Genes that regulate hearing link humans and fruit flies in new way
...eye development in flies and humans. One promising outcome has been that researchers at UW Medical School are...d at their effects on mated flies," she said. The outcome of the standard genetic pairings was improper development followed by complete failure of the audito...JCI table of contents, 15 October, 2003
...uggests that FGF-2 supplementation may improve the outcome of individuals who suffer TBI following motor vehicle accidents or other brain injuries. The brain can be distinguished from other organs and tissues of the body by its limited ability to repair itself. This lack of self-repair following TBI or disea...Better model of cancer development sheds light on potential angiogenesis target
...elop cancer. Results showed a completely opposite outcome with respect to Id1: all mice with the Id1 gene turned off developed more tumors that also were larger than in previous studies. "Clues to promising cancer drug development are only as good as the model in which you study a process," says Alani. "If...Ki-67 biomarker a strong predictor of outcome for prostate cancer patients
...ce Ki-67 may be a significant predictor of patient outcome for men with prostate cancer treated with both rad...ed Pollack. "The relationship of Ki-67 to patient outcome is a continuous function, wherein the higher the percent of Ki-67, the greater the risk of an advers...Egg-sharing does not damage a donors own chance of a baby say UK researchers
...me is not detrimental to egg sharers and/or to the outcome of recipients' treatment compared with standard IVF or ICSI," said Mr Abdalla. An important additional finding was that there was no evidence to back up a theoretical risk that the donors may have an increased chance of the potentially dangerous cond...ESA and Rosaviakosmos sign up for two Foton flights
The outcome of a year of extensive negotiations, this order will cover the Foton-M2 and -M3 missions, which will have 660 kg of ESA-supplied scientific payloads onboard. The order binds ESA, Rosaviakosmos and two Russian partner companies (KBOM in Moscow, TsSKB...US crackdown on bioterror backfiring
...th material terrorists might exploit. Whatever the outcome of the case (see right), that effort is having repercussions that go far beyond the fate of one scientist. New Scientist has contacted more than 20 prominent figures in the US working in bioterror-related fields. Some refused to talk, and most who d...Computer model offers new tool to probe Woburn toxic waste site
... unique. The plume model also lends insight to the outcome of the Woburn trial, although that was not the scientists only intention. We didnt set out to prove or disprove anyone's trial testimony, Metheny explained. We just wanted to see if we could decipher how and when the chemicals got into the wells. Our......rs Express mission control team will report on the outcome of the spacecraft's delicate orbital insertion manoeuvre. It will take some time for Mars Express to manoeuvre into position to pick communications from Beagle 2. Hence, initially, other means will be used to check that Beagle 2 has landed: first sig...Study suggests new view of gene activation as a dynamic process
...ieve a series of small changes with the collective outcome of turning the gene on. In essence, additions to histones were accumulated until the "on" state was reached. Now, a new study by researchers at The Wistar Institute reveals the gene-activation process through these molecular modifications to be more ...Genes control severity of heart failure, study finds
... with others at Duke to identify genes that affect outcome in patients with heart failure....Proteins may help identify patients who will respond better to treatments in certain cancers
... phenotype is an independent prognostic factor for outcome in the chart head and neck cancer randomized trial...s looked at whether it was possible to predict the outcome of radiotherapy based on these molecular profiles, when compared to more traditional characteristics...New advances in thrombosis help further understanding of disease prevention
...had developed in the veins. The primary efficacy outcome of this study measured the incidence of a venous thromboembolism during treatment. The safety analysis measured all bleeding incidents (major and non-major), thrombocytopenia (decrease in the number of platelets), and death. An independent medical ...Newly identified genes may help predict outcome in childhood leukemia
...hieved long-term remission, compared to an overall outcome of 32 percent of all patients studied. OPAL1 was also highly predictive of a favorable outcome in T-cell ALL, and a similar trend was observed in infant ALL. Low OPAL1 was associated with induct...Use of new direct thrombin inhibitor may be as effective as current standard treatment
... Ximelagatran also was associated with a favorable outcome with respect to major bleeding (1.3 percent versus 2.2 percent) and mortality rates (2.3 percent versus 3.4 percent). Laboratory evaluation showed an incidence of serum alanine aminotransferase (ALAT, commonly measured to assess liver function) elev...Novel approaches to current cellular therapies continue progress toward disease prevention
...nd to be present in the aorta. Another unexpected outcome was a lack of immune rejection after the transplant. Due to the need for multiple, unrelated donor cows during the cloning process, there are slight differences in the mitochondrial proteins of transplanted stem cells from those of the recipient cow...New understanding of why brain cells die after stroke will lead to development of new treatments
...f brain cells after a stroke, and help improve the outcome of patients suffering from a stroke." As the fourth most common cause of death in Canada, and the second leading cause of death in the world, stroke kills about 16,000 Canadians every year. Stroke is a major cause of disability, as peo...B2MIN9: Beagle 2 teams continue efforts to communicate with the lander
...g daylight hours at the Beagle 2 landing site. The outcome of this "blind command" is still awaited. Meanwhile, specialists at the Lander Operations Control Centre continue to investigate other potential reasons for the failure of Beagle 2 to call home, including a possible landing off course, a tilting of...Other highlights in the January 21 issue of JNCI
...als with suitable comparison groups and additional outcome measures. Gene Mutation Affects Sensitivity of Cancer Cells to Chemotherapy Drugs A research team has found that a specific mutation in a gene critical to folate metabolism alters the sensitivity of colon and breast cancer cells to common chemoth...Gene predisposes infants to neurologic injury after heart surgery
...year of age does not necessarily predict long-term outcome for these children," cautioned Dr. Gaynor. "Childr... the National Institutes of Health to pursue their outcome studies in the same children between ages four and five a point at which the researchers will furth...