Oxford Journals takes bold step towards free access to research
...tional customers as well as the NAR author base in order to get this initiative right," commented Richard G...decision, listening to all communities involved in order to respond appropriately in the future." Oxford Journals, a Division of Oxford Universit...Innovative efforts target epigenetics, molecular imaging
...DNA sequences from the individual polonies into an order that reflects the complete sequence of the origina...ce that cost to $1,000 over the next 10 years. "In order to reach that ambitious goal, we will need to develop a completely integrated system that requires v...Biologists ID defense mechanism of leading fungal pathogen
...rganism that doesn't typically infect humans -- in order to find the genes that Candida uses to protect itself against nitric oxide, or NO. Human immune cells give off NO to slow the growth of yeast colonies. The study, published in this month's issue of the journal Eukaryotic Cell, isolated one gene that ...A fly's taste experience is much like our own
...se flies need to know where the food is located in order to react properly," Scott said. "If a fly tastes sugar with its leg, it automatically extends its proboscis and eats. If it detects sugar with its proboscis, it just eats." Scott noted that flies, like mammals, probably also have sour and salt taste ...'Search and destroy' protein turns tables on HIV
...ust be further copied to become double-stranded in order to insert itself into the human genome. The DNA appears to do this without incident, copying the mutations along with the original genetic information. Harris and others have observed that if VIF is not there to interfere, the two APOBEC proteins may...NIH awards grant for cancer research to the University of Wisconsin
...dings on the campus, to work in close proximity in order to collaborate on their research findings. The grant is supported by the National Center for Research Resources (NCRR), a component of NIH. In addition to enhancing opportunities for interdisciplinary research teams, the new facility will permit rese...New public policy & aging report highlights facts and fiction about anti-aging medicine
...niversity urges us to pursue anti-aging agendas in order to "invent a long-lived society in which we can retain our capacities more fully until death." This publication is the first in a series of summer events designed to confront the hope and hype of anti-aging medicine. On June 23, The American Federati...'Mighty mouse' gene works the same way in people
...g for a way to counteract the protein's effects in order to build or rebuild muscle mass. But while research with mice has continued to reveal myostatin's role and the effects of interfering with it, no one knew whether any of the results would be relevant to humans. "This is the first evidence that myosta...Tips from the journals of the American Society for Microbiology
...ous side effects such as abscesses. "In order to combat the disease and mitigate serious clinical complications, research has mainly been aimed at developing efficient vaccines," say the researchers. In the study, mice were immunized with a recombinant subunit vaccine containing parts...Gestational diabetes not found to alter the metabolic processes in obese pregnant women
...tandardize nutritional intake for each subject, in order to maintain weight before conception and allow appropriate increase in weight during pregnancy. The regimen was identical to the diet employed in the treatment of gestational diabetes. All were evaluated prior to conception (P) at 12-14 weeks (E) a...Plant pathologists to discuss the future of organic farming
...ganic farming research and education are needed in order to maintain viable organic farming systems, she said. Because California has the largest output of organic crops of any state, plant pathologists are looking to California's organic program as a model for organic farming programs nationwide. "Plant h...New designed paclitaxel analog kills more cancer cells than natural product
...t picture of the 3-D form that paclitaxel takes in order to bind to tubulin, and "it offers the exciting possibility that now that we know that shape, we can design simpler molecules with a similar shape, which is what we are doing now," Kingston said. The team is optimistic that simpler molecules can be d...Brain development and puberty may be key factors in learning disorders
...xperiments that examine subjects of varied ages in order to determine the developmental course of the characteristic they are studying." Wright and Zecker's research also lends credence to what scientists using MRI and other techniques have discovered about the activity in the teenage brain. Until recent...Protein stops blood-vessel growth, holds promise as cancer therapy
... nutrients and oxygen supplied by blood vessels in order to grow. They also use blood vessels to spread to other parts of the body. This process, known as metastasis, is the most lethal characteristic of cancer and the leading cause of cancer-related death. The strategy of fighting cancer by preventing th...AAAS urges US to give scientists a voice in research misconduct cases
...an expert with no ties to the case under review in order to assist in the evaluation of the highly technical matters presented on appeal." AAAS is uniquely positioned among scientific societies to understand the implications of dealing with technical matters in legal proceedings. Through the Court Appoint...New national research effort needed to secure clean, adequate water supply in coming decades
...a new commitment to research on water resources in order to confront the increasingly severe water problems faced by all parts of the country, says a new congressionally mandated report from the National Academies' National Research Council. In particular, a new mechanism is needed to coordinate water res...Molecule that 'blocks' key bacterial enzyme may lead to new antibiotics
... of thousands of RNAP derivatives, or variants, in order to define the binding sites for MccJ25 on RNAP. The researchers also used biophysical methods, attaching fluorescent tags to MccJ25 and to each of a dozen sites in RNAP. Using the tags, the researchers gauged the position of each bound pair in a GPS-...Researchers make promiscuous animals monogamous by manipulating genes
...in behaviors among individuals within a species in order to better understand the evolution of social behavior....Assisted reproduction can't compensate for waiting too long to start a family
...either natural or artificially aided conception in order to provide efficient family planning advice and more precise information about the potential risks of postponing childbirth beyond a given age. In several European countries the mean age of childbearing is already close to 30 years. "We concentrated ......rmed during the healing and remodeling process. In order to encourage healing, therapies for post-heart attack recovery have focused on enhancing factors that induce new blood vessel growth, but evaluation of the efficacy of these strategies is difficult due to the lack of accurate means to measure the the...