Chemists Develop High-Throughput Method To Synthesize And Screen Novel Antibiotics
...ch can cause severe complications.For example, the plague bacteria contains a heart toxin and thebacteria which causes meningitis contains a neurotoxin. Non-lyticantibiotics may prove to be much safer than currently availabledrugs.......APC inhibitor, avoiding dangerousside effects that plague many anticancer drugs. The APC complex provides "awhole new set of targets which don't function at all in non-dividing cells," says Kirschner. For successful cell division -- when the cytoplasmic and genetic contentsof a cell are faithfully ...Shellfish Toxin Study Provides Possible Clue To Cystic Fibrosis Therapy
...suallylife-threatening, it is a recurrent economic plague on the shellfish industry,particularly in Europe and Japan. The symptoms of cystic fibrosis arise from there being a genetic blockof a major pathway of salt and fluid secretion. The patients' bodies do haveanother pathway of salt and fluid ...Tracking A Killer's Progression
...e discovery a novelattack route used by one of the plague bacterium's killer toxins. Their workwith Yersini...discovered from suchstudies in the past. Moreover, plague still poses a public health threat and continues to be a globalproblem. If a drug-resistant strain ...Could A Nasal Vaccine Finally Get Rid Of The Black Death?
... worldwide pandemic started byantibiotic-resistant plague bacteria. Round the world, one to two thousand cases of the plague are reportedeach year. Bubonic plague is caused by the bacterium Yersinia pestis, which isspread by ...Slimy Bacteria Common Cause Of Chronic Infections
... is the culprit behind many nagginginfections that plague children and adults, say scientists from Montana StateUniversity-Bozeman and the University of Iowa in a paper that will be publishedMay 21, 1999 in the journal Science. Ear infections, periodontitis and cystic fibrosis pneumonia are just ...New electrical transformers will improve power quality
...mers that will smooth out the uneven voltages that plague today's grid and prematurely age electrical hardware ranging from light bulbs to motors to power supplies in electronic equipment. They are designed with so-called "solid state" technology, meaning they rely primarily on semiconductor components such...Bubonic plague kills by cutting off cellular communication
Bubonic plague kills by cutting offcellular communication, say U-M scientists. One molecule holds the key to plague's lethal effects. ANN ARBOR --- Yersinia pestis, the deadly bacterium that causes bubonic plague,kills by cutting off a cell's ability to communic...Seeing one weapon from a food-borne pathogen
...rotein that allows a close relative of the bubonic plague bacteria to infectintestinal cells and cause food poisoning. When the bacterium Yersinia pseudotuberculosis is consumed incontaminated food, it gains access to certain cells in the intestinal epitheliumcalled M cells. Once inside the intestines, ...Human plague cases increasing in Southwest
...te in Sevilleta, New Mexico, have found that human plague cases in New Mexico occurred more frequently after...normal, a 60% rise in the number of cases of human plague resulted. The scientists report these results in a paper published in the November issue of the Ame...Wake Forest starts center for human genomics
...isk of developing many of the common diseases that plague human society, including heart disease, stroke, diabetes and multiple forms of cancer, are intimately linked to the interaction of genetic factors and environmental exposures including lifestyle factors such as diet, physical activity and behavior," ...Formosan termite may be top concern of entomologists of the new millenium, according to report
...tten worse, if anything. Fleas carried the bubonic plague across Europe, and millions died. Mosquitoes have ..." said Hunter. "Malaria, leishmaniasis, dengue and plague have come back, in some cases where they were thought to be under effective control." Public health ......ecting the world's richestcountries. Diseases that plague poor countries, such as malaria and sleepingsickness, have been largely ignored, said Dr. Richard Feachem, PhD, DSc(Med),founding director of the Institute for Global Health, and a professor ofinternational health at UCSF and UC Berkeley. "Modern bio...International trade imperils U.S. plants, animals and crops
...geland for grazing cattle, while fungi and insects plague both croplands and forest trees. A recent arrival is the Asian long-horned beetle, first detected only in the past three years, now feasting on hardwood trees in the Northeast. "This beetle came over from China in wood packaging material and is des...Biological warfare: an emerging threat in the 21st century
...s - including the bacteria that cause anthrax, the plague and typhoid. Any scientist bent on destruction co...ng them to experimental doses of anthrax, cholera, plague and other pathogens. Evidence also exists of a deliberate tularemia - or rabbit fever - attack by So...Biosecurity net closes on marine invasions
...of a North Pacific seastar (Asterias amurensis) in plague proportions in the Derwent Estuary, Tasmania. In just a decade, the seastar has become a dominant species in two southern Australian marine ecosystems, the island State of Tasmania and then leap-frogging Bass Strait to reach Port Phillip Bay and Melb...Baboon studies suggest strategies for coping with stress
... Because baboons are rarely threatened by famine, plague or predators, they are good models for socialized disease, Sapolsky says: "Baboon societies are ironically a lot like Westernized humans. We're ecologically privileged enough that we can invent social and psychological stress. Baboons in the Serenget...Scientists track down the root of cloning problems
...nological advances, two major problems continue to plague the field of animal cloning: few clones survive to term and those that do are grotesquely large. The root of these problems has remained a mystery until now. But a new study led by the Whitehead Institute traces their origin to two separate ...AIDS in Africa has potential to affect human evolution, UC Berkeley scientists report
...portions over the course of history - from bubonic plague and measles to smallpox - have affected human evolution, selecting for genes that reduce mortality before or through the reproductive years. Evidence, however, is hard to find, Slatkin said. That was why he and postdoctoral fellows Paul Schliekelman...Genetic mutation influences spread of AIDS; African population lacks mutation
...se of widespread epidemics of smallpox and bubonic plague during the Middle Ages. Several studies have suggested that plague and smallpox use the same CCR5 receptor to infect cells. "Our model suggests that the CCR5 mutation ...