Asian bird flu became highly pathogenic through continued circulation and gene swapping
... Vietnam and Indonesia, is published in the July 8 online edition of Nature. Reassortment is the swapping of genes when two or more viruses infect the same animal. The researchers say that their study of the genetic makeup of H5N1 subtypes collected since 1997 traces the evolution of the virus into a dan...American Chemical Society media registration
... in Philadelphia. Media can apply for credentials online at: http://www.chemistry.org/portal/a/c/s/1/acsdisplay.html?DOC=news_service/acs_media_reg_2004.html General information about the meeting is available at: http://center.acs.org/applications/ccs/application/index.cfm?PressReleaseID=2362&categoryid=2...UCSD team determines cellular stress within body is critical
..., and potential cancer therapies. Published in the online edition of the Proceedings of the National Academy of Sciences (PNAS) the week of July 5, 2004, the research in mice provided the first proof that a specific transcription factor, a gene that acts as an "on-off" switch, is essential for normal cell...Combination of gene therapy and gene silencing prevents neurodegenerative disease
...e of Nature Medicine and in the journal's advanced online publication July 4. "This is the first example of targeted gene silencing of a disease gene in the brains of live animals and it suggests that this approach may eventually be useful for human therapies," said senior study author Beverly Davidson, Ph...Crystal structure for anthrax-cell binding complex
NOTE: This paper is being pulished early in an online edition. (La Jolla, CA). A team of researchers led by The Burnham Institute's Robert C. Liddington has determined the crystal structure of the binding complex between anthrax toxin and one of its host receptors. Inhalation anthrax, unless diagnos...JCI table of contents, 1 July 2004
...ins summaries of newsworthy papers to be published online on 1 July 2004, in the Journal of Clinical Invest...s appearing in the same issue and papers appearing online first. A Pregnant Pause for Unexpected Interactions Approximately 1-3% of all couples experience...Cancer gene MYC emerging as key research target
... In an article for Nature Reviews Cancer published online today and in the July print issue, McMahon's research team offers a reanalysis of several previous studies of MYC's binding to target genes. The unexpected discovery that MYC binds to a large percentage of genes without activating them calls into que...Endurance exercise found to be equally effective as diuretics in improving cardiac health
...t. Louis, MO. Their findings are published in the online edition of the American Journal of Physiology Regulatory, Integrativ and Comparative Physiology. The journal is one of 14 published each month by the American Physiological Society ( http://www.the-aps.org ). This study focused on the left ventricl...In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds
...r and Gamble Company. Their findings appear in the online edition of the American Journal of Physiology Regulatory, Integrative and Comparative Physiology. The journal is one of 14 published each month by the American Physiological Society (www.the-aps.org). Methodology The study design consisted of plac...Early dexamethasone exposure has long-term neurodevelopment, neuroendocrine effects
...ne, Tallahassee, FL. Their findings appear in the online edition of the American Journal of Physiology Regulatory, Integrative and Comparative Physiology. The journal is one of 14 published monthly by the American Physiological Society ( http://www.the-aps.org ). Methodology This study is different th...Basic RNA enzyme research promises single-molecule biosensors
...rcher Nils Walter. His latest work was published online in the Proceedings of the National Academy of Sciences June 24. Walter and associates at U-M and colleague Xiaowei Zhuang and associates at Harvard University, use techniques that allow them to study single molecules of RNA enzymes, also known as rib...Oxford Journals takes bold step towards free access to research
...aper has been accepted, and all articles published online are immediately available without charge. ...aper has been accepted, and all articles published online are immediately available without charge. NAR is a highly respected journal, listed by ISI...Kaposi's sarcoma virus 'reprograms' blood vessel cells into lymphatic cells
...ing issue of Nature Genetics and is being released online today. "Our study suggests, for the first time, that Kaposi's sarcoma tumors are derived from blood vessel endothelial [lining] cells that have been reprogrammed by infection with the Kaposi's sarcoma herpes virus," says Michael Detmar, MD, of the ...National Academies Advisory: June 25 UN public briefing on agriculture in Africa
... taped audio file of the meeting will be available online at http://www.un.org/webcast/index.asp ....'Search and destroy' protein turns tables on HIV
...ty report the discovery in a paper to be published online June 24 in the journal Current Biology. In an individual infected with HIV, the virus uses the human cellular machinery to assemble new viral particles. But sometimes those particles contain time bombs: human APOBEC proteins that hitch a ride in the ...Melting ice cap gives urgency to new census of marine life project in Arctic Ocean
...rsity. The project will also consolidate and place online a large body of literature in all Arctic nations, the result of environmental studies of oil and gas exploration. Support will be extended as well to creation of a Russian Taxonomic Centre to help simplify international research. The researchers s...New York City study shows newborns more susceptible to pollution than their mothers
...l published by NIEHS. The full report is available online at http://ehp.niehs.nih.gov/ . Results of the study, the first of its kind in New York City, were released today by the Columbia Center for Children's Environmental Health, part of the Mailman School of Public Health at Columbia University. These fi...Jefferson researchers develop microchip to track genetic signature of cancer and normal tissue
...opment. They reported their findings June 21, 2004 online in the Proceedings of the National Academy of Sciences. Dr. Croce explains that miRNAs are thought to play important roles in regulating gene expression during development and cell differentiation. MiRNAs inhibit the function of their targets, typic...Inadequate vaccines can help breed more vicious malaria strains
...asite Plasmodium in mice. The findings, published online in the open-access journal, PLoS Biology, are likely to spark debate among public health groups seeking to curb the disease, which claims up to two million lives each year and accounts for one child death every 30 seconds in Africa. Vaccines are des...Gestational diabetes not found to alter the metabolic processes in obese pregnant women
...ter, Cleveland, OH. Their findings appear in the online edition of the American Journal of PhysiologyXEndocrinology and Metabolism. The journal is one of 14 published each month by the American Physiological Society (www.the-aps.org). Methodology Fifteen healthy obese women (defined as pre-pregnancy pe...