Systems tool new resource to aid groundwater cleanup
RICHLAND, Wash. -- After almost 50 years of nuclear materials production at the 586-square-mile Hanford Site in southeastern Washington, there are more than 700 waste sites with the potential to release contaminants to the soil and groundwater. These sites vary significantly in their inventories of ra...UW-Madison scientists return to rat as biomedical research tool
...ice. Moreover, no rat has even been produced using nuclear transfer or cloning techniques, another method by which researchers can selectively modify an animal's genome. The development of the world's first knockout rats by Gould's lab was accomplished using techniques well know to biologists, but that had n...Diabetes in the elderly linked to fewer cellular 'power plants'
...nsulin resistance. The researchers next turned to nuclear magnetic resonance spectroscopy (NMR), to zero in on muscle cells to determine whether they were accumulating fat. In NMR spectroscopy, harmless magnetic fields and radio frequency pulses are used to detect and quantify signals characteristic of spec......reliable techniques that amplify mitochondrial and nuclear DNA from an animal's dung. Their new protocols ha...by PCR (Polymerase Chain Reaction) for a number of nuclear loci multiple times. A minor level of error was seen in the DNA extractions between the blood and d...Study of nature's machinery takes center stage at UH
...feet tall and 6 feet in diameter, an 800 megahertz nuclear magnetic resonance (NMR) spectrometer was delivered to UH in January. On May 16 and 17, top experts in the field of biomolecular NMR will gather at UH to dedicate the machine and participate in a special symposium devoted to protein science. "This NM...JGI and Diversa Corp. announce large-scale microbial sequencing collaboration
...sea thermal vents, insect endosymbionts, soil from nuclear weapons manufacturing sites, and water collected by rainforest epiphytes such as bromeliads that grow on giant trees. Diversa pioneered proprietary, genomics-based methods for discovering unexplored microbial diversity and recently received a patent...March of Dimes awards $250,000 prize to pioneers in genetic research
...ology, CNRS/INSERM, Strasbourg, France, discovered nuclear hormone receptors, revealed their structure and fu...ns and Prof. Chambon have illuminated the roles of nuclear hormone receptors in human health and disease," Dr. Howse says. "Their discoveries opened up produc...Argonne research offers clues to Alzheimer's plaques
... fibrils at the University of Chicago, solid-state nuclear magnetic resonance (NMR) studies were performed at Botto's lab at Argonne. The researchers replaced specific amino acids in the truncated peptide, one at a time, with those containing carbon-13 isotope, enabling them to measure the distances between ...One fig, one wasp? Not always!
...cies pollinates each fig species. Molbo developed nuclear microsatellite markers to test the sex ratio theor...cies of pollinator wasp. Molbos analysis based on nuclear microsatellites matched perfectly with groupings based on mitochondrial genes sequenced by Carlos Ma...The mechanics of anti-tumor activity outlined
... 2ME2 depolymerizes microtubules and blocks HIF-1a nuclear accumulation and HIF-transcriptional activity, or the transfer of genetic code information from one kind of nucleic acid to another. "This research is important because we see for the first time a mechanistic link between targeting of the microtubu...Heinz Maier-Leibnitz Awards 2003
...the 15th May. Named after former DFG President and nuclear physicist Heinz Maier-Leibnitz, the award is funded by the BMBF in recognition of the excellent research achievements of young scientists under the age of 33. The award winners were selected in a multistage selection process out of a total of 74 prop...Researchers identify gene for premature aging disorder
...the cells from the progeria patients had misshapen nuclear membranes, compared with less than 1 percent of th...controls. "We suspect that this instability of the nuclear membrane may pose major problems for tissues subjected to intense physical stress tissues such as t...Discovery of proteins necessary for HIV release suggests possible new therapeutic targets
...f key components in HIV assembly. By incorporating nuclear magnetic resonance imaging, cryogenic electron microscopy, genetic analysis, and other technologies into his lab, he has produced compelling findings that have made him a leader in the field of HIV research and structural biology. Perhaps more signif...Carnegie Mellon University research story ideas on DNA
...ts, including elegant integrated computational and nuclear magnetic resonance research that quickly generates structural "sketches" of unknown proteins and amazingly arrives at an unknown protein's structure without any reference to its amino acid sequence. This approach should accelerate the characterizatio...Difficulties with primate cloning: A religious comment
...will not in fact lie along the lines of cloning or nuclear transfer but through other approaches that may be technically challenging but less problematic morally. Its time to remove the cloning monster from the debate so that medical research using embryonic stem cells can move forward with strong support. ...Failures in primate cloning may signal impossibility of human reproductive cloning
...lopment despite using four different techniques of nuclear transfer, according to Gerald P. Schatten, Ph.D., ... Schatten and his colleagues used known methods of nuclear transfer on 724 eggs retrieved from female rhesus macaques. Although 33 embryos were transferred int...Amorous worms reveal effects of Chernobyl
...S contaminated by radioactivity from the Chernobyl nuclear accident have started having sex with each other instead of on their own. According to Ukrainian scientists, they may have changed their sexual behaviour to increase their chances of survival. It's one of the first pieces of direct evidence on how wi...The structure behind the switch
...ting-and-splicing mechanism that occurs within the nuclear DNA of B cells, which are key components of the im...antibody belongs. It, too, is created via a B-cell nuclear cut-and-paste job, but the mechanics here are much more complicated-and until now, much less well un...Project BioShield: Consistent financing, markets, indemnity for biodefense vaccine developers needed
...cal weapons threat is of similar importance to the nuclear threat in many respects. The Strategic Defense Initiative, which celebrated its 20th anniversary last month, launched a missile defense program whose funding has not dropped below $3 billion dollars annually over two decades. That kind of long-rang...Tracking every egg? AAAS report lists practical options for regulating human cloning
...oductive cloning? Both involve a technique called nuclear transplantation--replacing the nucleus of a donor's egg with the DNA from an adult cell. Under certain conditions, the resulting entity will begin developing like a fertilized egg. In reproductive cloning, the entity is implanted into a uterus, where...