COX-2 inhibitors and renal damage in obesity-related Type II diabetes
...ncontrolled appetite and, consequently, results in obesity and its associated characteristics (insulin resistance, hypertension, etc.), although the mechanisms responsible for renal damage in the Obese Zucker rat remain unknown. Methodology Obese Zucker rats at 10-12 weeks or 20-21 weeks of age were studi......erweight Americans has reached record levels, and obesity now affects almost one in three citizens. Publishe... (28 percent). While there is little difference in obesity rates among men across racial/ethic lines, obesity rates for African-American, Mexican-American and ...Obesity, kidney genetics, erectile dysfunction among highlighted research at APS Meeting
...and a High-Fat Diet The exact mechanisms by which obesity causes hypertension are not fully understood, but has been linked to the kidneys. That's because the kidneys play a key role in regulating blood pressure, and substances, which affect renal salt and water excretion, are important modulators of hypert...Researchers involved in renal and cardiovascular function gather for fall conference
...and a High-Fat Diet: The exact mechanisms by which obesity causes hypertension are not fully understood, but has been linked to the kidneys. That's because the kidneys play a key role in regulating blood pressure, and substances, which affect renal salt and water excretion, are important modulators of hypert...Cellular problem discovered behind syndrome of obesity, learning disabilities
...on't know yet how the ciliary defect might lead to obesity or learning disabilities, but the finding provides a new avenue to studying these genetically murky traits. "It is very difficult to translate genetic understanding into a cellular mechanism that explains what is seen in a disease. But such efforts a...Natural fat compound may be basis for new class of drugs targeting obesity
...ay be the basis for a new class of drugs targeting obesity and other eating disorders. Daniele Piomelli, pro...or obesity. "There are many drugs being tested for obesity in current clinical trials, but most don't succeed because they are not well tolerated by patients,"...Mouse, stripped of a key gene, resists diabetes
...es critical genetic and biochemical clues to diet, obesity and the onset of a disease that affects as much as...he sugar's energy is expended. In many instances, obesity and diabetes go hand in hand. Between 75 and 80 percent of people with type II diabetes are obese, a...Study seeks genetic keys to exercise success
...es in body mass and composition, fat distribution, obesity status, blood chemistry, blood pressure and heart rate of volunteers after 30 weeks of exercise. UH students who volunteer for the study will enroll in special sections of Exercise for Health and Fitness, a three-day-a-week class that involves 30 m...UT Southwestern gets new cryo-electron microscope
...s disease, spinal-cord injuries, cancer, diabetes, obesity and cholesterol metabolism. Specifically, scientists can learn how viruses like herpes simplex virus type I (which causes cold sores) infect cells, as well as continue their detailed study of the human genome. "This is a state-of-the-art instrument t...Couch potatoes may be created in the womb, not at the dinner table
...ieties such as the United States, the incidence of obesity is approximately 32 percent of the adult populatio... and lifestyle are adopted. Although the causes of obesity are multifactorial, these recent increases have been too sudden to be explained by genetic factors. ...Smaller food portions may explain the 'French paradox' of rich foods and a svelte population
...one assumes that dietary fat is the major cause of obesity and cardiovascular disease," said Paul Rozin, professor of psychology at Penn and lead author of a paper in the September issue of the journal Psychological Science. "However, recent studies suggest that the importance of fat intake as a risk factor...Estrogen found as link between obesity and breast cancer in postmenopausal women
...HIA (August 13, 2003) Researchers have known that obesity is associated with an increased risk of breast can...ue of the Journal of the National Cancer Institute obesity increases the risk of breast cancer in postmenopausal women by increasing the amount of estrogens in...Natural hormone could reverse heart damage
...chers studied leptin's effects in a mouse model of obesity that also develops left ventricular hypertrophy (L...for leptin, and the third was normal. Progressive obesity developed in the mice lacking leptin or its receptor, and by 6 months of age, researchers observed L...Home visits from community health workers spur blood pressure reduction
...tarted health programs to address substance abuse, obesity and arthritis. The team also worked closely with a free health clinic for residents that had been established....New protein may play a role in obesity
...s that will block C5L2 activity." In North America obesity is at epidemic levels in all age groups. A large p...tion, Metabolism and Diabetes which has identified obesity research as its strategic funding priority. "We need to know much more about human biology, as well ...Diadexus receives FDA marketing clearance for PLAC (TM) test
..." cholesterol), smoking, diabetes mellitus, marked obesity or physical inactivity. "The PLAC test is an important new tool which physicians may use to more accurately predict who is at risk for heart disease," said Christie Ballantyne, MD, director of the Center for Cardiovascular Disease Prevention at Bayl...Inflammation blocks impact of heart healthy diets for some
...een identified -- along with cigarette smoking and obesity -- as a risk factor for cardiovascular disease. The 100 healthy adults in the study had an average age of 52 and already were participating in the national Dietary Approaches to Stop Hypertension-Sodium (DASH-Sodium) trial. The Hopkins team took...JCI table of contents, July 15, 2003
...ps://www.the-jci.org/press/18106.pdf OutFOXing obesity Obesity results from a massive expansion of fat c...t cells. Furthermore, in multiple rodent models of obesity they observed that Foxa-2 production is increased, in what may be an important counterregulatory mec...Obese mice provide clues to a natural system that puts brakes on obesity
...fat cells of obese mice may be a key to preventing obesity in humans, according to new research at The Rockef... mature adipocyte, Foxa-2 seems to counterregulate obesity by increasing these enzymes in the adipocyte or at least working against further decreases." The res......dementia and AD. It has been hard to determine how obesity and overweight affect risk in AD because weight lo...University in Gothenburg, Sweden. "Overweight and obesity are very closely associated with vascular diseases, such as diabetes, coronary heart disease and hyp...