JCI Table of Contents, September 15, 2003
...astating consequence of a loss of kidney mass. The partial loss of kidney mass triggers the compensatory growth of remaining nephrons. In some cases, this compensatory growth becomes excessive, resulting in renal lesions and end-stage renal failure. The transcription factor AP-1 is composed of Jun and Fos pr...Non-judgmental intervention may help binge eaters overcome disorders
...disorders, 90 college students who met the full or partial diagnosis for these two disorders were recruited. The subjects were predominantly female (88 percent) and white (60 percent) or Asian/Pacific Islander (29 percent). On average, participants were of normal weight, but 95 percent of them reported a de...Researchers identify second gene responsible for rare syndrome associated with skeletal defects
...ions including a body-fat disorder called familial partial lipodystrophy, muscular dystrophy, cardiomyopathy and a premature aging disorder called progeria. "It is likely that minor changes in these genes may predispose individuals to premature aging, a change of body-fat distribution, as well as osteoporos...Natural hormone could reverse heart damage
...tin infusions had a complete reversal of LVH and a partial shrinkage of enlarged heart cells, whereas the mice on caloric restriction had no change in LVH and a smaller reversal of the enlarged heart cells. So are leptin infusions headed to your doctor's office? "It's unlikely," Barouch says, as humans pr...Finding dirty bombs and other radiation threats
... variety of radiation detectors and monitors. With partial funding from the Department of Homeland Security (DHS) and NIST's Office of Law Enforcement Standards, NIST researchers are investigating a wide variety of detection devices, ranging from 3-meter-high portal towers that scan truck trailers while they...Animal studies show CA4P suppresses development and induces regression of ocular neovascularization
...l neovascularization. However, CA-4-P also caused partial regression of established CNV, a finding that sets...reatment that has been shown conclusively to cause partial regression of CNV, and therefore CA-4-P is in select company. Therefore, similar to PEDF gene trans...Wildland fire impact on watersheds: A special conference of the Geological Society of America
...e held at the Sheraton Denver Tech Center Hotel. A partial list of participating organizations includes the International Association of Wildland Fire, the USDA Forest Service, the U.S. Geological Survey, the American Water Works Association, and The Nature Conservancy. The meeting program will focus on geo......re energy can be diverted to fueling flight. This partial atrophy of their digestive system affects birds when they stop to feed at sites along their migration route. McWilliams says that because their digestive system is shut down, the birds must eat less until their gut becomes acclimated and can operate...Researchers identify clotting protein which causes hepatitis B
...esult from coagulation of the blood, and may cause partial or complete blockage of a blood vessel. This deprives the tissue of normal blood flow and oxygen, resulting in damage or death of the tissue. Corona viruses are named for their corona-like (halo) appearance in electron micrographs. They account for ...Novel bacterium detoxifies chlorinated pollutants
...t decade in understanding the bacteria involved in partial degradation of PCE and TCE, this study represents a significant advance, researchers said. "Isolating this bacterium will allow us to study the organism and the dechlorination process in more detail," said lead researcher Frank Loeffler, an assistan...How plants get made in the shade
...every plant in that field is triggering at least a partial shade-avoidance response," she said. "It's causing a depletion of biomass, which is what we eat if we're eating the plant itself. And because of the premature flowering, it can significantly impact yield, if it's the seeds or grain that's harvested."...Brain cells seen recycling rapidly to speed communications
... observed a series of abrupt and lasting -- albeit partial -- decreases in fluorescence, indicating multiple fusion events. Yet, only rarely was there a full loss of fluorescence, indicating full classical collapse. "A likely explanation is that most fusion events were simply too brief to permit dye to esc...KEPPRA international Phase IV SKATE study results show favourable efficacy
...IV trial), show a high proportion of patients with partial onset seizures experienced an overall significant ...s 1 . This efficacy was confirmed across different partial seizure types 1 and in addition, the results also showed a substantial seizure freedom rate of 17.2...Insulin-degrading enzyme may affect risk of Alzheimers disease
...s amyloid-beta peptides. Most importantly, even a partial decrease in insulysin activity was found to raise amyloid-beta peptide levels in the brain. High levels of the peptides increase the risk of Alzheimer's disease, which affects more than 4 million Americans. "It identifies another pathway that's impor...Tissue engineering for erectile dysfunction?
...through tissue engineering. "Right now we can do partial penile repair, but in order to do complete replacements, we need to make sure all the parts are there, including the nerves," Atala said. "This research takes us one step closer." Future work will attempt to tissue-engineer a complete penis, growing...Bread mold yields a genome first for filamentous fungi
... in suppressing the creation of these new genes or partial genes" and it may have"virtually arrested" the further evolution of Neurospora. According to Maryanna Henkart, director for NSF's Division of Molecular and Cellular Biology, the evolution of the Neurospora sequencing effort itself has been driven by ...Researchers identify gene for premature aging disorder
...h disorder type 2B1, the Dunnigan type of familial partial lipodystrophy, mandibuloacral dysplasia and a familial form of dilated cardiomyopathy. Prior to coming to NIH to lead the Human Genome Project in 1993, Dr. Collins had established a reputation as a relentless gene hunter using an approach that he nam...Smart mathematical model prevents the spread of swine fever
Dutch epidemiologists have calculated that partial vaccination can stop outbreaks of swine fever. Wha...sity. PhD student Don Klinkenberg calculated that partial vaccinations do not exceed the limit for the outbreak of an epidemic. If the mother sows are not vac...Researchers find possible link between pre-natal alcohol consumption and diabetes
...at prenatal ethanol exposure in rats can lead to a partial central diabetes insipidus evident in the young adult. This is supported by the observations that pre-natal ethanol (PE)-exposed rats drank twice as much water, had reduced pituitary content of AVP, a 50 percent reduction in the genetic material in ...Cholesterol lowering drug effective in treating most common form of multiple sclerosis
...ch symptoms or attacks are followed by complete or partial disappearance of the symptoms until another attack occurs. Attacks may remit for weeks, even decades, between relapses. Currently, the most common medications used to treat MS are interferons, a class of drugs that interact with or regulate the body'...