Cancer gene MYC emerging as key research target
... specific organ. Another question is whether this phenomenon of binding without activating may occur with other transcription factors besides MYC. "These kinds of studies and the technology enabling them are so new that many of these questions haven't yet been addressed," McMahon says. Already biotechnology co...Frogs muscle-in on 'wasting' process
...arch also aims to provide further insight into the phenomenon of aestivation in the burrowing frog. Current hypotheses suggest that it produces high levels of antioxidants within the muscle, which inhibit muscle protein breakdown normally associated with disuse. "In aestivation, the frog can lower its metabolic...NASA data shows hurricanes help plants bloom in 'ocean deserts'
...the first documented satellite observation of this phenomenon in the wake of hurricanes," Babin noted. "Because 1998 was the first complete Atlantic hurricane season observed by this instrument, we first noticed this effect in late 1998 after looking at hurricane Bonnie," Babin said. The study found the physica...Scientists learn how adjuvant makes vaccines effective
...pted. The National Jewish team was investigating a phenomenon known as MHC class II signaling, which occurs during interactions between B cells and T cells. When properly stimulated, B cells mature into plasma cells, which release antibodies, one of the immune system's major disease-fighting tools. However, res...A gene that keeps species apart
...ion. At the heart of reproductive isolation is a phenomenon called hybrid incompatibility, in which closely related species are capable of mating but produce inviable or sterile offspring. The classic example of hybrid incompatibility is the male donkeyfemale horse cross, which yields a sterile mule, but man...... research conducted at Brown University. A similar phenomenon has already been observed in worms, according to Brown biology professor Marc Tatar. But never before, Tatar says, has it been seen in fruit flies whose 13,601 genes are shared in many ways by humans. The experiment, detailed in the current issue of...JCI table of contents, 1 June 2004
... the development of multiple antibodies to ECM1, a phenomenon called "epitope spreading," which is frequently seen in other autoimmune skin disorders. TITLE: Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus AUTHOR CONTACT: John A. McGra...The skinny on diagnosing skin disease
... the development of multiple antibodies to ECM1, a phenomenon called "epitope spreading," which is frequently seen in other autoimmune skin disorders....Unexpected changes in Earth's climate observed on the dark side of the moon
...28, 2004 issue of the journal Science examines the phenomenon in an article, "Changes in Earth's Reflectance Ov...lar observations commencing in late 1997. "Using a phenomenon first explained by Leonardo DaVinci," said Goode, "we can precisely measure global climate change an...'Dissecting sleep' by studying the strange phenomenon of cataplexy
...al components of sleep, the scientists studied the phenomenon of cataplexy -- the abrupt loss of muscle tone while maintaining a state of complete wakefulness. The majority of narcoleptics suffer from this malady, in which a strong emotion, even a funny joke, can cause them to drop into a state of paralyzed awa...Cell division can be halted in multiple ways, with implications for cancer
...multiple independent ways to stop cell division, a phenomenon that prevents the spread of genetic mutation, which can make cells cancerous. Results of this research, along with an accompanying editorial, were published in the current issue of the journal Molecular Cell. The findings will be of interest to scien...Genetic barrier to self-pollination identified
...o show the relationship." They took advantage of a phenomenon known as competitive interaction to demonstrate the function of the PiSLF gene in self-incompatibility. It has been known for some time that if pollen has two different S-alleles (which could result when the chromosomal region containing the pollen S...Moderate alcohol consumption increases plasma levels of a protective hormone
...may have on hormones is a logical outgrowth of the phenomenon that women tend to get heart disease later in life than men." For this experiment, 10 middle-aged men and nine postmenopausal women all considered healthy, non-smoking, and moderate drinkers consumed either regular beer or nonalcoholic beer with di...National Academies advisory: May 17-18 meeting on RNA interference
A recently discovered phenomenon known as RNA interference has radically expanded scientists' understanding of the roles RNA plays in regulating the expression of genes. It may eventually be a basis for developing novel therapeutic agents to treat diseases. As part of its Arthur M. ...Artificial light-dark cycles expose circadian clocks at odds with each other
...t makes 33 hours feel like one day. "We think the phenomenon might have a neural base within the brain's circadian clock itself," he said....Wisconsin chemists find a new chink in TB's armor
... or two, many people do not complete treatments, a phenomenon contributing to a worldwide epidemic of multidrug-resistant TB. Adding to the problem, in less developed countries where TB is most common, health care is spotty and drug supplies are frequently inadequate. Kiessling and her colleagues, working with...Staying close to mother helps baby dolphins swim
...aveling through water. He wanted to understand the phenomenon known as 'drafting' whereby dolphin calves position themselves close to their mothers' side in an apparent attempt to reduce the forces required for swimming. His analyses showed that the movement of water around the two dolphins generates two effect...Christopher Walsh wins 2004 Promega Biotechnology Research Award
...vancomycin resistance heightened awareness of this phenomenon long before microbial resistance to antibiotic drugs became an issue of grave concern in health care. Walsh earned his A.B. in biology at Harvard University, Cambridge, Massachusetts, and his Ph.D. in life sciences at the Rockefeller Universi...Biochemist becomes 15th UT Southwestern faculty member serving on National Academy of Sciences
...on the biochemistry of cell death, or apoptosis, a phenomenon in which cells activate a self-destruction program. As the body generates new cells, older cells undergo programmed cell suicide. In the case of cancer cells, they are unable to carry out the self-destruct program, so they grow uncontrollably. Dr. Wa...... Also, we shall strive to incorporate the observed phenomenon that the probability of a synaptic failure is a function both of whether or not a failure occurred at the synapse in question the previous time an afferent spike arrived there, and of how much time has elapsed since a previous arrival. JAY DUNL...