Could vitamins raise levels of bad cholesterol? Animal study suggests they might
...s from damage caused by diabetes. "In other words, oxidant stress is damaging in some contexts, but probably ...ar disease," he adds, "the previous view that all oxidant stress is bad is probably an oversimplification." In an editorial accompanying the study titled...Study is another step in determining if curry can protect against Alzheimer's
...ntal defensive mechanism for neurons exposed to an oxidant challenge. At the same time, a number of studies have supported the beneficial effects of some commonly used natural products in preventing various pathologic conditions. Spices and herbs often contain phenolic substances with potent antioxidative an...Researchers show absence of key oxygen-sensing molecule leads to developmental defects
... the overall balance of the cell favors a state of oxidant excess, which led us to hypothesize that the mitochondria in the Epas1/HIF-2 knockout mice were impaired. "We attributed the cause of impairment to increased oxidative stress and decreased elimination of reactive oxygen species." To test their hypoth...JCI Table of Contents, September 15, 2003
...ating that estrogen-deficiency sensitizes cells to oxidant signaling and stress by lowering thiol antioxidants in bone resorbing cells. This mechanism provides novel opportunities for the development of potential osteoporosis therapies. TITLE: A crucial role for thiol antioxidants in estrogen-deficiency bone...Fe-TAML(R) activators developed at Carnegie Mellon break down toxic pesticides
... with hydrogen peroxide, or perhaps oxygen, as the oxidant could be spread on fields after a crop harvest to reduce the entry of the pesticides into the groundwater, as well as nearby streams and estuaries. Once they are commercially available, Fe-TAML activators could provide the best available technology f...Study of bacterial enzyme reveals one key to cancer cell survival
...ines whether hydrogen peroxide acts as a dangerous oxidant or as a signal? The investigators propose that the peroxiredoxin enzyme controls the floodgates, keeping resting levels of hydrogen peroxide low, while permitting higher levels for signaling. After studying the enzyme using Oregon State's single cry...Little yellow molecule comes up big
... single bilirubin molecule can take care of 10,000 oxidant molecules, the scientists found. The key is that...their DNA beyond repair, the researchers say. "An oxidant reacts with bilirubin to make biliverdin, which is then converted back into bilirubin by biliverdin ...Ozone produced by antibodies during bacterial killing and in inflammation
...lves. Antibodies do this by producing the chemical oxidant hydrogen peroxide--best known as the foamy formula... biology. "All our analytical data point to this oxidant possessing the chemical signature of ozone," says Wentworth, "in which case, this is a new molecule ...Slightly stressed carp succumb easily to parasite
...uce an excessive amount of nitrogen monoxide. This oxidant is toxic for the majority of intruders, including the parasite. However, the carp produces so much that the cells which must clear up the intruders are weakened. The parasite can then reproduce unhindered. The vast majority of carp, more than 90% of ......tract totally protected the coronary arteries from oxidant injury. Extracts from bilberry and elderberry prov...ided partial, but not complete, protection against oxidant injury. Conclusions Berry extracts, in concentrations likely to be seen in the human blood stream fo...Eat your veggies: Indirect anti-oxidants provide long-term protection
...om becoming carcinogens. Not previously considered oxidant fighters, the enzymes have the ability to detoxify... the amount of sulforaphane as well as the type of oxidant and its amount. "This adds to already good evidence that eating large quantities of vegetables -- an...Worlds largest scientific society convenes regional meeting June 14-17 in Seattle
...acific Northwest — Problems of aerosol and oxidant formation near population centers along the coastal mountains will be discussed. Other topics include effects of windblown dust on human health and air pollution from Asia and Canada to the United States. (Leonard Barrie, Global Environmental Change...UNC-CH experiments reveal new 'pen' can disinfect water
...ative pen cell designs also were tested by seeding oxidant solutions generated from the pen with test microbes, including highly chlorine-resistantCryptosporidium parvum, a major source of contamination in water. "There was dramatic -- more than 99.99 percent -- reduction of all test bacteria and viruses wi...Battery-operated pen quickly disinfects drinking water
...tive pen cell designs were tested by seeding mixed oxidant solutions generated from the pen with test microbes, including highly chlorine-resistant Cryptosporidium parvum, and measuring the inactivation that occurred over time. There was dramatic (>99.99%) reduction of all test bacteria and viruses withi...Common enzyme deficiency may jeopardize pregnancies
... anti-epileptic drug in North America. Phenytoin's oxidant effect is comparable to that of many other drugs a...estruction of red blood cells in adults exposed to oxidant drugs like antimalerial agents. There have been no investigations of the impact of the hereditary co...Study: avoiding vitamins A, E might improve cancer therapy
...nificantly reduced in size because of induction of oxidant stress due to what arecommonly called free radicals in the brain tumors," Albright said. "Higher levels of cell death wasrestricted only to the brain tumors, while normal tissues were not affected by depletion ofantioxidants in the mouse diets." In ...Concern Unfounded About Damage From Vitamin C
...l ions such as copper or iron in thepresence of an oxidant such as hydrogen peroxide," said Anitra Carr, a researchassociate with the Linus Pauling Institute. "Some scientists, including onestudy that got international attention last year, have hypothesized that thesame thing may be possible in animals. ...Study Ensures Effective Ways To Measure Macular Pigment Density
...nt epithelium. In addition, carotenoids may limit oxidant stress resulting from metabolism and light, acting as antioxidants. In this study, serum concentrations for lutein, zeaxanthin and beta-carotene were measured by HPLC, and MPOD was measured by heterochromatic flicker photometry. Dietary patterns a...UF Researcher Finds Way To Slow The Aging Process
...One of the mechanisms that causes this isincreased oxidant production, in a process known as muscle oxidation. Regular exercise or anti-oxidant supplements could potentially improve and protect against this oxidative stress, which may have direct implications on tissue loss and the aging process." ...New Evidence Points To Role For Free Radicals In Alzheimer's Disease
...eimer's disease. Althoughinflammation is linked to oxidant stress and its associated tissue damage, itwould b...tory component, and inflammation isassociated with oxidant stress," says FitzGerald. "So, it becomes relevantwhether drug targets associated with inflammation ...