Benefits of lung surgery reported for emphysema patients
... said Steven Piantadosi, M.D., Ph.D., professor of oncology at Johns Hopkins and a lead investigator in the study. Added Robert Wise, M.D., professor of medicine at Johns Hopkins and an author of the report, "They also tell us which patients will respond well to surgery and which ones are at risk of complicat...ESMO Summer Educational Conference, ESEC
...nal experience' will focus on conventional medical oncology such as gynecological and colorectal tumors, as well as emerging fields like psycho-oncology and quality-of-life. ESEC will confront difficult situations and areas of treatment that require special attention. It will address the question of what pati...UW-Madison scientists return to rat as biomedical research tool
...ockout rat," says Michael N. Gould, a professor of oncology at UW-Madison's McArdle Laboratory for Cancer Research and in whose laboratory the work was conducted. For 100 years, he explains, the rat was the model of choice for many biomedical scientists. But a decade ago, when knockout technology was first wi...Hopkins scientists uncover role of Fanconi's Anemia genes in pancreatic cancer
...ncer," according to Scott Kern, M.D., professor of oncology and pathology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and director of the study. The good news is that these genes offer new targets for improved treatment, he says. The genes have all been associated with Fanconi's Anem...Systematic analysis of gene family uncovers new therapeutic targets for colon cancer
...E. Velculescu, M.D., Ph.D., assistant professor of oncology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, who led the research effort. "Our findings open the door to individualized analysis and treatment of colorectal cancer," says Velculescu. TKs are so-called activating prot...Researchers discover effective method for killing prostate cancer cells
... Marja Nevalainen, MD, PhD, assistant professor of oncology at Georgetown University Medical Center. "It's similar to using a weed killer -- poison ivy cannot take over the backyard if we don't allow the leaves to breathe. If we stop this protein, which in turn stops the growth of prostate cancer cells, we ...Scientists report discovery of cancer-causing gene in childhood kidney tumor
...-Farber and Children's, an instructor in pediatric oncology working in Fisher's lab, performed molecular tests on the tumor cells and found the TFEB gene was indeed split apart, with the main region being fused to the "gearbox" the on-and-off switch of a gene on a completely different chromosome. The error ...Common thyroid cancer gene mutation found
...d Sidransky, M.D., professor of otolaryngology and oncology at Johns Hopkins. "Our goal is to find better diagnostics and drug therapies designed to target the effects of this mutation." The mistake involves a subtle change in the chemical bases (adenine, thymine, cytosine, and guanine) that make up DNA. Th...Scientists find new way to grow human embryonic stem cells
... says Linzhao Cheng, Ph.D., assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "Marrow stromal cells co-exist with blood-forming stem cells in bone marrow and support their growth in the lab, but we were surprised they could fully replace mouse cells in supporting more primitive ES cel...... Ireland Cancer Center, and professor of radiation oncology at CWRU, the research team spent nearly a decade d...D., a member of the team and director of radiation oncology at the Ireland Cancer Center and chairman of the department of radiation oncology at UHC and CWRU. ...Presence of certain tumor markers for melanoma could signal best results for vaccine
...," said Dr. Dave S. B. Hoon, director of molecular oncology at the JWCI and the study's principal investigator...a is a major focus of our studies in the molecular oncology department at JWCI," added Dr. Hoon....Firefly molecule could quickly shed light on how well new drugs work
...ehemtulla, Ph.D., associate professor of radiation oncology at the U-M Medical School and co-director of the U-M Center for Molecular Imaging. "This proves that we can see what's going on at the molecular level while the drugs are working, giving results in days or weeks instead of months or years.' The proce...Common cancer gene controls blood vessel growth
...," says Roberto Pili, M.D., assistant professor of oncology in the Kimmel Cancer Center and co-author of the study. "But it could potentially be paired with another molecule and programmed to be released only in tumors." In addition to TSP-1, Alani and colleagues are studying Id1 targets important in other ...Hopkins study finds combined PET-CT better at detecting ovarian cancer
...lliot K. Fishman, M.D., professor of radiology and oncology and director of diagnostic imaging and body CT for the Kimmel Cancer Center at Johns Hopkins. The researchers caution that this study is in a limited number of patients and additional research is necessary to determine the value of combined PET/CT ov...Aspirin inhibits ovarian cancer growth, lab study finds
... co-author Janet Drake, MD, formerly a gynecologic oncology fellow at USF. Last year, Dr. Becker's laboratory demonstrated that aspirin inhibits the growth of endometrial cancer by promoting programmed cell death, or apoptosis. USF continues its preclinical studies to determine how aspirin inhibits tumor cell......some of the 2,000 European and American experts in oncology gathered in Frankfurt to share findings and discuss the latest research on new molecular targets, designer diagnostics and prognostics, smart drugs and other novel approaches to tackling cancer. NB: the official language of the symposium is English. ...Maternal alcohol use during pregnancy may increase offsprings breast cancer risk
...cer," says Dr. Leena Hilakivi-Clarke, professor of oncology and director of tumor biology, Georgetown University, Washington, DC, and senior investigator of the study. Diet can increase circulating estrogen levels; high in utero estrogen levels increase breast cancer risk by making the developing breast cell...The role of obesity and calories in cancer prevention
...cording to Dr. Leena Hilakivi-Clarke, professor of oncology and director of tumor biology, and lead investigator of the study. "Exposure to estrogen around puberty has been demonstrated to decrease the risk of developing breast cancer later in life; however, this is not an optimal chemoprevention method." Th...First-ever cancer prevention research meeting
... still much to be learned." Some 1,000 scientists, oncology experts and others interested in cancer prevention are attending Frontiers in Cancer Prevention Research....Big-bottomed sheep have a rare genetic mutation that builds muscle, not fat
..., said Randy Jirtle, Ph.D., professor of radiation oncology at Duke and co-author of the study. "These sheep are, in effect, pumping iron without lifting weights," explained Jirtle. "They are converting food into muscle in their hind regions, instead of converting food into fat." Results of the study, funded...