a needle is inserted through the abdominal wall into the ut... than normal inside the uterus, the target for the needle is smaller -- increasing somewhat the risk of fetal injury. The UF study evaluated the TDx/TDxFLx ...ASU scientists probe salamander mysteries
...intment, they found nothing. "You're looking for a needle in a haystack," warned the skeptical microscopist who assisted them. "That day we went home bummed," says Jancovich. "But we came back on Monday morning and looked at each other and we both said we're going to find this thing.' We looked in an insec...Hopkins researchers develop a non-invasive screening test for cancer
... mutations in bodily fluids was like looking for a needle in a haystack," says Sidransky. "Finding mitochondrial mutations is much easier. With additional research, we expect to be able to identify mitochondrial mutations through a simple blood test," he says. Until now, most cancer-related genetic mutatio......on neurons implanted at three sites along a single needle pass within the basal ganglia. The remaining eigh...ed to receive either two million neurons along one needle pass or a total of six million neurons implanted along three trajectories. Assessment of safet...Bone produced from skin and gum tissue
...lve harvesting a patient's bone marrow with a long needle or surgically removing a piece of bone, typically from the hip. With the new method, which is still in developmental stages, a tiny bit of skin or gum tissue is removed, cut into even smaller pieces, and placed in a culture dish. The cultured cells...Cincinnati researchers document environmental problems caused by tourist trade in Crete
...p a syringe from a pile of refuse."It even has the needle on it." A nearby illegal moto-cross training field creates noise that has scared away the migratory birds that once stopped here on their way to and from Africa and Europe each year, according to local residents. British birdwatchers who once freque...