Gene triggers formation of sensory cells in the ear
... system. In the fly, the atonal gene is active in peripheral nerves-those found outside of thebrain and spinal cord. By contrast, the mouse version functions in many areas ofthe spinal cord and in the cerebellum, a region of the brain important incontrolling motion. Surprisingly, mice with a non-working Math1...New targets for nerve diseases, nerve regrowth: It's all in the handshake
... A microscopic study of brain, spinal cord and peripheral nerves in theknock-out mice showed a deterioration...ris gets cleaned up quickly by theimmune system in peripheral nerves. The cleanup is slower in the brain andspinal cord than in the peripheral nerves. "K...Vitamin C levels linked to amount of lead in blood
...idney) disease, anemia, headache, memory loss, and peripheral neuropathy(pain, numbness, or tingling of the arms and legs). In children, signs of acutepoisoning are anemia, abdominal pain and nervous system disorders. At sub-acutelevels of lead poisoning, there are often no symptoms, but such levels can causem...New machine may provide answers about leading cause of blindness
...epeats the process with a flickering light in peripheral vision. By comparing thetwo measurements, researchers can determine how much light is absorbed by the macular pigment and thereforehow much macular pigment a patient has, said Wooten. The whole process takes about 10 minutes. "We know......cessful clinical delivery of a therapeutic genefor peripheral neuropathy could treat this form of nerve damage e...growthfactor may be the solution for patients with peripheral neuropathy in arms andlegs resulting from diabetes or exposure to chemotherapy, for instance. Periph...New research illustrates role of CETP in atherosclerosis
...h can manifest itself as a heart attack, stroke or peripheral vasculardisease, is one of the leading causes of morbidity and mortality in the United States and most of theWestern World. The study described in this article published in Nature Medicine was supported in part by an SBIRGrant from the National Hear...$500,000 gift launches new clinical research effort in peripheral neuropathy
...ity of Chicago to investigate the basic biology of peripheral neuropathy and to search for better treatments a...stigators will concentrate on the basic science of peripheral neuropathy and the other will perform clinical studies involving this disease. It will also suppor...Abgenix initiates phase III clinical trial of graft versus host disease therapy
...es transferring stem cells from the bone marrow or peripheral blood of a healthy donor into an immunosuppressed patient, the host. The transplant is intended to restore normal circulating blood cells and immune cells in patients whose own bone marrow cells and immune system are suppressed by radiation and or ch...Moderate alcohol consumption may reduce your chances of a heart attack
...ociated with coronaryartery, cerebral vascular and peripheral vascular diseases. However, a recent study published in theDecember issue of Alcoholism: Clinical & Experimental Research shows that moderate consumption ofalcohol may decrease production and circulating levels of fibrinogen by up to 20 percent. ...Molecular fats prevent nerve sheath abnormality
...ry of both the central (brain and spinal cord) and peripheral nervous systems. In his laboratory in the UNC Neuroscience Center, Dr. Brian J. Popko, associate professor of biochemistry, studies myelin on two overlapping levels. "We're interested in the basic molecular biology and biochemistry of myelin format...Researchers find new mechanism for growing new blood vessels
...eatment for people with coronary artery disease or peripheral vascular disease. It also links for the first time...us diseases, including coronary artery disease and peripheral vascular disease." Because PR39 is secreted by white blood cells known as macrophages, this newly di...Injured spinal neurons reach out to each other, but not to healthy neighbors
...n neurons and muscle might be re-established after peripheral nerve damage or spinal cord injury, areas for which current treatments are inadequate. The re-coupling of injured spinal neurons by gap junctions is similar to the coupling normally seen among neurons in developing animals. Finding ways to recapitula...Acid-loving microbe may be a key to mine pollution
...s. "It's cytoplasm is surrounded only by a single, peripheral membrane." How the microbe endures the heat, acid and high metal concentrations of its own environment is unknown. But the fact that it does, say Banfield, is certain to be of interest to people studying the origins of life on Earth and the possibili...Time important in transporting critically injured to trauma centers
...hemothorax (blood in the chest) and an injury to a peripheral segment of the liver. Researchers created a model to assess the time of injury in each patient by interviewing the patient and any witnesses or friends, and combine their answers with data obtained from police, sheriff and medical examiner reports. N...Genetic mutations associated with epilepsy
...ders as well." Expressed widely in the central and peripheral nervous system, SCN1A is the genetic code for a sodium channel found in neurons, according to Meisler. Sodium channels are tiny pores that open to allow positively charged sodium ions to enter the nerve cell and then close to cut off the electrical ...New antioxidant vitamin RDAs better, but not good enough
...vent deficiencies such as scurvy for vitamin C, or peripheral neuropathy for vitamin E," said Balz Frei, professor and director of the Linus Pauling Institute at Oregon State University. "But I'd have to say the final report recommendations, although encouraging, don't go far enough," Frei said. "These levels ...Northwestern researchers clone gene responsible for inner ear motor
... at the forefront worldwide in the research of the peripheral auditory system," said David Hanson, M.D., chair of otolaryngology at the Medical School and director of the Center for Sensory and Communication Disorders at Northwestern. "The identification of Prestin is a very important contribution to understand......ack and prevent the diabetes-related complication, peripheral neuropathy, in which nerves are injured. In at least the first three years of the Pittsburgh Center, all of the projects' research and testing will be on laboratory animals. Eventually, investigators expect that findings from these projects will fo...Gene discovery provides link between neurological disorders
...ers in humans. This neurological disorder affects peripheral nerves and leads to progressive weakness and atrop...products that are essential for the maintenance of peripheral nervous system structure and function. Mutations in any of these genes initiate a pathological proc...What happens when genetic information is not correctly edited in brain cells
...an editing enzyme, that is found in brain and many peripheral tissues. They succeeded to impair ADAR2-mediated editing by genetic manipulation in the mouse. Now, the proteins were composed as specified exactly by the nucleotide sequence on the gene. The Heidelberg team show in the Nature study that mice making ...