NSF awards four-year, $3.9 million grant to plant biology team led by University of Georgia
...ated with their function. New leaves grow from the peripheral zone of the SAM, and the central zone replenishes new meristematic cells that are lost during growth. Establishment and maintenance of these structurally and functionally distinct zones of the SAM is achieved by differential expression patterns and i...Retroviral protein triggers proliferation of immune cells
...cells, and in normal human T lymphocytes, known as peripheral blood mononuclear lymphocytes (PBMCs). Jurkat cells are commonly used for immunological studies, while PBMCs contain HTLV-1's normal target cell. Copies of the p12 gene were transferred into both cell types. Then the genes were activated as they wou...U-M scientists find genetic 'fountain of youth' for adult stem cells
...ervous system and neural crest stem cells from the peripheral nervous system. In a previous study, other U-M sci...S) stem cells and neural crest stem cells from the peripheral nervous system (PNS) will be published Oct. 22 in Nature's advance online edition. Co-first authors...JCI Table of Contents, November 3, 2003
...gues isolated dendritic cells prepared from either peripheral blood or bone marrow, which were then pulsed with ...small fraction of VLA-1+ cells present in the CD4+ peripheral blood lymphocyte population significantly reduced the immune response to previously encountered anti...Emory scientists use enzymes to enhance regeneration of damaged peripheral nerves in mice
... to enhance significantly the re-growth of damaged peripheral nerves in mice by treating them with enzymes that... potential for improving functional recovery after peripheral nerve injuries. The Emory scientists were led by Arthur English, PhD, professor of cell biology, wi...Protein biomarkers accurately and quickly diagnose ALS, find Pittsburgh researchers
...ers had neurological diseases (including four with peripheral neuropathies, one with myopathy, one with probable Alzheimer's, one with demyelinating disorder, one with meningitis and one with autoimmune sensory motor axonopathy). CSF was used because it is in close contact with motor neurons and brain cells cal...New understanding of insulin's complexities needed to conquer diabetes
...to understand the molecular links between obesity, peripheral insulin action and the function of insulin-produci...teins-IRS1 and IRS2. IRS1 controls body growth and peripheral insulin action, whereas IRS2 regulates brain growth, body-weight control, glucose homeostasis and fe...Novel approaches to current cellular therapies continue progress toward disease prevention
...and 488 days, there appeared to be a percentage of peripheral blood leukocytes that originated from cloned donor cells, peaking at nine to 17 percent in the granulocytes, and at lower levels in lymphocyte subsets (0.0 to 0.01 percent). Circulating progenitor cells appeared to have an even higher incidence of c...Early treatment can prevent severe vision loss in premature infants
...as retinal ablation, can lead to a partial loss of peripheral or side vision. However, Repka says the benefits of ROP treatments far outweighed any potential risks. "Although there is a slight risk with ROP treatment, the benefits of these treatments are hard to ignore, since they preserve the most important pa...JCI table of contents, January 2, 2004
...mpaired wound healing is analogous to that seen in peripheral tissues but has never before been considered as part of the pathophysiology of ischemic stroke in the context of diabetes. TITLE: Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice AUT......vered a key process leading to the regeneration of peripheral nerves. Nerves in the peripheral nervous system (any part of the body aside from the brain and spinal cord) are capable of regenerati......pace Studies, New York, were used toportray urban, peripheral and non-urban areas across the UnitedStates. In this way, the researchers calculated the extent andlocations of U.S. urban and agricultural land. In addition, observations from the Advanced Very HighResolution Radiometer instrument, aboard the Nation...New study seeks to establish mechanism between areas of the brain and continence
...te the considerable information existing about the peripheral and reflex control of the EAS, there are sparse data about the central control of voluntary contraction of this sphincter in humans. What is known mostly addresses its contraction response to experimental electrical or magnetic stimulation of the mo...Stem-cell therapy could have benefits and risks for heart-attack PTs
...domly assigned to receive an infusion of their own peripheral blood stem-cells and G-CSF. However, an unexpectedly high rate of in-stent restenosis (recurrence of coronary artery narrowing) was seen in patients given G-CSF, either alone or in combination with stem-cell infusion, and therefore trial enrolment wa...Naropin now approved for intrathecal (spinal) administration in the European Union (EU)
... local infiltration anaesthesia, for surgery using peripheral nerve block techniques and for continuous peripheral nerve block for post operative pain relief. The Netherlands acted as the Reference Member State in t...Rimonbant shows promise in addressing multiple risk factors
...nd blocks the CB1 receptors located in central and peripheral areas of the body (such as adipocytes or fat cells), associated with lipid and glucose metabolism, and normalizes the over-activation associated with exaggerated food intake and/or smoking. This action results in weight loss, improvement of cardiova...JCI table of contents, 2 April 2004
...cells, including T cell deletion in the thymus and peripheral tolerance for T cells that escape thymic deletion....el, they administered radiolabeled ligands for the peripheral benzodiazepine receptor (PBR), which is abundantly expressed on brain macrophages, and used PET imag...The APCs of autoimmune disease
...cells, including T cell deletion in the thymus and peripheral tolerance for T cells that escape thymic deletion. These mechanisms, however, fail in some individuals, resulting in an autoimmune response that can be crippling. Many of the factors, both environmental and genetic, involved in autoimmune disease dev...Monitoring macrophages detects dementia
...el, they administered radiolabeled ligands for the peripheral benzodiazepine receptor (PBR), which is abundantly expressed on brain macrophages, and used PET imaging to monitor macrophage infiltration in simian immunodeficiency virusinfected (SIV-infected) macaques. They detected increased ligand binding only i......hways to understanding an array of diseases of the peripheral nervous system, as well as treatments for CMT, the...p a whole new area of exploration for the basis of peripheral neuropathies in general." Several years ago researchers at the Duke Center for Human Genetics led by...