1996-1997 Human Genome Lecture Series
...cs, and issuesassociated with genetics research in particular populations. All lectures takeplace from 11:30am - 1:00 pm in the Lipsett Amphitheater, Clinical Center. Theschedule follows: October 15, 1998 Stephen O'Brien, Ph.D. National Cancer Institute Comparative Anatomy of the Mammalian Geno...Cricket And Chemistry Combine To Provide New Understanding Of How Fats Work
...een to the "leg stump "and "off stump" chains in a particular fat and thus allow industrial chemists to both monitor and model the effect of particular enzymes on various fats. The research team is using a novel Nuclear Magnetic Resonance approach to......d toseek out and destroy the mRNAs associated with particular diseases -- or themRNAs associated with resistance to specific drugs. In fact, an EGS already hasproved effective against hepatitis in animal experiments at Innovir LaboratoriesInc., which has an exclusive license from Yale to develop Professor Altm...Evolution Re-Sculpted Animal Limbs By Genetic Switches Once Thought Too Drastic For Survival
...to where they lie in the body. In the case of that particular fly mutant, if the homeotic gene calledAntennapedia is turned on in the head segment, "the cells that bud off from thefly's head think, 'oh, we're sitting in the thorax, we're supposed to grow intoa leg,'" Patel explained. In crustaceans, if Ubx-abdA...New Gene May Intensify Breast Cancer Growth
...reast cancerthat emphasizes the importance of this particular kind of gene to the growth ofcancer cells in a significant number of patients. And that's going to be anextremely interesting thing to investigate." Previously, other genes found to be amplified in breast cancer have led toclinical tests and trials o...Vitamin C Deficit Linked To Skin Disease
...s to anunderstanding of how vitamin C behaves in a particular disease." It is still unclear whether a deficiency of vitamin C is a contributing cause ofthe disorder or one of its effects. PCT is the most common form of porphyria, a group of disorders that causeschemicals called porphyrins to accumulate in the ...Female Fireflies Lure Males For Defense Chemical
...he 1970s showed that certain birds -- thrushes, in particular -- are repelled by fireflies with the lucibufagins, the Cornell scientists noted in the PNAS article. Lucibufagins may deter ants, other types of spiders and even predatory bats, they speculated, adding that the chemical also protects firefly eggs. ...Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
... points out. "It was previously found that this particular combination of altered genes is significantly lower in human tumors--our results may suggest why that is the case. These are two of the most commonly altered genes in colorectal cancer and understanding their mechanism in carcinogenesis i...Early Menarche Puts Young Girls In Peril
...tion from the l9th to 20th century, however, is of particular interest to American psychologists. Brumberg calls for a new era of "girl advocacy" in which multigenerational dialogues on sexual ethics would better prepare girls in ways that go far deeper than the simple maxim, "Just say no." As a social "intimat...Pea Plant Stem Growth Gene Cloned
...n enzyme that adds a hydroxyl (HO) group at a very particular location onto GA20, which is the is the immediate precursor of GA1. In the dwarf plants there is a change of one base in the DNA sequence, which leads to a change of one amino acid in the resulting protein. In turn, this results in an enzyme that is...Molecular Piracy Turns Protein Into Traitor
...nd a molecule with the desired properties. In this particular case, the virus was hunting for a molecule that would prevent an inflammatory immune response that might clear the virus. "The hope is that by understanding how the virus made this antagonist, we will learn lessons which will help us in the design o...Study Sheds Light On Behavior Of Middle-Age 'Undertaker' Bees
..."We didn't find any evidence for learning for this particular task,"Trumbo said. "This rules out one of the major hypotheses that hasbeen put forward for middle-aged specialization: That social insects willget better and better at what they do." Previous research had shown that learning is important for the ...New Description Of Protein May Be Basis For Regulating Cholesterol
... block - acommon plant alcohol derivative - into a particular product. In this case, theproduct is a terpene mol...ith unique structures. "If we can understand how a particular proteinis designed and works and how pieces of its system function, then in principlewe can make des...Imaging Studies Illuminate Brain's Response To Cocaine
...tter of turning certain structures on to produce a particular response. Instead the patterns of which areas are activated in what sequence and for howlong seem to determine the feelings generated, particularly in the case ofcraving. "Our observations regarding the nucleus accumbens were probably the mostunexp...Bowman Gray Scientists Find Novel Way To Block AIDS Virus
...cribes how acritical co-receptor on the surface of particular white blood cells calledlymphocytes is blocked, making the cells immune to infection by HIV-1. HIV-1 virus causes AIDS by invading and destroying the white blood cellswhose functions are essential to maintain the human immune system. ...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
... which is affiliated with the college. Of particular importance, he noted, was the strong relationship between protein levels and the amount that the cancer spread. "We not only found the confirming relationship between aggressiveness of the tumor and decreasing Rb2 protein, but also with...Limits Of Life On Earth: Are They The Key To Life On Other Planets?
...deep rocks by conducting intensive research at one particular South African gold mine. Microorganisms may lie, Lazarus-like, viable but entombed in ice sheets and ice caps of the Tibetan plateau, the South American Andes, and the north and south polar regions. A project by Lonnie Thompson and Ellen Mosely-T...Growth Factor Stimulation Leads To Increase In New Neurons In The Striatum And Cortex Of The Brain
...e stimulated to produce newneuronal cells in these particular parts of the brain raises new hope thatsomeday these cells will be valuable in treating neurological diseases includingHuntington's disease, Parkinson's disease, and Alzheimer's disease. If thesecells differentiate into neurons they would synthesize ...Husband-And-Wife Team Embarks On Search For Genes Linked To Schizophrenia
... will try to determine how often the illness and a particular gene, or genes, are seen together. If we can find the gene that causes the illness and then find the product of that gene, we can begin to design more effective treatment." About 1 percent of the world's population is afflicted with schizophren...Colorado State Scientists Tackle Genetic Makeup Of Obscure Bacteria
...ringthe bacteria to develop into a disease in this particular group of people." Although Mycobacterium avium belongs to the same family of well-studiedbacteria that cause tuberculosis and leprosy, not much is known about how itinteracts with cells or why it can grow to such large numbers in the bodywith...