New Discovery About Genes Has Implications For Genetic Therapy
...called exons -- carried useful information. Other pieces of "junk DNA" called introns are interspersed as "spacers" between the exons along the gene. Lambowitz' team found that certain introns could move from place to place along a gene, inserting themselves at specific points along the DNA strand, and ......th this, you can also measure masses of individual pieces of a molecule for further characterization." The researchers -- McLafferty; Gary A. Valaskovic, a postdoctoral associate in McLafferty's lab; and Neil L. Kelleher, a doctoral student -- reported their studies in the journal Science (Aug. 29, 1996). ...Scientists Identify Retrovirus-Like Components In Corn Genome
...istics. However, the genome also contains inactive pieces of DNA and other materials, many of which had not been identified. In the Nov. 1 issue of the journal Science, Purdue biologist Jeffrey Bennetzen reports that the maize genome consists primarily of a class of mobile DNA called retrotransposons. Thoug...New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...versity of Florida Press. "There are two Peruvian pieces in the collection here at the DukeArt Museum," she noted. "There is one that depicts a rat eatingan ear of corn. Then there is one that represents a basket of corn." The first piece is "somewhat problematic," Eubanks said. Thecorn casts it carries h...Gene Shears In Cutting Edge Anti-Aids Trial
...d "gene shears") can be used selectivelyto chop up pieces of genetic material. Gene Shears Pty Ltd went on to provein laboratory experiments that ribozymesit could be used to prevent thereplication of HIV by cutting its genetic material. The chief executive of CSIRO, Dr Malcolm McIntosh, welcomed news tha......troduced them into the bacteria via small circular pieces of DNAcalled plasmids. (Plasmids sometimes carry genes that cause bacteria to becomedrug resistant in the first place). Once inside the bacteria, the synthetic genes produced small strings ofRNAnucleotides called External Guide Sequences (EG...New Description Of Protein May Be Basis For Regulating Cholesterol
... a particular proteinis designed and works and how pieces of its system function, then in principlewe can make designer-engineered proteins with particular properties so as toproduce new antibiotics," he said....New Form Of Gene Therapy Holds Promise For The Future
...luciferase,the researchers inserted specific short pieces of deoxyribonucleic acid (DNA) infront of the luci... The luciferase gene preceded by the three short pieces of DNA wasgenetically inserted into the viral molecule and injected into mice. Researchersthen induc...DNA Enzyme Works In Crystal Form; Yields New Insights Into Gene Copying
...gineered toincorporate only the correct nucleotide pieces into the DNA puzzle. The biochemists also are seeking to understand how the polymeraserecognizes mismatches between the template and the new strand -- like misshapenpieces jammed into a puzzle -- and contorts itself to halt the DNA copyingpr...Hurdle In Ulcer Vaccine Development Cleared
...ode it. Theresearchers then chemically synthesized pieces of DNA with that sequence toserve as a primer in a powerful technique called PCR (the polymerase chainreaction). This allowed them to recover the entire gene from the bacterium. Butinstead of finding one such gene, they found a complex family, which ...Long-Standing Puzzle Of Immune System Is Solved By UCSF Researchers
...ies. Researchers discovered that bits and pieces of immunoglobulin genescan rearrange themselves in myriad permutations to potentially generate 4million different antibody proteins. B cells that produce the antibodiesthat best target invading pathogens are selected for replication. In asense, the...Researchers From Rockefeller University Develop Novel Method To Fight Cancer
... a person's immune systemto choose the appropriate pieces of protein to be presented to the MHC,overcoming t... dendritic cell's natural machineryto decide which pieces of the protein are useful to an individual's immunesystem," says Albert. "We hope that immunotherapy...Biologists Get First Look At DNA-Protein Binding Structure In An Archaeon
...archers formed a single crystal of the proteinwith pieces of DNA from the archaeons Sulfolobus acidocaldarius and S.solfataricus. After freezing the crystal with liquid nitrogen at minus 150degrees Celsius, they were able to determine the three-dimensional structure of the binding complex using X-ray diffr...... “When scientists observed the impacts of the pieces of CometShoemaker-Levy 9 on Jupiter in July 1994, they said that the impact of afragmented comet could never happen here on Earth because the Earth’sgravitational field is too weak to break a comet into pieces,” saidDavid Rowley, University...Change In HIV May Precipitate AIDS
...overcome this limitation by culturing andinfecting pieces of tonsil, which is composed largely of lymphoid tissue,obtained from tonsillectomies. With this advance, they have helped illuminateone of the central questions of HIV pathology--what triggers the eventualdevelopment of AIDS in people who carry HIV?...Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...cells can take up antigens from the tumor, or even pieces of the tumor cells anduse them to train the immune system to attack the tumor." This model suggests treating mice with pre-treated DC's provideslong-term protections against tumor recurrence, as well. In fact, three monthsafter these mice we...Researchers Discover How Ulcer Bug Becomes Antibiotic-Resistant
... already resistant strains -- many bacteria donate pieces of DNA that carry resistance genes to other strains or species. The researchers therefore examined pairs of H. pylori isolates from patients in Peru and Lithuania, where infection rates are very high. The two members of each pair came from the same p...Desert Researcher Receives Environmental Award
...y of Antarctica that he edited are major reference pieces for spacescientists throughout the world. In recent years, he has been actively engagedin cooperation with NASA in the search for life on Mars. He was nominated by Guenther Stotzky, New York University, New York. The American Society for Microbiolog...New Study Shows White Males Have More Receptors For Patent Blood-Vessel Contracting Substance
...ain one aspect of the tangled problem. Using small pieces of left-oversaphenous vein tissue from heart bypass surgeries, they compared the veins ofwhite men and women and discovered a startling difference between them. Theydemonstrated for the first time dramatic differences in the density of receptorsfor a...The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
... dye. But when Karr and Pitnick looked for these pieces after the larvae were allowed to feed for a few hours, they were no longer detectable. Apparently, the larvae excrete the piece with their waste, says Karr, "We were pretty surprised that this segment persisted throughout the development of the embry...