Researchers discover genetic basis of heritable sleep disorder
...n blue eyes.A brown-eyed (Bb) and a blue-eyed (bb) parent will, on average, have 50 percentbrown-eyed and 50 percent blue-eyed children. In fact, in the three families that Jones and Ptácek studied, half thechildren of the afflicted parents had the disorder, a classic Mendelian patternof inheritance...DNA fingerprinting reveals surprise in wine-grape family tree
...em were probably the offspring of the same pair of parent varieties-- Pinot and Gouais blanc. A further sta...versity," Meredith said. Identification of the two parent grapevine varieties provides useful information to grape breeders, she added. "We now know that you'...Pinpoint targeting promises improved success in gene therapy for blood and other disorders
...y succeeded in correcting theprotein defect in the parent cells by inserting healthy genes into DNA with the...rdous effect onother cells. "We target the parent stem cells because we want the therapy to last fora long time in humans," Wilcox said. "That wouldn'...Scientists discover second gene for disorder described by Darwin
...fmutation would require a defective gene from each parent in order to produceabnormal development. However, if the mutation affects the internal portion,the result is similar to the "one bad apple spoiling the barrel" phenomenon. The defective piece of protein inside the cell could bind up functional siste...Duke scientists reverse a rare form of muscular dystrophy in mice using gene therapy
...elopment company inResearch Triangle Park, and its parent company, Synpac Pharmaceuticals Ltd. ofCambois, England. The company is funding an on-going clinical trial to test theenzyme therapy in up to three infants at Duke. The research is also supported bythe Howard Hughes Medical Institute and a gift from ...SIDS prevention tactic leads to epidemic of 'misshapen head' in infants
...his head is gorgeous," she said with relief."Every parent wants their baby to be perfect, and I was so afraid he'd bedeformed." Tony and Susan Avallon, also of Culver City, faced similar concerns when twinsPerris and Quinn displayed signs of the condition. At four months, both babieshad noticeable flattenin...Birds beware! Pinecones armed and dangerous
...nd that pine cones, which bear theprogeny of their parent tree, have evolved highly specialized ways to ward offpredators, ensuring the dispersal of their seeds. The study, published in the June issue of Ecology, focuses on the evolutionaryimportance and modern function of spine development in pine cones. ...Genetic testing of pregnant women with liver illness could save infant lives
...o inherit one copy of the defective gene from each parent inorder to develop the disease. A mother who carries just one defective copy ishealthy until she becomes pregnant with a baby who has inherited the mutatedgene from both parents. AFLP occurs in approximately one in every 14,000 pregnancies. S...Research Bears Fruit, And Patents
...t "Harry is the anchor of our group. He hybridizes parent plantsthat may contribute desirable traits -- such as fruit quality, diseaseresistance, and winter hardiness -- to progenies of seedlings that all of usevaluate for adaptation to our different climates and growing conditions." Swartz and colleagues p...Compounds From Fruits, Vegetables And Grains Slow The Growth Of Human Tumor Cells
... morethan 22,000 compounds. All are derived from a parent compound called mevalonicacid. Limonene and lycopene are examples of isoprenoids that inhibit cancer. Many isoprenoids contribute to plants' distinctive flavors and fragrances, Elsonsays. In plants, isoprenoids help regulate germination, growth, flow......ersityCorporation for Atmospheric Research, NCAR's parent organization, isoverseeing operations from its support office for logistics and datamanagement, headed by Richard Dirks of the UCAR Office of Programs. Thehighly instrumented C-130 aircraft will be based through March 27 atMale' airport, which occupi...In The Genes: Extra Belly Fat, Insulin Resistance Linked
... that plays a role in a disease will pass from the parent with the geneto some of the couple's children. By ...ikelihood, the investigators looked at how often a parent with insulinresistance had a child with extra belly fat and vice versa. If the same geneticfactors f...Gene Identified For Heart Defect That Causes Sudden Death In Young People
...on needs to inherit a defective gene from only one parent todevelop the disorder. Children and young adults with ARVD have a 2.5 percentchance of dying in any year. The disease is difficult to diagnose. Often, the first symptom of ARVD isdeath, triggered by erratic heartbeats called arrhythmias. Those wh...Biochemical Markers Could Help Identify Battered Children
...wly in the brain, its presence may reveal whethera parent is lying about the timing of the injury. High levels might alsoindicate prior injuries, signalling a history of abuse. Kochanek and his colleagues could find no trace of quinolinic acid incerebrospinal fluid taken from 39 adults with head inj...When Genes "Breed" In The Lab, A Suprising Number Of Their Offspring Are Supergenes
...Now its potential is beginning to be realised. The parent genes arefirst broken into fragments by shattering their DNA with ultrasound, or cuttingthem up with an enzyme called DNAse. They are reassembled into daughter genes,comprising fragments from several parents, using a variant of the DNA-buildingpolyme...Wisconsin Scientists Culture Elusive Embryonic Stem Cells
... ofhuman embryonic stem cells - cells that are the parent cells of all tissues inthe body. The achievement has profound implications for transplant medicine, drugdiscovery and basic developmental biology. It opens the door to growing fromscratch everything from heart muscle to bone marrow and brain tissue. ...Ribozymes To The Rescue: New UF Gene Therapy Shows Promise For Treatment Of Inherited Blindness
... that is, they inherited a defective gene from one parent who has the disease, but also received a normal gene copy from the other parent. (About half the cases of retinitis pigmentosa occur with no known family history.) The UF research targets the autosomal-dominant form of the disease in rats. "We desi...School Breakfast Participation Leads To Academic, Psychosocial Improvements
...dents; of those, psychosocialdata from student and parent interviews was available for 85 students. Inaddition, teachers in the Baltimore schools completed evaluations of studentbehavior before and after the free breakfast program, providing information on76 of the study-group students. Even before instit...Researchers Discover The Pattern Of Inheritance Of Non-Chromosomal DNA
... equal amounts of DNAto their baby -- almost. Each parent donates one chromosome from each of the23 pairs humans have. But all cells also contain thousands ofnon-chromosomal DNA molecules located in small energy factories calledmitochondria. And only mitochondrial DNA (mtDNA) from the mother passes tothe fe......e ethanol from plant material than its unmodified parent yeast or any other yeast. Nancy Ho, group leader for molecular genetics and the lab's senior research scientist, holds cultures of the new yeast strain (in the petri dish) and a sample of ethanol. (Purdue News Service Photo by David Umberger) ...