AIDS vaccine study harnesses 'killer' immune cells to control virus, prevent disease in animals
...M.D., the paper's senior author and chief of viral pathogenesis at Beth Israel Deaconess. "However, the findings in this study suggest that a vaccine might slow disease progression after an infection has occurred and decrease the likelihood of an infected individual transmitting the virus. This could have importa...Team identifies first drug therapy for rare, precancerous stomach illness
...le to implicate a pathway that is important in the pathogenesis of a human disease." First described in 1888, Mntrier's disease is quite rare. Only 300 cases of what Coffey describes as a "fascinating disease" have been described in the scientific literature, he said. However, Coffey noted that the study of rare......Ph.D. program. For his thesis, Lauring studied the pathogenesis of feline leukemia virus, which serves as a model system for both human cancer and AIDS. Knowledge of how the virus causes feline leukemia could provide clues to how HIV, a similar virus, causes human AIDS. Lauring is from St. Petersburg, FL. E...Tips from the Journals of the American Society for Microbiology: March 2001
...merson, T. toth and X.J. Meng. 2001. Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human. Journal of Clinical Microbiology, 39: 918-923.)...Malaria research and training benefits global community
...pport research in malaria-endemic countries on the pathogenesis of severe malarial anemia. More information about this program, which is currently accepting applications, is available on the FIC website at http://www.nih.gov/fic/programs/malaria.html . Information about NIAID malaria research activities is ava...MelTec GmbH announces new technology for High-Throughput Topological Analysis of human cells
...vasion of the artery wall is an early event in the pathogenesis of arteriosclerosis. According to the study, the NCDS is capable of detecting and monitoring at least 85% of the cells involved in tissue migration and the protein networks that participate in the involved mechanisms. This newly available data is co...Hammering out the role of IDX1 in diabetes
...the absence of Idx1 mutations, could contribute to pathogenesis . Indeed, IDX-1 expression is reduced in hyperglycemic animals, but it has not been clear whether this change is a cause or a consequence of the progression of diabetes. To test this matter directly, Thomas et al. placed a hammerhead ribozyme speci...Lymphocytes in early atherogenesis
...r studies that examined the role of lymphocytes in pathogenesis in the ApoE-deficient strain, another widely studied atherosclerosis-prone model. Song et al. argue that their system more accurately matches human pathogenesis, in part because ApoE-deficiency (but not LDLR-deficiency) leads to impaired innate immu...Mouse model of type 2 diabetes
... an extremely useful model with which to study the pathogenesis of type 2 diabetes, and test potential therapeutic strategies....T cell responses in aplastic anemia
...hematopoietic cells. For this reason, although AAs pathogenesis is obscure, it seems likely that autoimmune responses block hematopoiesis at an early stage but do not entirely eliminate early pluripotent stem cells. Here, Zeng and coworkers provide a first glimpse at some quirks of the immune system in AA patient......rally funded research focuses on understanding the pathogenesis of autism through genetics and neuroimaging. His presentation will review how technology for imaging the structure of the brain has begun to reveal subtle abnormalities. Structural imaging has revealed that the brains in autism are enlarged and tha...Genetic protection against fetal alcohol syndrome?
...k' persons for having a child with FAS. Also, the pathogenesis of FAS could become clearer. This raises the real possibility of treating high-risk, alcohol-abusing pregnant women, thereby reducing the risk of producing a baby with FAS."...Prizes awarded in the 2002 Gottfried Wilhelm Leibniz Programme
...tific field of neuro-degeneration. His work on the pathogenesis of Alzheimers Disease represents an important basis for what have, in the meantime, become realistic therapeutic approaches in the treatment of this illness. In addition, he also belongs to the group of top researchers at international level who are ...Control of fat cell development demonstrated using Sangamo BioSciences' ZFP technology
...the formation of adipose tissue, as well as in the pathogenesis and treatment of diabetes, cardiovascular disease and cancer." The data reported in the paper indicate that this application of Sangamos ZFP technology may improve understanding of these diseases and support the development of potential new treatment...Researchers closer to defining function of two proteins involved in neurotransmitter release
...ch put researchers one step closer to defining the pathogenesis of the disease, were published in Science in July 2000....Predicting preterm birth still nearly impossible, study in New England Journal finds
...ay in understanding the mechanisms involved in the pathogenesis of prematurity, we have a long way to go, Dr. Lockwood writes. In his March of Dimes PERI grant, Dr. Lockwood is following 3,000 women throughout their pregnancies, tracing 26 different clues that have been linked to prematurity. Dr. Lockwood sugges...Findings link disease specific anitbodies to activation of T cells for the first time
...iversity School of Medicine have been studying the pathogenesis of inflammation associated with many conditions, including rheumatoid arthritis, Graves disease, and lupus. This research group has recently identified a number of potential pathways that may be utilized by lymphocyte derived cytokines in driving th...Protein mix-up tied to suppressed immune response early in HIV infection
...has scientific value in terms of understanding HIV pathogenesis in that it provides an excellent explanation of how a positive immune response some people make is actively broadly immunosuppressive." "The findings also provide a target for potential therapies that would interfere with this [TGF-beta] response, w...NIAID unveils bioterrorism research agenda
...anthrax and plague, for example. The mechanism of pathogenesis of Ebola virus and other agents.is also better understood. In addition, rapid progress in determining the genetic blueprints of dangerous pathogens has provided a wealth of information on the underlying biology of those organisms....Scientists reveal secrets of infectious childhood heart disease
... Ph.D., chief of the laboratory of human bacterial pathogenesis at NIAID's Rocky Mountain Laboratories in Hamilton, Mont. Dr. Musser and his colleagues from several institutions determined the genetic blueprint of a GAS strain taken from a patient with rheumatic fever. All GAS bacteria that cause that disease a...