RNA editing process plays essential role in embryo development
...protein was fairly straightforward: DNA in a cells nucleus is transcribed to RNA, and then sometimes shortened to splice out noncoding sections to form mature messenger RNA. The mature messenger RNA is transported to the cells cytoplasm, where translation to protein occurs. But researchers learned that ma......Furthermore, they found that NAC1 functions in the nucleus by binding to DNA. Using these insights, the team was able to identify NAC1 as a classical gene regulator. Dr. Chua and colleagues then went on to discover two targets of NAC1, both of which had already been shown to be responsive to auxin signaling....Cytoplasmic FRAP must enter and exit nucleus to perform
...smic world between a mammalian cell's membrane and nucleus undergoes a "nuclear experience" that is necessary...ents. If FRAP fails to briefly enter and exit the nucleus then some crucial proteins fail to synthesize, thereby preventing cell growth and proliferation. "T...Human reproductive success tied to mitochondrial organization in eggs
...y DNA structures in the eggs fluid surrounding its nucleus prior to the first cell division, according to a new Colorado study. University of Colorado at Boulder biology Professor Jonathan Van Blerkom said the study showed the roughly 140,000 tiny DNA structures, or mitochondria, in each egg are controlled b...Blood test for diagnosing schizophrenia
...needed for making dopamine receptors from the cell nucleus to the ribosome, the small cellular "factory" where the receptors are manufactured. A statistical analysis showed that the blood of patients with schizophrenia contains, on average, 3.6 times more messenger RNA molecules of dopamine receptors of a p...Epstein-Barr virus linked to invasive breast cancer and lymphoma
...t to its latent phase -- where it hides inside the nucleus of immune cells called lymphocytes without producing any symptoms. Even though the virus is endemic in humans, Robertson emphasizes that most cells infected by the virus may never become malignant. Additional genetic factors are required to trigge...Researchers light the path of brain's feeding circuit in mice
...s first spread throughout the cells of the arcuate nucleus itself, causing the neurons containing the Cre recombinase gene to glow green (from the GFP). The virus then spread from these cells to other cells that were in contact with it, and so on. As the virus infects each neuron, it amplifies itself, allowi...Researchers link failed cell division, Alzheimer's disease
...se it's stopped there and not able to proceed, its nucleus is basically out of balance with its surrounding cell structures. Normally, the cell machinery expects two copies of a given gene, but in Alzheimer's disease there are four because the DNA is replicated. Since the cell hasn't divided it is sitting wi...Keeping a tight rein on cell division
...e ERKs further modified so that they can enter the nucleus and prompt the cell to multiply. Many cancer cells can grow without contacting anything, or when they are contacting an unusual surface in a different part of the body that they do not usually encounter. The cancer cells may gain this ability by modi...Yeast cells place their nucleus in the center of the cell, where the nucleus helps define where the cell will later divide in half. Researchers now report evidence supporting a ...Scientists track down the root of cloning problems
...ommand center, of an egg and replacing it with the nucleus of an adult cell. The egg resets the development...b found that the genetic background of the donated nucleus influences clone survival, independent of the cloning procedure. When the researchers studied clones...Dartmouth researcher goes to Cape Cod to study cell division
...division, and his lab also discovered that a cells nucleus appears to store p62 for use during this process. ...l focus on two questions: is p62s residence in the nucleus required for healthy cell division, and what other proteins interact with p62 during cell division. ...Krauss book explores universe from oxygen atom's perspective
...f which have had their own adventures, to form the nucleus of an oxygen atom. After this star also explodes in a supernova, this atom ultimately makes its way to earth. "One of the most poetic things that I know about the universe is that every atom in our body may have once been deep inside an exploding st...'Silent' DNA speaks up for the first time
...s a copy of the genes DNA that departs from a cell nucleus to transport genetic information. The researchers discovered that the enzyme responsible for producing mRNA is present even on the silent genes. The process that makes some genes silent could itself help scientists understand aging. Yeast cells...Scientists find that heart muscle cells regenerate after a heart attack
...ure the expression of Ki67, a protein found in the nucleus of dividing heart muscle cells. Ki67 is expressed during all phases of a cells life cycle and is a strong indicator of cell division. The scientists also obtained images of mitotic division and found other evidence of myoctye replication, includi...Study reveals molecular key to tumor suppressor activity
...als occur, the p53 protein accumulates in the cell nucleus where it can either program the cell to self-destr...onsible for transporting the protein from the cell nucleus to the cytoplasm, where it would get degraded, broken down. Moreover, they discovered how this trans...Biologists: Cell nucleus surface more complicated than expected
...ts are taught that each plant or animal cell has a nucleus a simple, round sphere containing the organism's ...ion of chemical messages and molecules between the nucleus and cell parts contained in the cytoplasm, because greater surface area may allow more molecules and...Gene therapy restores feeding behavior to starving mice
...d into two segments -- the caudate putamen and the nucleus accumbens. Mark S. Szczypka, a postdoctoral ...ore dopamine production in the caudate putamen and nucleus accumbens, by injecting harmless adeno-associated viruses carrying the genes for tyrosine hydroxylas...Scientists decipher "fail-safe" system that limits gene copying in cells
...n human cells, DNA replication is triggered in the nucleus when proteins known as replication factors position themselves at hundreds to thousands of pre-determined sites along the DNA molecule. Li's UCSF team knew that a specific set of proteins called kinases played a central role in preventing this critic......r own research using nuclear genes (genes from the nucleus or core of cells) has shown a nearly 100 percent statistical likelihood that the Duke results are correct. Mitochondria are the cell's power plants and possess their own genes that are inherited through the maternal line. Scientists use this met...