New drug boosts fight against HIV, researchers find
...ssentially two protease inhibitors in one) against nelfinavir (the most common protease inhibitor used in Canada...evidence of resistance to the drug compared to the nelfinavir group, in which 33 per cent of failing patients developed resistance. "Two main barriers to treatmen...48-wk resistance data comparing GW433908 boosted & unboosted with nelfinavir
...r (908/r) dosed once a day (QD) compared to the PI nelfinavir (NFV) BID. The medications in both studies were ... percent) who experienced virologic failure in the nelfinavir arm. In the NEAT study, mutations selected by 908 were consistent with the spectrum of mutations sel...24-Wk data from CONTEXT trial comparing GW433908/ritonavir QD & BID to Lopinavir/ritonavir BID
...908 plus 200 mg ritonavir (908/r) QD or 1250 mg of nelfinavir BID. All also received the two NRTIs, ABC and 3TC...llel-group 48-week study that compared 908 BID and nelfinavir BID, both in combination with ABC and 3TC in 249 antiretroviral therapy-nave patients. The primary ...Phase III, 48-Wk NEAT study results comparing GW433908 to Nelfinavir presented today
...n antiretroviral therapy-nave HIV+ patients versus nelfinavir (NFV/Viracept), were presented here today. In the...of 908 (2 tablets) twice daily (BID) or 1250 mg of nelfinavir (5 tablets) BID. 908 was taken without food or fluid restrictions. Both groups took these medicati...