Tag: "pituitary" at biology news

Two enzymes key to calorie-burning, Brown research shows

...rough a complex chemical cascade, to stimulate the pituitary gland and the thyroid. The end result: Food intake is inhibited. The body burns more calories. PC1 and PC2 perform their crucial protein-cutting function not only on the chemical forerunner of TRH, but on several metabolic brain messengers, research...

Leptin and obesity

...tide is produced and released. This stimulates the pituitary gland, which secretes a hormone that relays the message to the thyroid, the master of metabolism. Once activated, the thyroid gland then spreads word to the body's cells to increase energy production. Research results are published in the online earl...

New research shows that the seasons may be involved in onset of menopause

...rch. However, melatonin, a hormone secreted by the pituitary gland, which is generally accepted to play a role in the circadian rhythm (the 24 hour time clock that governs different physiological processes), could be involved. Melatonin binding is found in the ovaries and it also influences ovarian steroid hor...

Evolution's mirror in a fish's spines

...lved in a number of different processes, including pituitary development and craniofacial development," said Kingsley. "So, any changes in the protein itself would affect all of those structures. We think that this finding shows how evolution has been able to make use of exactly the same major developmental re...

JCI table of contents, 15 March 2004

...ion or treatment of bleeding disorders. TITLE: The pituitary adenylate cyclaseactivating polypeptide is a physiological inhibitor of platelet activation AUTHOR CONTACT: Kathleen Freson University of Leuven, Leuven, Belgium. Phone: 32-16-345775 Fax: 32-16-345990 E-mail: kathleen.freson@med.kuleuven.ac.be View...

JCI Table of Contents, January 15 2004

...neuroendocrine system that responds to stress. The pituitary gland serves as a reservoir for the most important regulators of this system: arginine-vasopressin peptide (AVP) and corticotropin-releasing hormone (CRH). AVP is involved in smooth muscle contraction and its effects are mediated through the binding ...

Scripps Research receives $3 million anonymous donation

...s system-- which is responsible for activating the pituitary adrenal stress response and is one of the major neurotransmitters responsible for activating sympathetic and behavioral responses to stressors. The CRF system seems to be central to alcoholism, and preliminary results in preclinical studies at Scrip...

Growth hormone activates gene involved in healing damaged tissue

...ation. Growth hormone, a substance secreted by the pituitary gland in the brain, is responsible for growth in children and young adults, but its levels decline during aging. "The literature had suggested that growth hormone therapy in elderly men stimulates cells to divide," said Costa, leading to increases i...

Researchers find new form of hormone that helps songbirds reproduce

...rigger the release of luteinizing hormone from the pituitary gland and influence gonad growth, something only o...d in the hypothalamus, where it is released to the pituitary gland, which then triggers changes in the reproductive system, Bentley said. But unlike the other fo...

Genetics mutations resulting in delayed puberty are focus of MCG study

...nadotropin releasing hormone, which stimulates the pituitary gland to make follicle stimulating hormone, FSH, and luteinizing hormone, LH. FSH and LH, in turn, prompt the ovaries to produce estrogen and eggs and the testes to produce testosterone and sperm. "When patients present to us with delayed puberty, it...

Research collaboration identifies gene essential to puberty

...ormone (GnRH). In response to this secretion, the pituitary gland releases hormones called gonadotropins, which in turn stimulate the ovaries or testes to start releasing estrogen and testosterone. Individuals with IHH fail to experience normal puberty but can be treated with a variety of therapies, includin...

JCI table of contents, 15 October, 2003

...ci.org/press/17409.pdf HESX1 puts a hex on the pituitary gland The gene HESX1 encodes a developmental repr...lopment in the forebrain and later in the anterior pituitary gland. Mutations within HESX1 are associated with septo-optic dysplasia and mild hypopituitarism. Me...

Old drug works new tricks for iron overload heart disease

...at could prevent damage to the heart, pancreas and pituitary gland from excess iron with a simple pill. This co... heart disease and dysfunction of the pancreas and pituitary gland. Why were these tissues so sensitive to elevated iron levels? We found that for these people, ...

JCI Table of Contents

... hormonal feedback loops between the ovary and the pituitary gland. Ralf Zimmermann and colleagues from Columbi...llicular development by using a model in which the pituitary gland is absent, the prepuberally hypophysectomized mouse. Hypophysectomy prevents advanced follicle...

Can female adult obesity be stopped at birth?

...nthesized and released into the circulation by the pituitary in response to hypothalamic LH-releasing hormone (LHRH) and measured as plasma LH concentrations was altered in response to exogenous NPY. Neonatal exogenous intracerebroventricular NPY administration increased plasma LH concentrations at 21, 60, and...

Researchers discover effective method for killing prostate cancer cells

...n prolactin, a hormone produced by male and female pituitary glands, and how it promotes growth of cells in the prostate led to this new study. Pioneering work by Dr. Nevalainen and colleagues established that prolactin serves as a local growth factor for prostate cells and that Stat5 is the specific signaling...

Premature birth linked to lack of nutrition before pregnancy: study

...ernutrition could impact on the development of the pituitary and adrenal glands of the baby and may well affect the development of other organ systems. So if you're intending to get pregnant, do not diet substantially before the start of pregnancy because it's not necessarily a good thing for your pregnancy an...

Discovery of how prolactin travels to gene's machinery helps explain its role in breast cancer

...they focused solely on the hormone produced by the pituitary gland in the brain. Human trials based on this assumption failed miserably. But in the 1990s, using greatly improved technology and techniques, Dr. Clevenger was able to show that breast tissue itself produces prolactin in significant quantities an...

Researchers find possible link between pre-natal alcohol consumption and diabetes

...xposed rats drank twice as much water, had reduced pituitary content of AVP, a 50 percent reduction in the gene...ompared to the NPE-exposed rats. In addition, the pituitary gland content of the AVP was reduced and the hypothalamus synthesis of AVP was greatly reduced in th...

Pheromones in male perspiration reduce women's tension, alter hormone response

...is reproductive hormone, produced in pulses by the pituitary gland, typically surge right before ovulation but also experience hundreds of smaller peaks throughout the menstrual cycle. Preti and Wysocki found that application of male underarm secretions hastened onset of these smaller pulses. Duration to the...

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