JCI Table of Contents, November 3, 2003
... 5 x 10-5 per genome per day far exceeded that of nuclear DNA. In an accompanying commentary in the same is...nstitute reveal that the aryl hydrocarbon receptor nuclear translocator (ARNT) affects the structure of ceramides in the skin and disrupts the function of the ...Fruits offer powerful protection from skin cancer
...n levels; and protein levels of proliferating cell nuclear antigen (PCNA), all of which are established markers of tumor promotion. Resveratrol also further stimulated a UVB-mediated increase in p53 protein levels and was found to inhibit UVB exposure-mediated increases in cell cycle promoting signals inclu...Intraepithelial neoplasia may be a leading risk factor for prostate and ovarian cancers
...t in the development of prostate cancer, including nuclear and glandular features of prostate tissue, cell pr...chine vision, researchers identified more than 100 nuclear and glandular features, including nuclear size, roundness, optical density, number of gaps and mean ...UCSD, VA and Cal-(IT) wireless technology to enhance mass casualty treatment in disasters
...itor the location of toxic plumes from chemical or nuclear attacks, via a component of the PDA which displays a map of the immediate region, so that providers can avoid entering a "hot zone" while caring for patients. This technology is based on use of sensors monitoring local weather conditions and advance...Purdue team solves structure of West Nile virus
...ation of cryoelectron microscopy, crystallography, nuclear magnetic resonance, biochemistry and molecular biology to elucidate the processes of viral entry, replication and pathogenesis. Approximately 100 research scientists, including 50 graduate students, comprise the Markey Center....Illinois professor wins Nobel Prize
...." Lauterbur was among the first scientists to use nuclear magnetic resonance in the studies of molecules, solutions and solids. He was the first researcher to produce an image with NMR and apply the technology to medicine. This led to the development of the magnetic resonance imaging scanner, which has had ...McMaster University researchers race to SARS vaccine development
...Mahony who cloned the gene that marks an important nuclear protein of the SARS virus. A research team at McMaster then inserted the nuclear protein gene into an engineered common cold virus, or adenovirus vector, and will shortly test this ...Aggregation of cloned mouse embryos improves survival rate
...rovides a new insight into reprogramming following nuclear transfer," said Davor Solter, a developmental biologist at the Max-Planck Institute of Immunobiology who was not involved in this work. "It confirms indirectly that every cloned embryo is actually different and that reprogramming is random. It seem...UCSD researchers discover gene able to suppress retrovirus insertion mutations
...ified a novel change in mice in a gene called mRNA nuclear export factor 1 (Nxf1). This gene normally acts a...Mvb1, and to determine that it is part of the mRNA nuclear export factor Nxfl. The team further showed that the variation in Nxf1 that allows it to suppress r...Long-term natural gas supplies should meet growing demand in coming decades, study finds
...e consumption. Technological advancements in coal, nuclear and other energy sectors could reduce demand for natural gas, the authors wrote. However, the report found that renewable technologies, such as wind and solar power, will have a relatively minor impact on natural gas markets in the next 20 years but ...National lab trains U. S. customs agents against WMD
...ing program has led to several seizures of special nuclear materials and dual-use commodities overseas. Since its creation in 1997, RADACAD has trained more than 300 border agents from nearly 20 foreign countries. "The combination of the U.S. and international training programs means there are two lines of...Lasker Award honors Rockefeller University biochemist for pioneering studies of gene activation
...raction between it and specific activators such as nuclear hormone receptors, proteins involved in development and homeostasis, and p53, a protein implicated in at least 60 percent of human cancers. The researchers previously revealed that thyroid hormone receptor and p53, which both are known to activate se...Francis Collins and Ari Patrinos receive Energy Secretary's Gold Award for Human Genome Project
...g the Genomes to Life program, structural biology, nuclear medicine and health effects, global environmental change and basic research underpinning DOE's environmental restoration effort. He is a member of the American Society of Mechanical Engineers, the American Geophysical Union, the American Meteorologi...54th Annual Arctic Science Conference highlights extreme events
...uakes and eruptions, to oil spills, fires, floods, nuclear events and rapid changes associated with global warming. Crises will also be considered from an anthropological perspective, and science education outreach will be discussed. A concluding technical session will discuss how science and public policy w...Study at TSRI links dozens of proteins to several rare muscle and nerve degeneration diseases
...roteomics to identify 62 new proteins in the inner nuclear membrane of the human cell. The team demonstrated ...devastating diseases have been linked to the inner nuclear membrane, which lines the nuclear envelope compartmentalizing the cell's genetic material or DNA. On...Grant renews funding of research toward cloning primates
...l Science. Despite using four common techniques of nuclear transfer in more than 700 eggs from rhesus macaques and 33 transfers of early embryos into surrogates, no pregnancies were established, Dr. Schatten and his colleagues reported. Among the key structures involved in cell division is the mitotic spindl...UT Southwestern gets new cryo-electron microscope
...ficult to be analyzed by X-ray crystallography and nuclear magnetic resonance spectroscopy," Dr. Kikkawa said. "The new cryo-EM will fill the gap between such atomic-level understanding of these molecules and cellular-level activities." Similar to a patient having a magnetic resonance imaging (MRI) or comput...Pinpointing viruses in body scans
...tected through magnetic resonance imaging (MRI) or nuclear magnetic resonance (NMR) scans. "The antibodies recognise specific proteins on the surface of the virus, and it makes the nanoparticles clump with the virus," explains Perez. But the scanners do not detect the nanoparticles directly. First, the part...New study rebuts claims about Icelandic genetic heterogeneity
...e new study, says: "A consideration of 83 unlinked nuclear SNPs, 14 serogenetic loci, Y-chromosome haplotypes constructed from five microsatellites and mtDNA HVS1 and HVS2 control region sequences, provides a clear and consistent picture of Icelanders being amongst the more genetically homogeneous population......eved to be mediated by their interactions with the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma). As PPAR-gamma is expressed primarily in fat cells, with lower levels in skeletal muscle, it has remained debatable whether the effect of TZDs on muscle is direct or indirect. Usi...