Tag: "plaque" at biology news

American Heart Association Announces Top 10 Research Advances For 1998 -- Gene Therapy Among The List

...therapy to create a "natural" bypass to circumvent plaque obstructions in the heart's blood vessels In the ... showing that the area of the blood vessel where a plaque obstruction develops can become inflamed and that the inflammation can actually weaken the surface o...

UB Researchers Identify Specific Oral Bacteria Most Likely To Increase Risk Of Heart Disease

...asethe risk of heart attack by: 1) contributing to plaque formation, which narrowsblood vessels and increases the chance of clots forming, 2) accumulating arounddamaged tissue, such as a lesion in the blood vessel or a replaced heart valve,which also can narrow blood vessels and cause clots, and 3) inducing...

Chinese Condiment Cuts Blood Cholesterol

...ol because it collects in theblood vessels to form plaque that can block blood flow, triggering a heartattack or stroke. Individuals who did not receive the supplement had reductionsof total blood cholesterol and LDL of about 7 percent, says Chang. James Rippe, M.D., associate professor of medicine at Tuft...

Study Furthers Understanding Of Critical Alzheimer's Disease Gene

...ormed. This continuing study of the mechanisms of plaque formation,researchers believe, moves them ever closer to the possible development of novel drugs to intervene in the processes leading up to Alzheimer's dementia. Naturally occurring mutations in PS-1 are found in about 40 percent of peoplewith FA...

Molecular Effect Of Vitamin E On Plaque Formation Identified

... 5-lipoxygenase, which is key to the initiation of plaque formation. "Mounting evidence suggests that plaque formation is an inflammatory process,"Devaraj said. This enzyme, 5-lipozygenase, produces a substanc...

Stress Increases Blood Chemical Related To Heart Disease

...toney said. This contributesto the development of plaque on the walls of the arteries. The study compared pre- and post-menopausal women because there are differencesbetween the two groups in both risk for cardiovascular disease and in physicalresponses to stress. The results did show one difference in po...

Gladstone/UCSF team discovers interaction of two brain proteins may be key factor in development of Alzheimer's disease

...gh levels of A-beta can be neurotoxic even without plaque formation.Mucke noted, "These results could provid... explanation for thediscrepancies observed between plaque load and functional deficits in peoplewith AD." In this earlier study, Mucke and his collaborators u...

NIEHS-cloned gene linked to a natural substance that reduces vascular inflammation, a key to arterial clogging

...on." Atherosclerosis, a thickening and build-up of plaque in thearteries, occurs when the innermost layer of the artery, the endothelium,becomes damaged by cholesterol, toxins, oxidants, or infectious agents. The damaged endothelial cells in the artery walls produce adhesionmolecules. These adhesio...

Scientists suggest genetic shutdown links estrogen, heart disease

...rectomy, a "roto-rooter"- like process that clears plaque fromcoronary arteries. They used specialized molecular probes to identify "normal"ER genes and those that were methylated. "Many studies show women on hormone replacement therapy are at decreasedrisk for heart disease," says Post. "Our re...

AGU names new journalism award for David Perlman

...n any medium except books. The awards consist of a plaque and $2,000, presented at AGU's Spring or Fall Meeting. The 1999 winner of the Sullivan Award was David Sington for his television series, Earth Story, produced by the BBC and The Learning Channel. Sington was the first broadcaster and first person f...

Abgenix reports positive clinical data with ABX-IL8 in Psoriasis

...ea (BSA), Physician's Global Assessment (PGA), and plaque photographs. The company also indicated that it pl...improvement of >25%). BSA and PGA measures and plaque photographs also showed dose dependent improvement. "The Phase I/II trial of ABX-IL8 was primaril...

Call for nominations: ASM public communications award

...dcast media. The recipient will receive $2,500, a plaque and travel expenses to the 2000 ASM General Meeting (May 21-25 in Los Angeles) for presentation of the award. Stories (both individual and in a series) concerning the microbiological sciences appearing in print or broadcast media available to the ge...

UF dental researcher develops genetically altered bacteria strain that may fight cavities for a lifetime

...dental hygiene will always be necessary because of plaque buildup," Hillman said. A National Health Spending Trends report indicates that $48 billion was spent on dental services in 1996. Hillman says the future treatment would result in dramatic savings for patients. For the past 20 years, the Natio...

University of Colorado salmon study spawns new insight into human brain aging

...cally stained to identify areas of APP and amyloid plaque build-up. Salmon are a good model to study because the physiological cascade of aging effects proceeds much like that in humans, although salmon run an astonishingly swift course toward death following reproduction, said Norris. Both salmon and hu...

Evidence suggests food preservatives may help prevent cavities

... benzoate prevent the bacteria from acidifying the plaque and causing cavities. The bacteria are still there -- you have to take a tooth brush to get rid of them -- but they're not causing damage." In his laboratory, Marquis has also shown that the common medicine ibuprofen, a non-steroidal anti-in...

UC Irvine molecular biologists discover key protein interaction that stabilizes cholesterol levels in cells

...g there, which can lead to the buildup of arterial plaque and to potential heart attacks and strokes." By using the CHIPS observational technique, Osborne and Bennett studied a group of proteins, called sterol regulatory element binding proteins, that regulate cholesterol and fatty acid levels in cells. ...

Research changes surface mine reclamation practices, policy

...international level. The $500 student award and plaque are given annually to an M.S. degree student having a curriculum in a scientific discipline directly related to and leading toward a profession in disturbed land reclamation and restoration. The award is meant to provide an incentive to follow a prof...

African Americans fare less well than whites after stroke prevention surgery

...s perform more than 130,000 CEAs annually to clear plaque from the inner lining of the carotid artery, one of the main arteries supplying blood to the brain. Blocked carotid arteries are one of the most common causes of stroke. "Previous studies have shown that CEA is performed less frequently in African ...

Hopkins scientists show enzyme is key to hallmark of Alzheimer's

...esponsible for forming the molecules that comprise plaque within the brain's nerve cells. Beta amyloid - the plaque molecule - forms inside nerve cells, then is shuttled outside where it collects into plaques. Beta-...

Researchers reveal insidious role of a 'serpin' in Alzheimer's Disease

...mulation of Alzheimer's disease-associated amyloid plaque in the brains of mice, suggesting a possible new t...ow demonstrates that ACT insidiously increases the plaque burden in the aging brain." The researchers report their findings in the December issue of American ...

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