Brain Protein "Rescues" Neurons From Atrophy
...functional patterns as a result of experience. The new studies, however, show that the neurotrophins are ...vier use translates into stronger connections. The new study indicates that neurotrophins -- which are released from neurons when they are triggered to fir...Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...way from the hemes. Specifically, in its new form, this NO is attached to a thiol and is calledSNO (for S-nitrosothiols). SNO retains its NO-like properties, but is "asouped-up cousin," Stamler said. SNO is protected from inactivationby hemes, unlike NO produced in vessel walls, and it has a wi...... may provide the first realistic model for testing new treatmentsfor psychiatric disorders. "We were ast...buse (NIDA). "Thisfinding provides a fundamentally new scientific tool in the arsenal to understandand ultimately break the addictive power of drugs." Car...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
..., Dr. Wang is hopeful that this relatively new approach to drug design will yield results. "Structure-based design is still in its infancy, so there are people who are skeptical about it," Dr. Wang said. "My own bet is that this kind of work will get bet...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
DURHAM, N.C. -- A new way that cancers may be triggered in the body -- t...in October and November, all of which point toward new ways to interfere with the malignant machinery of cancer cells to kill them. In a second paper in th...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
... as Huntington's disease, as well as discovering a new conceptof how mutant genes may produce disease. T... brain. The work offers biomedical researchers a new way to understand, and to potentiallytreat these genetic diseases, the Duke scientists say. "This ...Researchers Pinpoint Site For Petit Mal Seizures In Brain
... University Medical Center reported Monday finding new clues about the precise location in the brain that... mice genetically prone to petit mal epilepsy. The new information will allow the research team to pinpoint the exact mechanism by which GABAb receptors ca...Tumor Suppressor Gene Located In Liver Cancer Cells
... early diagnostic test for liver cancer as well as new treatments, the researchers said. The disease is... gene for which we have characterized an important new role," Jirtle said. When working properly, the M6P/IGF2r receptor protein has at least three distinc...New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
... The finding suggests the possibility of a new kind of antibiotic that couldrecognize the unusual...d helical structure may offera unique target for a new generation of antibiotics designed to home inon the structure. The left-handed structure also offers...Duke Geologists Explore Alternative Way To Measure Ice Age Sea Bottom Temperatures
DURHAM, N.C. --A new study suggests that differing calcium-magnesium ra...nd interglacial intervals. "We wanted to take this new technique somewhere where we knew there was a temperature change, so we would be likely to see somet......neering geochronologist Richard Teh-Lung Ku, whose new analysis of one of the most important finds in hum...lped develop the sophisticated methods used in the new analysis. The two scientists' preliminary findings will appear as a lead article in the August 1996 ...Computer Program For Quicker, More Detailed Mapping
...nford Human Genome Center have developeda powerful new computer program that can map thousands of genetic...Myers. "Now we can rebuild it every day, including new informationas it is gathered. Our maps are now much more accurate because we can mapeverything at on...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...ckshear said."This finding provides insight into a new gene that appears to regulateTNFa. It is possible ...people. "The TTP-deficient mouse is an exciting new model of arthritis,"said Haynes, chairman of medicine at Duke and director of the Duke UniversityArt...From Corn Rootworms To Art, Cornell's Reactor Is At The Core
... penetrate the lead box. "Neutron radiography is a new way of looking at things and has proved to be a ve... It's extremely useful." Now he is embarking on a new project, in collaboration with the Getty Conservation Institute in California, to try to resurrect a...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
... in the June issue of Nature Medicine ,opens up a new realm of possibilities for correcting genetic information,according to Bruce Sullenger, assistant professor of experimental surgeryand genetics. The Duke team already has begun exploring use of these newtherapeutic approaches for sickle cell anemia a...New Discovery About Genes Has Implications For Genetic Therapy
...mation -- may well be the key to determining where new information is transferred into a gene. If true...ng genetic therapy. Current techniques can insert new information into genes but exactly where that information is transferred is often left to chance. ...Mutate Or Die: New Polymerase Gives Desperate Yeast An Option
Biologists have discovered the first of a new DNA polymerase family: a last-gasp enzyme that yea... June 14 issue of Science . The findings shed new light on how yeast and probably other organisms cope with damaged DNA, a constant,potentially danger...International Research Team Clones New Skin Cancer Gene
... each year, and its incidence is on the rise. The new gene, called PTC, is essential for keeping skin cells under control. "Genetic mutation of PTC is the key step in development of skin cancer,2 said Allen Bale, M.D., senior author of the Cell paper and director of the Cancer Genetics Program at the Y...Cornell Researchers Precisely Date Wood From Ancient Tomb In Turkey
...tless works of classical literature and film. The new chronology also has implications for historical ac...s from Assyria and Syria," the authors write, "the new fixed dendrochronology provides important evidence towards the resolution of a century of debate ove......nutrition sciences. Houtkooper has developed this new training program over several years withmany of the women heptathletes. The most important key to an athlete'ssuccess, said Houtkooper, is replacing fluids lost during practice andcompetition. She adds that this is especially critical in the hot and ...