Leader in cancer treatment and prevention research honored
...ded, "We are just beginning mechanistic studies of novel agents which hit and disable specific molecular ta...of early precancerous lesions in the breast, using novel nipple lavage capabilities." Dr. Alberts will give an award lecture, entitled "Cruising Down the Che...UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...duals to develop new biotechnology and establish a novel training program for scientist-physicians. "Everyone has a friend or family member who has the metabolic syndrome, so it's a common problem. The Dallas Heart Study gives us a real snapshot of what the exact prevalence is in Dallas," Dr. Malloy said. ...Chemical derived from vitamin-E shows early promise as cancer drug
... at Austin have gained preliminary evidence that a novel compound that resembles vitamin E halves the size ...f genetically identical mice, which were given the novel vitamin E compound either orally or by aerosol. Based on earlier, similar findings by Kline and ...Researchers find color sensitive atomic switch in bacteria
...functions," Spudich said. In the longer term, the novel protein found in Anabaena has the potential to be used in nano-machinery as a color-sensor; however the authors point out that this practical application is years in the future. First author of the paper is Lutz Vogeley, a graduate student in the UC...Pack-MULEs are toting a new look at plant evolution
... University, Zhirong Bao and Sean Eddy, to adopt a novel genomewide approach, using computers to examine the whole genome sequence of rice. "This shows the power of collaboration," Jiang said. They've found that indeed the Pack-MULEs are numerous. They appear to copy themselves prolifically some 3,000 ti...Alzheimer's disease is not accelerated aging
...e, or they may experience difficulties in complex, novel situations. Buckner says the data suggest that changes in executive function are due to age-associated influences on frontal-striatal circuits of the brain, including an area called the corpus callosum a tract of white matter that connects the ...Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...reclinical development programs are focused on two novel cancer antigens, according to a recent company press release. Cerus is collaborating with Johns Hopkins University to develop a listeria-based vaccine targeting pancreatic and ovarian cancers that express the Mesothelin antigen, and has partnered wit...Award winning researchers reveal potential new role for Glivec
...atory agencies to develop strategies for approving novel agents that displayed significant activity in rare diseases. "Possible approaches include registries," he said, "but ultimately, international cooperation in trials such as ours (the Imatinib Target Exploration Study Team ImTEST) will provide the be...Gene clusters predict atherosclerosis severity, susceptibility
...ed in the development atherosclerosis, we took the novel approach of trying identify clusters of genes that may help us better understand the progression of the disease," said Duke cardiologist David Seo, M.D. The results of the Duke research are scheduled to appear in the October 2004 issue of the journal...UCSF scientist Joe Derisi named MaCarthur Fellow
...to provide the confirming evidence that SARS was a novel form of a coronavirus. At the time, the head of the Centers for Disease Control and Prevention, Julie Gerberding, called his tool the "absolute state-of-the-art probe for viral genes." But the self-described "viral hunter" is also a...DNA barcode finds four new bird species
...arge numbers of organisms and highlight those with novel barcodes that are likely to be new species." Identifying Species by DNA Taxonomists traditionally have classified organisms on the basis of their physical characteristics. They use DNA too, but current techniques are labor intensive a...Researchers create nanotubes that change colors, form 'nanocarpet' and kill bacteria
...d we will be continuing our investigations of this novel material in collaboration with our colleagues here at the University of Pittsburgh and the U.S. Army Research Office," added Dr. Russell....Keep genome data freely accessible
...l could use data from these repositories to create novel pathogens that could be used as weapons.' 'The current system also offers tremendous benefits. The panel, which was commissioned by US health and security officials, pointed to the recent experience with severe acute respiratory syndrome (SARS) as an...Certain genes boost fish oils' protection against breast cancer
...gapore. "Through this study, we have identified a novel gene-environmental interaction between certain genotypes and omega-3 fatty acids on breast cancer development," says Mimi C. Yu, Ph.D., professor of preventive medicine at the Keck School and principal investigator of the Singapore Chinese Health Stu...Scientists explore genome of methane-breathing microbe
...the genome analysis found that M. capsulatus has a novel strategy for scavenging copper, an essential element for regulating methane oxidation. "We found that M. capsulatus is a good model for studying how microbes adapt to varying copper concentrations," he says, noting that M. capsulatus uses two separat...Yale digital diagnostic technology is basis of new company, HistoRx Inc.
...n. -- HistoRx, Inc., a bioscience company offering novel digital technologies for in situ diagnostics devel...gy Ventures, said HistoRx's technology is not only novel and state-of-the-art, but it has the potential to significantly reduce the risk of clinical trial fa...Targeted therapy knocks out pediatric brain cancer in mice
... the absence of adequate model systems for testing novel therapies." Dr. Curran and colleagues used a mouse model of medulloblastoma that they had developed to examine whether selective inhibition of the Sonic Hedgehog (Shh) signaling pathway could interfere with the development and progression of the dise...Chemical genetics identifies SARS inhibitors
... that 900 human lives. Lack of knowledge about the novel virus and the absence of therapeutics were the pri...entry into cells. The successful identification of novel small-molecule anti-viral inhibitors validates chemical genetics as a rapid and effective approach w...22nd amino acid synthesized and added to genetic code of e. coli bacteria
... can be genetically programmed in cells to produce novel proteins for biotechnology," explained Joe Krzycki, a professor of microbiology. "Now it looks like nature has been doing the same kinds of experiments all along and has produced a never-before-seen translator protein for pyrrolysine." Following thei...US investment firm gives away Rhode Island-sized lands in Chile
...d to WCS by the Goldman Sachs Charitable Fund in a novel and powerful alliance that will ensure conservation in the region in perpetuity. The announcement was made last Friday in Chile. "This announcement underscores the important role the private sector can, and must, play in the efforts to save wildli...