Tag: "pancreas" at biology news
Two Long-sought Diabetes Gene Found
...be important in the insulin-secreting cells of the pancreas
and thus was overlooked in the search for diabetes genes. There are other genes in this pathway in addition to HNF-1-alpha and HNF-4-alpha. Genes from this family have become leading candidates for other forms of MODY as well as common late-onset NID...
Insulin Resistance Is A Risk Factor For Atherosclerosis In Whites And Hispanics
...ulin resistant. Insulin is secreted by the pancreas
and processes glucose in the bloodthat is produced...ucose in their blood.After a while, he said, their pancreas
simply "wears out" and they becomediabetic. Currently there is no easy way to test for insu...
Overfeeding Normal Infant Rats Affects Three Generations: Permanently Changes Basic Metabolism, Interferes With Reproduction
...ce a stress onthe pancreas. When this happens, the pancreas
sometimes can't produce enoughinsulin, a hormone that allows the body to use carbohydrates, triggeringgestational diabetes. Taylor says newborn rats are immature at birth so their first threeweeks of life correspond to that of a human fetus ...
15 Drugs, Dyes And Other Chemicals Newly Listed As Known Or Likely Human Carcinogens
...d to treat cancers of the stomach, largeintestine, pancreas
and lung; melanoma; and multiple myeloma. DANTHRON, or dantron, a laxative removed from the market several yearsago when tests were published indicating it caused cancer in laboratoryanimals. It is also an intermediate in the manufacture of dyes. 1,...
Mice Lacking The Pax8 Gene Suffer From Hypothyroidism And Fail To FormThyroxin-Producing Cells Of The Thyroid Gland
...e generation of specific cells in the pancreas
(Sosa-Pineda, B., Chowdhury, K., Torres, M., Olive... and Gruss,P., Nature, vol. 387, 22 May 1997). The pancreas
is composed of two major cell types: the exocrine cells or acini, produce digestive enz...
How A Common Protein Becomes A Cancer Killer
...t ribonuclease A - a digestive protein made by the pancreas
-could be genetically altered to kill cancer cells. The finding opens a door tocreating a new class of "natural" drugs aimed at fighting cancer, without theside effects of standard chemotherapy, he said. "The greatest advantage could be as a potentia...
Debilitating Pancreatic Disorder Linked To Cystic Fibrosis Gene
...se ducts normallydeliver digestive juices from the pancreas
into the small intestine. It isthought, Cohn said..., and that the pain felt by patients is due to the pancreas
digestingitself. While the genetic findings in this study provide clues about the earlyevent...
Researchers Identify And Isolate First Gene For A Form Of Insulin-Dependent Diabetes
...egene cause insulin-secreting islet b-cells in the pancreas
to die prematurely.Therefore, Permutt believes the protein involved may play a role in more commonforms of diabetes. "The gene encodes a large, unusual protein that appears necessary fornormal survival of islet b-cells," he explained. "Whe...
Life In Womb Determines Adult Health
...may eventuallysuffer diseases of the heart, liver, pancreas
and kidneys because those organswere incompletely ...d liver that can't properlyregulate cholesterol, a pancreas
that will lose the ability to produce insulinor a heart predestined to disease. As Nathanielsz puts ...
Powerful Anti-AIDS Agent Found In Tears And In Urine Of Pregnant Women
...cken egg white aswell as ribonuclease found in the pancreas
of cows. All of these proteinsinhibited HIV and were incredibly potent. Dr. Lee-Huang and Dr. Chen's colleagues in this study are Yongtao Sun of NYU School of Medicine; Philip L. Huang and Paul L. Huang, currently at HarvardMedical School; Hsia...
Fighting diabetes: UD researchers move closer to chip-based control of 'smart,' implantable insulin pumps
...plified to approximate thefunction of the gut, the pancreas
and other portions of body systems, they couldbe maintained on a tiny computer chip, Doyle says. His approach, based on "model predictive control with state estimation" (MPCSE)algorithms, effectively reduced peak glucose levels by 44 percent, in comp...
Genetic resistance to chemically-induced diabetes in mice linked to elevated antioxidant levels
...thionereductase, and glutathione peroxidase in the pancreas
and other tissuessystemwide. A controlled cross between the ALS and ALR strains resulted in all F1offspring of both sexes exhibiting resistance to alloxan-induced diabetes,suggesting that the unusually high free radical defense trait in ALR m...
New technique builds microscopic medical devices for transplants
...to recognize cells in the pancreas
that respond toglucose and produce insulin. One possible therapy is to transplanteven just a few grams of healthy pancreatic cells, Ferrari explained. A capsule containing the...
UF researchers screen newborns for genetic susceptibility to diabetes in effort
to find causes and cures
...hite blood cells mistakenly destroy thepart of the pancreas
that produces insulin. The result is an impaired ability touse and store sugar and other nutrients for energy. Complications include heartdisease, stroke, blindness, kidney failure and poor circulation. Families of infants born at the UF-affiliated S...
Stem cells may be powerful gene shuttle
...se the cells to genetically "remodel"heart, liver, pancreas
or brain tissue, theorize the scientists. And ifhematopoietic stem cells can be manipulated to produce organ-specific cells,they may one day prove to be a better source of therapeutic cells than thedamaged organs. Mulligan's and Kunkel's collaborato...
Scientists uncover possible cause of colitis
...Academy of Sciences (PNAS). Inflammations of the pancreas
and skin also appear to be aggravated andcontrolled by the NEP/substance P cycle, Bunnett said, and these too may betreatable with substance P blockers. Current first-line treatments for inflammatory bowel disease often have limitedeffect or carry se...
University of Pittsburgh research may lead to new therapies for diabetes
...glucose in the blood for energy because either the pancreas
cannot make enough insulin or the insulin that is available is not effective. Islet cells, located in the pancreas, make and secrete hormones that help the body break down and use food. Beta cells are located in the islets and make and release insu...
Possible cause and treatment for shock uncovered by UC San Diego bioengineers
...or the source of the cell activators. "The pancreas
produces potent enzymes that can digest any tissueeven our own. These enzymes are regularly released into the intestines to digest our food," said Schmid-Schoenbein. "Our theory is that when blood pressure falls sharply in the intestine, pancreatic...
Honey may be the ideal pre-workout energy source
...s a measure of how much insulin is released by the pancreas
in order to "process" the sugar just consumed." In addition to the research presented today, future studies will examine the effects of honey in comparison to different types of carbohydrate gels prior to weightlifting exercise. These studies, focus...
JDF awards $10 Million to Children's Hospital of Pittsburgh and University of Pittsburgh for new research center to help speed diabetes cure
...or young patients. Islet cells are located in the pancreas
and produce insulin. In people with Type 1 diabet...osed in childhood. In Type 1 diabetes, a person's pancreas
produces little or no insulin. Although the causes are not entirely known, scientists believe the b...
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