Muscle protein has role in nerve disorders
...le in muscular dystrophies also may be involved in peripheral neuropathy disorders of the nerves that carry mes...y shed light on the causes and mechanisms of human peripheral neuropathies, which cause pain, numbness and muscle wasting. Peripheral neuropathies can be acquire...Lead poisoning still threatens albatross chicks on Midway Atoll
... recent years, and there have been many reports of peripheral neuropathy, or "droopwing." "Peripheral neuropathy is a classic symptom of very high lead exposure in many species, including humans," says Myra Finkelstein, a Ph.D. candidate in environmental toxicology at U.C. Santa Cruz and lead author of the pape...Lead-based paint is poisoning albatross chicks at Midway Atoll National Wildlife Refuge
...way are so high that the toxic metal damages their peripheral nervous systems, leading to a symptom known as "droopwing"--the chicks are unable to hold their wings tucked up against their bodies, and their wings often drag on the ground. It is a classic symptom of lead poisoning, comparable to the "wrist drop" ...Stem-like cells from peripheral blood restore function in rats with severe stroke
... was collected. These stem-like cells are known as peripheral blood progenitor cells. "This is the first demonstration that G-CSF stimulated peripheral blood cells promote functional recovery after a stroke," said Alison Willing, PhD, assistant profess...Researchers find mechanism that may determine early blood cell fate
...tologists are extracting HSC much more easily from peripheral blood or umbilical cord blood. But since fewer cells are present in these sources, it would be advantageous to expand the cells to increase their numbers, explained Emery Bresnick, UW Medical School professor of pharmacology and senior author on the ...Von Liebig Center awards funding to six projects to commercialize UCSD faculty research
... -- using inner stepbarrier quantum well (IQW) and peripheral coupled waveguide (PCW) technologies. The goal will be to bring them to manufacturable stage, with the vision of developing efficient electro-optic modulation components based upon semiconductor materials and processing technology using the new appro...Can female adult obesity be stopped at birth?
...exogenous administration of NPY causes central and peripheral changes. The central effect consists of a direct suppression of endogenous hypothalamic NPY concentrations and the indirect effect consists of neonatal hyperinsulinemia and/or hyperleptinemia that in turn chronically suppress hypothalamic NPY concent...Stem cell defects are key to Hirschsprung's disease
...velop into the neurons and supporting cells of the peripheral nervous system as well as connective tissues, such as dermis, bone and vascular smooth muscle. NCSCs first show up in the embryo's primitive neural tube, which forms the spinal cord. When everything goes right, neural crest stem cells then migrate t...Tips from the Journals of the American Society for Microbiology
...y the most effective route of vaccination for both peripheral and mucosal immunity," say the researchers. "Intranasal vaccination may be a new approach that could be combined with standard vaccination strategies to give optimal protection both systemically and at mucosal surfaces." (J.M. Lynch, D.E. Briles, D....Researchers identify genes that may be associated with prognosis in pediatric leukemia
...15 years of age. Samples of either bone marrow or peripheral blood were collected and classified at the time of diagnosis. Patients in the study were treated with chemotherapy, and 53 patients entered complete remission, 16 of which were treated with stem cell transplants. In order to identify the genes, in...Critical Therapeutics announces issuance of US patent for novel anti-inflammatory technology
...stimulation therapies that target a -7 subunits on peripheral immune cells," said Walter Newman, Ph.D., CTI's Chief Scientific Officer. "The issuance of this patent enables us to leverage our worldwide exclusive license to develop treatment methods based one or more approaches."......ors found that although the majority of T cells in peripheral blood from patients with CBD are CD28+, a large fraction of the CD4+ T cells that accumulate in the lung are CD28-. Despite the absence of CD28 costimulation, these cells are able to mount an immune response. However, upon comparison with CD28+ cells...UCLA study uses genetic profiling to distinguish types of leprosy
...rium "Mycobacterium leprae," and affects the skin, peripheral nerves, upper respiratory tract and eyes, and can lead to severe disfigurement of the hands, face and feet. It is uncertain how leprosy is spread, and current treatment includes a multi-drug regimen....Stem cells delivered into back of eye hold promise for people with retinitis pigmentosa
...rogressive night blindness and the gradual loss of peripheral vision, and it leads eventually to complete tunnel vision or in some cases total blindness. More than 100 different types of gene mutations have been documented that lead to this degeneration of the retina, and about one in every 3,500 people suffe...Can heart failure impair thinking?
...1-receptors. These characteristics may result from peripheral or central aberrations. The parasympathetic alterations may derive from reduced cardiac muscarinic receptors; however, they also may result from central nervous system (CNS) dysfunction. The cognitive deficits also suggest CNS dysfunction, possibly ...Resistance exercise resets the body clock
...alamus is the central controller and keeps all the peripheral clocks in synch. Exercise can reset circadian rhyt... muscle clock. "Our findings support the idea that peripheral clocks can regulate themselves independently of the clock in the hypothalamus" said Dr. Alex Zambon,......on types of vascular disease --carotid, aortic and peripheral aging is a major risk factor. Recent studies suggest that pathological changes not only predispose the vasculature to disease but also impair compensatory adaptations to various stimuli including shear force and injury. Other studies have demonstrat...Stanford research finds gene variations that alter antidepressant side effects
...ecific receptors found abundantly in the brain and peripheral nervous system. Serotonin has many effects, including mood control, but it also affects the gastrointestinal tract, the sleep-wake cycle and levels of alertness. The researchers looked at one type of serotonin receptor called 5HT2a, thought to be inv...JCI Table of Contents, 1 October, 2003
...rtain transplant recipients. TITLE: IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantation AUTHOR CONTACT: Marcel R. M. van den Brink Memorial Sloan-Kettering Cancer Center, New York, New York, USA. Phone: 212-639-5606 Fax: 917-432-2375 Email: vandenbm@mskcc.or......in those areas that are involved in the control of peripheral organs. This finding suggested that prefrontal cortex neurons could interact with neurons in the hypothalamus that send messages to the spinal cord. The team then used electron microscopy to look at nerve endings in the hypothalamus. They saw that ne...