Researchers Discover Ways The Ulcer/Cancer Bug Can Trigger Disease
...others," Gordon says."The challenge is to identify patients who are at risk for developing moreserious disease...xposed to H. pylori strains retrieved fromPeruvian patients with gastritis. The Leb blood group antigen is commonly foundin Peruvians, and most H. pylori strain...Human Metabolite Of Taxol Synthesized In The Laboratory
...etabolism and tissue distribution of paclitaxel in patients is important tomaximising its clinical effectiveness, explains Chemistry Professor DavidKingston, co-author of the discovery. The most efficient way of detecting andquantitating the metabolite is by high performance liquid chromatography (HPLC),but t...Hard Hearts: New Discovery Of Bone In Heart Tissue May Explain Valve Disease
...rstand howcalcium deposits form in the arteries of patients with atherosclerosis and othervascular diseases. A... The team studied 228 valves removed from patients who underwentvalve-replacement surgery from 1994 to 1997 at the Hospital of the University ofPennsyl...Spinal Cord Injury Treatment May Improve With New Findings On Nervous System Damage
...creases long-term disability, deprives spinal cord patients of bowel andbladder control and can account for most symptoms of multiple sclerosis. Cells called oligodendrocytes make white matter white. They manufacture myelin,the fatty sheath that insulates axons like plastic around an electrical wire. If thei...Eviction From Scum Home Makes Disease-Causing Microbe Vulnerable
...: burn victims, peoplewho have had surgery, cancer patients on chemotherapy, orpatients on ventilators or with...the hospital. The bacteria are alsoa big killer of patients with cystic fibrosis: Nearly allchildren with the disease are infected by Pseudomonas, whichmakes pa...Scientists Seek Early Warning Of Drinking Water Threats
...ery young, theelderly, chemotherapy patients, AIDS patients and transplant recipients. In this project, the team will be studying viruses 100 times smaller than crypto- organisms which could more easily pass through some water-treatmenttechnology. Other pathogens can be very resistant to the standard chemical...Retinoic Acid Used In Cancer Treatment
... chemotherapy cocktails given not only to leukemia patients but also to patients with other types of cancer, Yen suggests. "In the meantime," he says, "I think we're addin...Possible Trigger For Heart Failure Identified In Lab Animal Studies
...TNF at levels that are similar tothose observed in patients with heart failure led to dilation of the mainpump...amber of the heart, thus mimicking what happens in patients withheart failure. These investigators also showed that the harmful and noxiouseffects of TNF could...First Evidence That Localized Arthritis Gene Therapy Heals Distant Diseased Joints
...hers have found evidence of gene expression in all patients tested thus far, and no adverse effects have been seen. For additional information about arthritis gene therapy research, please access UPMC Health System's web site at http://www.upmc.edu ....Human Bone Disorder Reproduced In Mice
...y were able to remove cells from the bone marrowof patients with a genetic bone disorder, transplant the cells...ular interest to Drs. Bianco andGehron Robey. MAS patients have regions of bone in which normal marrow has beenreplaced by functionless fibrous tissue that is ...Researchers Discover How Ulcer Bug Becomes Antibiotic-Resistant
...herefore examined pairs of H. pylori isolates from patients in Peru and Lithuania, where infection rates are very high. The two members of each pair came from the same patient and were chosen because one was metronidazole-sensitive while the other was resistant. By analyzing DNA from the H. pylori ch...Evaluation Of The Two Types Of Cardiac Pacemakers Indicates Only Modest Differences In Value
...al chamber pacing was detectable only in a groupof patients with a heart condition known as sinus node dysfunc...re modest than we had expected." In the study, 407 patients aged 65 and older and 60 percent male, were assessedfor health-related quality of life, as measured ...Researchers Discover Existing Drugs May Prevent Enlarged Hearts
...n lead tosudden death. Half of cardiac hypertrophy patients die from thecondition. Olson and his research team showed that cardiac hypertrophy iscontrolled by a single protein, calcineurin, which acts as a gatekeeperto the cells nucleus, the control room where specific moleculesregulate gene function....Antioxidants May Reduce Harmful Complications Of Diabetes
...using damage. "We were able to show that patients with poor control of their diabeteswho were beginn...se rises -- as after a meal. All diabetic patients in the study were taking only drugs referred to assulfonylureas, which increase the sensitivity of r...Renowned Breast Cancer Experts Present Latest Findings At UCSF Cancer Center Symposium
...can provide valuable information that breastcancer patients and their doctors can use to make decisions about ... (CTIP) andAdvocacy Core, will discuss the role of patients in improving treatmentoutcomes. Programs that foster shared decision-making among physicians...Duke Researchers Genetically Engineer Mice To Block Heart Enlargement
...rt. If these drugsfail and the disease progresses, patients can receive a heart transplant as alast resort. "Right now patients with hypertension are treated with several drugsthat block the action of various hormones," said Koc...UPMC Reports On New Liver Assist Device
... device is intended to providetemporary support to patients with acute liver failure until their liverrecovers...e. When human trialsbegin, researchers will place patients with acute liver failure on the device,which is connected to a vein and remains outside their bodies...Aspirin's Preventive Action In Heart Attacks Tied To Genetics
...arch suggests that aspirin may specifically target patients whodisplay an altered gene, called the PlA2 polymo...uple of years, doctors will start to genotypetheir patients to determine if they have polymorphisms. Thisinformation might help with the decision-making process...... recovery. "Successful early reperfusion provides patients with an advantage thatcontinues to increase well b...d to those who did nothave preserved function. Of patients with good ventricular function, 3.1percent died in the first 30 days compared to 12 percent for thos...UCSF Researchers Identify Mutations In Gene Causing Hereditary Form Of Childhood Rickets
...study by examining samples of DNA collectedfrom 20 patients in 18 different families from around the world. T...tionthat can be used for genetic diagnosis. Other patients examined in the UCSFstudy included Poles, Filipinos, African Americans and Caucasians, one Chinesean...