New predictor of heart disease risk found
...This protector enzyme, called eNOS, or endothelial nitric oxide synthase, produces nitric oxide, which works to keep blood vessels healthy and heart disease at bay by preventing plaques from...Genetic variant protects people against malaria
...sm" in the NOS2 gene -- controls the production of nitric oxide, a small chemical that can kill parasites an...e with the NOS2 gene variant make higher levels of nitric oxide, and the nitric oxide protects them from the extensive tissue and brain damage normally caused...JCI Table of Contents, December 2, 2002
...Rapid nontranscriptional activation of endothelial nitric oxide synthasemediates increased cerebral blood fl...of PI3K and Akt. This inturn activates endothelial nitric oxide synthase, thereby increasingcerebral blood flow by 4050% and reducing cerebral infarct size by...JCI table of contents, January 15 2003
....pdf Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependentactivation of soluble guanylyl cycl.../16672.pdf ACCOMPANYING COMMENTARY: A role for nitric oxide in hydroxyurea-mediated fetal hemoglobin induction CONTACT: Bruce King Wake Forest University...For spinal cord injury patients, new insights for rehabilitation therapy
...ominance of endothelin-1 release and a decrease in nitric oxide release; (2) after deconditioning of the leg muscles, oxygen demand will be low, and oxygen delivery will be geared accordingly, which would lead, most likely via flow-dependent mechanisms, to vascular atrophy; and (3) in long-term SCI patients...Stanford researchers identify genes involved in tuberculosis latency
...tion of low oxygen levels and increased amounts of nitric oxide - a molecule secreted by activated immune ce...ribute to long-term persistence. Falling levels of nitric oxide, often a hallmark of an immune system weakened by disease or age, coupled with robust oxygenat...Meeting the nitrogen management challenge: Arresting the nitrogen cascade
...ting reactive nitrogen. Ammonia, nitrous oxide, or nitric oxide volatilized to the air, produced by the reactive nitrogen, cascades through environmental reservoirs in the atmosphere, terrestrial ecosystems, and aquatic ecosystems. The nitrite can make surface and subsurface waters unsuitable for humans, ...New potential therapy for sickle cell disease
...riguing preliminary evidence that inhaling the gas nitric oxide may relieve the vaso-occlusive pain crises s...JAMA, this is the first published study of inhaled nitric oxide for treatment of these intensely painful, debilitating episodes in children. Pain crises ofte...Boulder chemist wins national award for studies of atmosphere
...o balloons and measure chemicals such as ozone and nitric oxide. Interestingly, a nitric oxide monitor may have medical benefit as well. The gas's presence in human breath is a signal for t...Experimental Biology 2003 meets in San Diego April 11-15
... negative effects of the body's high reactivity to nitric oxide. Other examples of APS presentations include transgenic models of heart failure therapeutics, physiology of high altitude decompression sickness, and why brain remodeling underlies the success of behavioral therapies for motor dysfunction. T...Common Indian spice pigment can prevent onset of alcoholic liver disease, study finds
...ory protein-2, cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nitrotyrosine. Results In each of the four groups, the rats increased their weight at a constant rate. Moreover, there was no difference in weight gain among the groups. There was also no difference in levels of blood alc...Novel COX-2 combination treatment may reduce colon cancer risk
...COX-2 expression and activity, and iNOS (inducible nitric oxide synthesis) expression. Results showed that celecoxib and/ or DHA inhibit cell growth and induce cell death at concentrations of >100 M (micrometer) celecoxib and >150 M DHA in the human colon cancer cell line HCA-7. However, combinin...A cholesterol-controlling drug could strike a blow against insulin resistance
...t decade, evidence has accumulated indicating that nitric oxide (NO) may play a key role in the control of m...evidenced by mice lacking the gene for endothelial nitric oxide synthase (eNOS) that are insulin resistant and hypertensive. An animal study now finds that st...Could hibernators hold the key to improving organ preservation?
...quirrels. Ground squirrels have higher levels of nitric oxide synthase (NOS) in their livers when they are...cause NOS activity produces the chemical messenger nitric oxide, which is a potent vasodilator. Specialized immune cells in the liver -- known as Kupffer ce...Tufts University biologists unveil more mysteries of fireflies flash
...g." Lewis' previous research on how fireflies use nitric oxide to turn their flashes on and off was published in the June 2001 issue of Science....Nitric oxide-like drug could revive a failing heart
...ted with nitroglycerin or other drugs that release nitric oxide into the bloodstream. While these medicines...s researchers suggests that a chemical relative of nitric oxide could better restore normal function to failing hearts. Studying normal dogs and those with he...Critical early-defense trigger in plants found
...by a pathogen. When activated, the enzyme produces nitric oxide (NO), a hormone that tells the plant to turn...mselves from disease. "It's known that the hormone nitric oxide plays an important role in immunity in plants as well as in humans and other animals," says Kl...Nitric oxide has important role in fever regulation, new study says
...e of the Journal of Applied Physiology, shows that nitric oxide does indeed have a role in fever regulation,...different tissues throughout the body. Endothelial nitric oxide synthase is found in the endothelial cells of the blood vessels where it plays a big role in b...Research breakthrough identifies 291 genes associated with asthma
... as growth factors, connective tissue proteins and nitric oxide. In particular, the arginine transporter (the protein that carries it across the cell membrane) and the enzymes that act on it, arginase I and arginase II, were found to play an important role. The researchers found that the breakdown of arg...Newly mapped enzyme could yield new treatments for female sexual dysfunction
... fostering sexual arousal. "Ever since the enzyme nitric oxide synthase was identified in the female genita...hip ritual. At one critical step in that pathway, nitric oxide synthase converts arginine, one of the 20 natural amino acids, into citrulline and nitric oxid...