Engineered virus provides impetus in search for HIV vaccine
...a multi-institutional research report that appears online today in the Proceedings of the National Academy of Sciences. In this work, a vaccine vector has been engineered that uses potent features of adenovirus that normally infects respiratory tissues and of reovirus that infects the mucosal membranes of ...Surprises found in gene variation associated with schizophrenia
...2pb. The study results appeared in the February 11 online issue of the American Journal of Medical Genetics. "While this polymorphism makes us more vulnerable to a certain illness, in this case schizophrenia, overall it is evolutionarily beneficial," said Robert Philibert, M.D., Ph.D., UI assoc...U of T researchers isolate gene for Crohn's disease
... and then identify the gene. Their findings appear online April 11 in Nature Genetics ( www.nature.com/ng/ ). The gene isolated by the researchers produces a protein that sits on the cell surface and regulates how substances enter and exit the cell. In a majority of Crohn's disease patients, this protein fu...Scientists 'beef up' plant-dwelling bacteria to boost phytoremediation
...ay 2004 issue of Nature Biotechnology , available online April 11 ( http://www.nature.com/biotech/ ). "By introducing genes for the appropriate degradation pathways into natural plant-dwelling bacteria, known as endophytes, we should be able to tailor-make plants capable of cleaning up a variety of organic...DNA research highlights prostate cancer mechanisms
...r, but the new research, described in the March 25 online edition of Carcinogenesis, provides the first solid evidence that the normal repair process is altered in prostate cancer cells, possibly leading to a cascade of events that culminate in further DNA damage and cellular dysfunction. Free radicals---h...Study suggests insect-derived antimicrobial peptides could be used as drug-delivery vehicles
...l membranes and tissues. In their study, published online today in Molecular Pharmaceutics, the researchers showed that native pyrrhocoricin can penetrate human dendritic cells, an important type of immune cell, and that the designer pyrrhocoricin analog can penetrate both dendritic cells and fibroblasts, a...UF study: Barren Siberia, of all places, may be original home to animal life
...ansas that is scheduled to appear next week in the online edition of the London Journal of the Geological Society. By comparing separate, seemingly unrelated findings on trilobite evolution and geological history, UF's Joe Meert and KU's Bruce Lieberman concluded that precursors to modern continents began ...Introduction of the 'Rett protein' in post-mitotic neurons rescues Rett Syndrome in mice
...arch in Cambridge, MA reports in the April 6, 2004 online issue of the Proceedings of the National Academy of Sciences that introduction of the MeCP2 protein into post-mitotic nerve cells of MeCP2 mutant mice rescues the symptoms of Rett Syndrome. This raises the possibility that neurons are functionally no...Annual bioethics forum to explore genetic testing
...formation, including links to a forum brochure and online registration, visit http://www.btci.org or call 608-273-9737....UT Southwestern researchers reveal mechanisms of smooth-muscle contraction
... National Academy of Sciences and was to be posted online this week. Dr. Stull and his colleagues discovered that when one of the chemicals in the primary contraction mechanism a protein called calmodulin is in short supply, a second series of chemical reactions kicks in to take up the slack. The re...Last call for nominations for 2004 National Academies Communication Awards
... categories: -Book author -Newspaper, magazine, or online journalist -TV/radio producer or reporter Nominations must be postmarked no later than April 15, 2004. The winners will be honored at the National Academies' Beckman Center in Irvine, Calif., during the Keck FUTURES Conference to be held Nov. 19-21,...American Society for Microbiology 104th general meeting
...ned by calling the ASM Office of Communications or online at http://www.asm.org/Media/index.asp?bid=2673 . Additional press materials can be found at this site as they become available. PLEASE NOTE: The housing deadline is April 16, 2004. While media will be allowed to register for the meeting after th...Missing gene a potential risk factor for birth defects
... such as ionizing radiation. In a study published online by the FASEB Journal in March, researchers at U of T's Leslie Dan Faculty of Pharmacy found that mice embryos genetically engineered to lack one or both copies of the ATM gene and then exposed to ionizing radiation and a subsequent overload of reacti...Carnegie Mellon U. conducts first comprehensive proteomic analysis of developing animal
...orks and harm development. The research, reported online ( http://dev.biologists.org/content/vol131/issue3/ ) and in the February 1 issue of Development, found that specific cells set to change shape during a key growth step are actually poised for their transformation far in advance and that many types of...STN International launches Derwent World Patents Index First View
...European partner of premier science and technology online service STN International, has launched Derwent Wo...ernational can be accessed by dialling in to STN's online service using its powerful proprietary client software, STN Express with Discover! Alternatively, it...... Sciences (PNAS) and was scheduled to be published online this week. The study was supported by the National Institute of Dental and Craniofacial Research (NIDCR), which is part of the U.S. National Institutes of Health. The researchers found that T. denticola has more than twice as many genes as the spiroc...Study points to a promising new test for myelodysplasia, a blood disorder often leading to leukemia
... of the National Academy of Sciences and appearing online the week of March 29th describes a promising new test for the early diagnosis of a serious blood disorder that can lead to bone marrow failure and acute myelogenous leukemia. Myelodysplastic syndrome (MDS), diagnosed in about 15,000 to 20,000 people...NIST-led research de-mystifies origins of 'junk' DNA
... team, which reported its findings in the March 10 online edition of Molecular Biology and Evolution . The results are based on a systematic, statistically rigorous analysis of publicly available genetic data carried out with bioinformatics software developed at CARB. In humans, there is so much apparent "...Study shows benefits to newborns from federal ban on insecticides
...reviewed journal of the NIEHS. It is now available online at http://ehp.niehs.nih.gov . The study, released by the Columbia Center for Children's Environmental Health, part of the Mailman School of Public Health at Columbia University, measured the impact on fetal growth of two insecticides - chlorpy...