5AM Solutions releases Microarray Enterprise Manage(TM) Software
... data annotation, and dissemination. Web lectures, online help, and example projects represent the educational components of the software. Experimental methods and protocols can be shared, reducing the amount of data entry and enforcing consistency. MEM simplifies data standardization through a novel method...Nerve cells 'guided' to repair spinal damage: Technique
...inal cords. The technique, outlined in the July 6 online version of Biomaterials, involves imbedding a series of fibrous rods into a gel substance and then dissolving the rods, leaving a series of longitudinal channels. These channels are then injected with peptides, molecules that stimulate cell adhesion ...Prions act as stepping stones in evolution
...r of the paper, which will appear August 15 in the online edition of the journal Nature . Previously, True and Whitehead Institute Director Susan Lindquist reported that a particular yeast protein called Sup35 somehow altered the metabolic properties--or phenotype--of the cell when it "misfolded" into a ...Last of known genes identified in complex obesity syndrome
...in these families. Writing in the Aug. 15 advance online section of Nature Genetics, the international team reports that BBS3 is actually a gene formerly known as ARL6. Importantly, ARL6 is the first BBS culprit to belong to a family of genes and proteins with a known function, opening the door to figuring...Schizophrenia gene variant linked to risk traits
...ngs of the National Academy of Sciences, published online the week of August 9, 2004. Glutamate is a key neurotransmitter long thought to play a role in schizophrenia. The gene identified in this study makes the glutamate receptor (GRM3) which is responsible for regulating glutamate in synapses--spaces in b...Technology already exists to stabilize global warming
...res.) In their paper and 51 pages of supplementary online material, they identify opportunities and difficulties associated with each option and compare alternative combinations of seven "wedges." Several of the options, for example, involve capturing carbon dioxide at power plants or other locati...Gene changes linked to increased eye pressure may have implications for glaucoma therapy
...g this disease. The study currently appears in the online October issue of the Journal of Cellular Physiology . "Pressure is required in the eye to keep its shape, and this pressure is maintained in the front part of the eye by a fluid, the aqueous humor," said Dr. Teresa Borrs, the paper's senior auth...Infants sighs may 'reset' breathing regulation mechanism as well as help lungs develop
...ory and dynamics in healthy infants," is published online in the Journal of Applied Physiology, one of 14 peer-reviewed journals published by the American Physiological Society. Lead author David N. Baldwin works at the Department of Pediatric Respiratory Medicine, University Children's Hospital, B...Flame retardant levels much higher in farmed salmon
...choose their salmon carefully. The report appeared online Aug. 10 in Environmental Science & Technology , a peer-reviewed journal of the American Chemical Society, the worlds largest scientific society. Polybrominated diphenyl ethers (PBDEs), which are used widely as flame-retardant additives in electronic...Brain's reward circuitry revealed in procrastinating primates
...ngs of the National Academy of Sciences, published online the week of August 9th. Richmond's team trained monkeys to release a lever when a spot on a computer screen turned from red to green. The animals knew they had performed the task correctly when the spot turned blue. A visual cue--a gray bar on the ...Jefferson scientists find gene expression pattern may predict behavior of leukemia
... expression in development. Reporting in both the online and the August 10 print version of the Proceedings of the National Academy of Sciences, the researchers taking advantage of a microarray chip Dr. Croce and his colleagues designed that carries all the known human miRNA genes compared the expression...The telomere crisis: A crucial stage in breast cancer
...sco. Their report is now available through advance online publication of Nature Genetics. Joe Gray, directo...t, will appear in Nature Genetics and is currently online at http://www.nature.com/ng/ . Berkeley Lab is a U.S. Department of Energy national laboratory l...Scientists identify compounds that mimic calorie restriction
...eight. Their findings are published in the current online issue of the Journal of Biological Chemistry. Co-author Thomas W. Kensler, PhD, a professor of Environmental Health Sciences at the Johns Hopkins Bloomberg School of Public Health, explained that calorie restriction has intrigued scientists for deca...Promising hospital anti-infection strategy probably won't work, study shows
...f the National Academy of Sciences and will appear online the week of Aug. 9. Co-authors are Monique Lo and Marc Lipsitch of the Harvard University School of Public Health. Another implication of the work, Bergstrom said, is that cycling actually could be detrimental to patients, "so the studies need t...Genetic mutation linked to more aggressive breast cancer found more often in African-Americans
...study. This study, published August 9, 2004 in the online edition of CANCER, a peer-reviewed journal of the American Cancer Society, "represents the first reported series of increased prevalence of p53 alterations in African-American breast cancer patients," according to an accompanying editorial. Free abst...More aggressive breast cancer tumors found in African American women
...rts, Yale researchers report in the August 9, 2004 online edition of the journal Cancer. In the United States, African-American women have a lower incidence of breast cancer than white women, but they have a higher mortality rate. The disease also develops at an earlier age and is more aggressive in African......nce." Connors said the discovery, detailed in the online early edition of the Proceedings of the National Academy of Sciences for the week of August 2, could shed light on the cause of epilepsy and seizures. Scientists suspect that a Cx36 mutation causes these common neurological conditions, which occur wh...U-M scientists find common virus in human prostate tissue
...om the U-M study, published July 19 in the advance online edition of the journal Oncogene , are available at www.nature.com/onc/journal/vaop/ncurrent/ . "The development of cancer is a multi-step process," Imperiale adds. "Expression of BK viral protein may be just one step among several genetic and ...Fundamental change to Immunology 101
...hey describe their findings in the current advance online publication of Nature Immunology. Hematopoietic stem cells (HSCs) are the ultimate progenitors of all blood cell types, from platelets and red blood cells (erythrocytes) to immune cells like T cells and B cells. But T-cell development differs ...Two-month study of life in mid-Atlantic yields trove of species, new insights & questions
... media release of current expedition highlights is online at http://www.coml.org/embargo/embargo3.htm Cond... number of public and private contributors, listed online at http://www.mar-eco.no/about/sponsors...