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Jefferson Researchers Use Gene Therapy To Treat Rare, Inherited Brain Disease

...hase 1 clinical trial. To date, the Jefferson team plans to treat four Canavan disease children. The therapy will consist of a ventricular catheter implanted under the scalp, allowing access to the brain's ventricles and cerebrospinal fluid, and to allow possible additional treatment. The Jefferson researc...

Computer Models Find Cost-Effective Solutions For Species Preservation

...vation researchers to studythe most cost-effective plans for species preservation. In a paper to be published in Science Friday, March 27,University of Cincinnati researcher Jeffrey Camm and hiscollaborators will report on the use of optimization techniquesto select the right tracts of lands for nature res...

Yale Announces New Biotech Firm

...ative Research (OCR). MSI, which initially plans to hire 20-30 people and to occupy10,000 square feet of laboratory space, is the fourth biotechnologycompany based on Yale research discoveries to be launched this year,Gardiner said. He added that he hopes to maintain a pace of launchingthree or fo...

Targeted Genetics, M.D. Anderson Cancer Center And University Of Pittsburgh Report Phase I Clinical Trial Results Of Gene Therapy Treatment For Cancer

...table disease after E1A therapy. Targeted Genetics plans to initiate Phase II clinical trials for the treatmentof head and neck cancer in the second half of 1998. "This is extremely exciting for Targeted Genetics because the work presented atAACR validates our E1A approach to gene therapy," said H. Stewart...

How Did Life Begin? Biochemical Evolution On Chemical Surfaces

...s into the first primitive proteins. Smith plans a trip to Australia, where some of the oldest andleast-metamorphosed rocks and minerals are found, to look for more naturallyoccurring organophilic zeolites like the mutinaite found in Antarctica. He'shoping these minerals still contain evidence of ...

NIGMS Makes First Awards For

...petition between cell division and cell death. He plans to study fruitflies--which utilize many of the same genetic pathways as humans--to identifygenes that maintain the balance between cell division and cell death. The workpromises to provide a basic understanding not only of growing tissue, but alsoof...

EPA Should Redirect Some Research on Toxic Airborne Particles

...reas not meeting thestandards will have to develop plans to control particulates. EPA estimates that compli...s for AirborneParticulate Matter , examines EPA's plans for research and identifies the10 most critical needs for strengthening the scientific data. The re...

New RNA Repair May Lead To More Successful Gene Therapy

...s quite promising." Like sending imperfect plans to a factory, errors in messenger RNAproduction result in defective or inadequate protein production, he said. Insevere cases of untreated beta thalassemia, those errors lead to acute anemiaand death at a young age. "The advantage of our nove...

3,500 Earth And Space Scientists To Report Latest Findings At Boston Meeting

...ynes Convention Center.The program will also cover plans for the 2001 Mars rover mission, which willsample rocks for evidence of wet conditions and signs of ancient life. Attendeeswill have an opportunity to put questions to scientists who are leading theinvestigations. Another special event is the fi...

Perkin-Elmer, Dr. J. Craig Venter, And TIGR Announce Formation Of New Genomics Company

...hase of the entire human genome." The new company plans to make sequencing data publicly available to ensurethat as many researchers as possible are examining it and that applications,such as the development of diagnostic tests and new drug discovery, areas broad as possible. Commenting on the proposed n...

Biggest Acoustics Meeting Ever

...ments to develop more sophisticated fishmanagement plans than previously possible. The Acoustics of Opera...sity of Bonvicini in Italy and others will discuss plans to reconstructthe famous La Fenice opera house in Venice after it was destroyed in a fire. Carmine I...

Fetal Lead Exposure May Reduce Immunity

...h embryonic chickens as animal models, but have no plans to extend the studies at the university to humans. But humans subjects, they say, would not be hard to find. "Unfortunately, pregnant women even in this country are exposed to these levels of lead through drinking water, old paint and other source...

Cell Pathways Reports Extension Study Results Showing Ability Of FGN-1 To Prevent Formation Of Precancerous Colon Polyps

...ting normal cells. Cell Pathways Inc. has begun or plans to initiate clinical trials of FGN-1 in1998 in sev...reast cancer recurrence in February 1998. CPI also plans to begin twoadditional Phase II trials in precancerous indications in 1998. Cell Pathways, Inc. is a...

Major Risk Factor For Cervical Cancer Found

...actor for cervical cancer." The research team now plans to do further, larger, studies in differentpopulations to confirm and extend their findings. "In the future testing for p53 status may prove to be another useful tool inassessing a woman's risk for developing cervical cancer," commented Dr Storey. T...

Researchers Identify Function Of Brain Receptor Subunit Linked To Memory, Stroke, Dementia

...swhether neuronal activity is worthy of memory. He plans to further study therole of NMDA receptors in synaptic plasticity and memory formation....

Carnegie Mellon Researchers Develop Nation's First Robotic Tour Guide For The Dinosaur Hall At Pittsburgh's Carnegie Museum Of Natural History

...e-scenes activities at the museum. RedZone plans to continue technology development of 'Sage' throu...t will debut at the museum inthe fall. The company plans to advance the navigation system and develop thefirst pieces of interactive capabilities. "...

Does Mountain Living Slow Rate Of Molecular Evolution?

... can manifest themselves in altered body plans or behaviors. But what initially sparks those changes at the genetic level is largely unknown. The evidence that life at higher eleva...

Gene May Hold Key To Treating Life-Threatening Cholesterol

... have found a perfect drug target in LXR-alpha. He plans to look for ways to biochemically design hormonal ligands that can speed metabolism and reduce dietary cholesterol levels in humans. Screening for mutations in LXR-alpha also may help identify inherited defects in cholesterol metabolism. "This study ...

Computers, GIS Help Prevent Ground Water Contamination

...izer applications. Other states are modeling their plans after Indiana's, Engel said. "[Engel's research] is certain to be one of the central agricultural engineering achievements of the 21st century. It offers the prospect for highly cost-effective use of resources and the virtual elimination of nonpo...

Ground-Breaking DNA Research Leads SFU Grad To The Top

...NA enzymes. After finishing the Yalefellowship, he plans to return to Canada, preferably to set up his own lab at auniversity. "I love Canada dearly and I really want to come back if there is ajob for me," he says. As for the SFU gold medal, Li says he's humbled by the honor. "I thinkof myself as a...

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