Tag: "partial" at biology news

International study findings link acne-like rash to effectiveness of new targeted cancer treatment

...ubject of research. "We saw independently reviewed partial tumour responses in 12% of patients and a median survival time of 6.6 months," he said. "In total, 87% of patients developed this acne-like rash. Of the 46 patients who did not develop a rash none had a tumour response and their median survival was o...

Award winning researchers reveal potential new role for Glivec

... response confirmed by tumour assessment. Four had partial response followed by surgery to make them free of ... profile. One, with a translocation t(17-22) had a partial response to imatinib but the disease progressed after seven months of treatment. The other did not h...

Tracing genes, biologists show lizard migration is traced to Florida

... any problems for people, except for those who are partial to the green lizards and miss seeing them so much." The genetic changes occurring in the Florida populations are happening at a much quicker pace than that of typical Darwinian evolution tens of years versus up to millions. That has caused...

New sequence involved in DNA replication timing may aid in cancer detection

...ffect on replication timing, two copies produced a partial effect, and three copies caused replication to occur in late S phase. The researchers confirmed this finding by removing the LCSs from a late-replicating origin to convert it to an early-replicating origin. "Interestingly," noted Huberman, "in many c...

Tips from the Journals of the American Society for Microbiology

...h are generally long and tedious, and allow only a partial inventory of the bacterial microflora," say the researchers. "New molecular approaches based on direct analyses of DNA (or RNA) in its environment without microbial enrichment have allowed for precise descriptions of microbial dynamics in complex ec...

Brain has center for detecting sound motion

...he researchers, such improvement likely was due to partial recovery because of adaptive changes in her cortex. According to the researchers, their findings "provide evidence of an auditory motion module within the right posterior STG" and that by analogy with the motion-detection region of the visual system ...

Protein is key for digestive function of the pancreas

...blood levels of digestive enzymes and demonstrated partial resistance to pancreatitis. This suggests that VAMP8 may be involved in the abnormal secretion of digestive enzymes associated with pancreatitis. Further research is needed to establish whether VAMP8 is directly linked to pancreatitis....

Forgetting, reminding, and remembering: The retrieval of lost spatial memory

...new one. And that's what happened to the rats with partial lesions. Testing rats with partial damage to the hippocampus, they showed that the resulting memory impairment was not a result of stor...

Physics gravity model applicable to disease spread

... to adult populations and to populations that have partial immunity." The researchers are working with the National Institutes of Health John E. Fogerty International Center for Advanced Study in the Health Sciences. Influenza is one adult disease the group is studying but is a difficult one. Influenza, a...

Activated signaling pathway may predict lung cancer patients' response to gefitinib

... disease control rate (which includes complete and partial responses and stable disease), and time to progression than patients with P-Akt negative tumors. There was no difference in outcome according to MAPK phosyphorylation (P-MAPK) status. P-Akt positivity, but not P-MAPK positivity, was associated with a...

Research reveals role of gene in infertility

...fects in human reproduction may be associated with partial loss of the RAD51 function," Ma says. "While it is not possible at present to study defects in this RAD51 gene in people who have fertility problems, we now can use this mutant plant strain to understand more than we could before about its role in s...

Why some neonates need caffeine

..., decrease the number of apneic spells, and reduce partial tension of carbon dioxide (PCO2) and the need for (and duration of) mechanical ventilation. Peripheral chemoreceptors, found in the carotid and aortic bodies and stimulated by chemical changes in blood composition, provide feed-forward control of re...

Gene profiles could improve acute leukemia diagnosis and lead to better treatments

... which type of white blood cell gave rise to it. A partial duplication of the MLL gene resulted in a completely different gene signature than the one caused by the MLL chimeric fusion gene. This suggests that the two different mutations of the same gene cause AML by two different mechanisms. "Our ability t...

Endurance exercise found to be equally effective as diuretics in improving cardiac health

...raining of mild-to-moderate intensity can induce a partial regression of LVH with reductions in LV mass index...moderate intensity exercise training can result in partial regression of increased LV relative wall thickness and LVH that is similar to the effect induced by ...

Growing replacement teeth and dental tissues

...novel regenerative therapies which seek to restore partial tooth tissue loss. Such approaches provide potential for restoration of the structural integrity of the dental tissues where the new tissues become an integral part of the tooth, thus minimizing some of the problems of restoration failure with tradit...

Parting genomes: UA biologists discover seeds of speciation

...all of the resulting hybrid sons are sterile. This partial capacity for interbreeding, Reed says, suggests that these flies are on the verge of evolving to become completely separate species. Another finding adds support to that notion. Researchers had previously reported that for one strain of D. mojavensis...

Novel therapeutic bortezomib moves to phase II trial in lung cancer patients

...a similar schedule. Out of 12 patients, four had a partial response and seven had stable disease. In the larger phase II trial, which will enroll 99 patients, the drugs will be given sequentially, with bortezomib following the chemotherapy drugs. Preclinical research at UC Davis Cancer Center suggests that ...

Researchers target deficit irrigation for wine grapes

... also tried a deficit irrigation strategy known as partial root zone drying, which originated in Australia. With partial root zone drying, irrigation water is alternately applied to only one-half of a vine's roots. "We t...

Domesticated tree crops may be the 'future of forestry'

...wild." Meilan said he sees tree domestication as a partial solution to the myriad problems associated with human population growth, such as loss of agricultural lands, encroachment on wildlife areas and increased consumption of natural resources. "I'm not suggesting that we have genetically engineered trees ...

Insulin-producing pancreatic cells are replenished by duplication

...rocess of renewal or during regeneration following partial removal of the pancreas were generated from pre-existing beta cells. According to Melton, the finding highlights a largely unappreciated capability of beta cells. "No one has really paid much attention to the replicative capacity of the beta cell," ...

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