New study shows hope for treating inhalant abuse
...n seen in Brookhaven's earlier studies of GVG with nicotine and heroin. "The findings of this study extend the potential value of GVG to treat addiction," says Stephen Dewey, the Brookhaven Lab neuroanatomist who led the study. "More importantly, our results show promise in treating inhalant abuse as it ...Cutting back on cigarettes: when less is more
...sting their consumption of smoke, carbon monoxide, nicotine and other cancer-causing agents. The findings hold...tinine, a metabolite of nicotine, reveals how much nicotine has been absorbed over time. The scientists also carefully observed the way the women smoked scient...Prenatal nicotine primes adolescent brain for addiction
DURHAM, N.C. -- Prenatal exposure to nicotine inflicts lasting damage that might leave the brain...ts. The team found in rat studies that exposure to nicotine in fetal development alters the brain structures and brain cell activity in regions critical to lear...Nicotine exposure in aging hearts
...ans still smoke cigarettes or use over-the-counter nicotine products such as patches and gums to satisfy their...tion (AF) have been reported in patients who use a nicotine product. This is particularly true when the individual has smoked while using a nicotine patch. AF i...An apple a day keeps the doctor away . . . but so may a cigarette
... unlocked one of the first doors, discovering that nicotine repairs damaged brain function. Karim Alkadhi, as...College of Pharmacy recently have established that nicotine has a beneficial effect and, in many cases, even repairs memory impairment caused by stress on the b...JAK2 enzyme helps protect brain cells, wreaks havoc on blood vessels
...lls are exposed to beta amyloid that makes plaque, nicotine protects them by activating JAK2, which activates ... and a growth factor as well is added to the mix, nicotine no longer protects brain cells. "Angiotensin II doesn't allow JAK2 to be activated by nicotine," Dr...Staph aureus bacteremia in ESRD patients associated with substantial illness and higher costs
...ions, immune thrombocytopenia purpura ("ITP"), and nicotine addiction. Nabi Biopharmaceuticals has several products in clinical trials, as well as five marketed products, including Nabi-HB [Hepatitis B Immune Globulin (Human)], for the prevention of hepatitis B infections upon acute exposure; WinRho SDF [Rho...DFG presents the new MAK and BAT Value List 2003
...irmed for five more working substances, among them nicotine and tetrahydrofuran. There are five new entries and changes in the section "BAT values, biological guideline values and exposure equivalents for carcinogens" ("BAT-Werte, BLW und EKA"). Apart from lowering the BAT value for lead for women under 45 ye...OHSU researcher publishes first measurements of 'free-base' nicotine in cigarette smoke
PORTLAND, Ore. -- When it comes to nicotine content, all cigarettes are not created equal, acc...rands contain 10 to 20 times higher percentages of nicotine in the so-called "free-base" form -- the form thought to be most addictive -- than believed up to no...Cigarette smoke linked to low folate levels
...and older who received blood tests for cotinine, a nicotine byproduct, and folate. The people were also asked about their eating and smoking habits. Older individuals in study, those ages 50 and older, were less likely to be active smokers or to be exposed to high levels of secondhand smoke. The researchers m...Chronic alcohol abuse damages regulating hormones
...ed on cigarette use. "It is well known that acute nicotine increases the secretion of AVP," explained Ehrenreich. "It has to be assumed that chronic cigarette consumption also alters AVP secretion or metabolism. Therefore, we used cigarette-matched controls in order to exclude the influence of such an inte...Prenatal exposure to nicotine increases risk of apnea in brains of newborn rats
...a researchers report new evidence that exposure to nicotine in the developing rat fetus enhances the function ...tudies by other investigators showed that prenatal nicotine exposure enhances the function and density of GABAa receptors in the cortex, hippocampus and other a...Underwater sensor system could protect reservoirs, drinking water
...antibiotics, estrogen-type hormones, insecticides, nicotine and other chemicals in the rivers of industrialized countries," says Dr. Craig A. Grimes, associate professor of electrical engineering and materials science and engineering. "However, analysis is still done by physically collecting samples and anal...... increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area" S R Laviolette and ...icotine. They demonstrate that direct infusions of nicotine into the VTA can produce both rewarding and aversive motivational effects. While the rewarding effec...JCI Table of Contents, January 2, 2003
...on the packs, scientists had initially assumedthat nicotine was the addictive agent, and tar the carcinogen. R...rInstitute in Bethesda, have studied the effect of nicotine and thenicotine-derived nitrosamine NKK on normal lung epithelial cells--i.e. thosecells that are ex...USF study: Nicotine antagonist relieves depression in children with Tourette's
...ec. 10, 2002) -- A well-tolerated drug that blocks nicotine receptors in the brain appears to relieve depressi...larger clinical studies are needed to determine if nicotine antagonists like mecamylamine would provide a new avenue for treating depression and other mood diso...Beyond patches and pills: the remarkable future of drug delivery
... these years have seen impressive advances -- from nicotine patches to nasal inhalers -- the most promising technologies still lie ahead. This burgeoning area of research could someday produce an insulin pill for diabetics, an under-skin pharmacy on a microchip, and even lab-grown organs for transplants and p...Gene researchers close in on nicotine's 'evil cousin'
...se health-conscious times. As a chemical compound, nicotine even has beneficial properties. It's used around t...ar misconceptions - it is not a carcinogen. Take a nicotine molecule and snip off a methyl group, though, and you've got nicotine's evil cousin: nornicotine. (A...Exploring the genetic commonality of alcohol and tobacco abuse
... involved in modulating sensitivity to alcohol and nicotine and this, in turn, influenced the development of t...ntrol (CAS) sensitivity to alcohol were tested for nicotine sensitivity using several different measures. The HAS rodents were found to be more sensitive to on...Nabi Biopharmaceuticals begins human testing of novel vaccine to fight nicotine addiction
...d to help the body develop antibodies that bind to nicotine and block it from reaching the brain. If shown to...n entirely new approach to fighting and preventing nicotine addiction," said David J. Gury, Nabi Biopharmaceuticals chairman, president and chief executive offi...