Tag: "plaque" at biology news
Results from open-label Raptiva study suggest continued benefit with long-term treatment
...for the continuous treatment of moderate-to-severe plaque
psoriasis. In clinical trials, Raptiva was admini...or Raptiva for the treatment of moderate-to-severe plaque
psoriasis in patients 18 years or older. The BLA submission included data from over 2,100 patients ...
Phase III study results with Raptiva in the treatment of psoriasis presented at Annual AAD meeting
...in the treatment of adults with moderate-to-severe plaque
psoriasis. The study results were presented by Ke...for the continuous treatment of moderate-to-severe plaque
psoriasis. In clinical trials, Raptiva was administered via subcutaneous injection and in several o...
Prions offer nanotech building tool
...yloid". In humans, amyloids are best known as the plaque
that gunks up neurons in people with Alzheimer's, mad cow disease and other neurodegenerative illnesses. This may be one reason why these diseases are so resistant to treatment. However, yeast prions used as the source of protein in these experimen...
Researchers find protein mechanism for potential atherosclerosis development
...ating and taking up more cholesterol, resulting in plaque
formation. Continued expansion of this plaque
leads to arterial obstruction, which often results in heart attack or stroke. We wanted to find out ...
Gene variation in immune system cells lowers heart disease risk
...blood vessels, thereby triggering inflammation and plaque
formation that eventually blocks the vessel. Working with colleagues at the National Heart, Lung, and Blood Institute (NHLBI), the NIAID scientists performed a detailed genetic analysis of the offspring cohort of the famous Framingham Heart Study. ...
Argonne research offers clues to Alzheimer's plaques
...Previous research in the field had shown that each plaque
is a tangle of millions of ribbon-like peptide chains called -amyloid fibrils. Peptides are chains of amino acids, simple organic compounds that form the building blocks of proteins. Inside the body's cells, amino acids are used for growth, maintena...
Molecule helps prevent inflammation and heart disease in fat-fed mice
...ds of people die every year from a sudden ruptured plaque
without having experienced any previous symptoms. ...rts. For example, they had 3.3 times the amount of plaque
buildup clogging the thoracic aorta (the artery that extends from the heart down into the diaphragm)...
Automated imaging of brain tissue, high-quality glimpses inside arteries
...rovide a detailed map or mechanical profile of the plaque
that causes the blockage. The new system, incorpo...er CMBB3, Intravascular imaging of atherosclerotic plaque
with optical coherence tomography, Monday, June 2, 4:15 PM) ULTRAFAST LASER AUTOMATES MICROSCOPIC-S...
Scientists find genetic link between blood flow patterns and cardiovascular disease
...iagnostic tests or gene-based therapies to prevent plaque
ENBREL provided rapid and significant relief for psoriasis patients in second pivotal study
...etanercept) in the treatment of moderate to severe plaque
psoriasis experienced significant and rapid improv...tates, one million of whom have moderate to severe plaque
psoriasis. ENBREL is not approved by the U.S. Food and Drug Administration for the treatment of pso...
New theory of cell death proposed in UCSB Alzheimers research
...nt autopsy that revealed the now familiar neuritic plaque
and neurofibrillary tangles that mark the disease....
Tipping the balance of prion infectivity
... toxic proteins that aggregate into brain-clogging plaque
to fold into less toxic versions, they said. The researchers, which included Howard Hughes Medical Institute (HHMI) investigator Jonathan Weissman , Peter Chien, HHMI predoctoral fellow Angela DePace and Sean Collins at the University of California...
Francis Collins and Ari Patrinos receive Energy Secretary's Gold Award for Human Genome Project
...Department's highest honorary award and includes a plaque
with citation, a medallion and a rosette. Secretary Abraham presented Drs. Collins and Patrinos with the award in a ceremony at DOE headquarters. Director of the National Institutes of Health Elias Zerhouni represented the Department of Health and H...
New research technique provides unique glimpse into Alzheimer's disease
...e apparently is a shift during aging and/or during plaque
development that affects how ABeta is moved between the two compartments." Because microdialysis is performed in living animals, the team was able to take multiple interstitial fluid samples from each animal over the course of several hours. This pro...
FDA approves Raptiva (efalizumab) for chronic moderate-to-severe plaque psoriasis
...A) for the treatment of chronic moderate-to-severe plaque
psoriasis in adults age 18 or older who are candid...e continuous control of chronic moderate-to-severe plaque
psoriasis and can be self-administered by patients as a single, once-weekly, subcutaneous injection....
Scripps scientists link ozone to atherosclerosis
...erosclerotic plaques. DeLaria provided a sample of plaque
material from a patient who recently underwent an ..., and their colleagues studied the atherosclerotic plaque
samples, they found the evidence they were looking for. The atheronals--signature products that were...
Researchers describe novel gene mutations associated with Alzheimer disease
...senilin is a protein that has been associated with plaque
formation. Sandro Sorbi, M.D., of the University of Florence, Italy and colleagues obtained DNA samples from 45 individuals with FAD. Participants were outpatients from the neurology departments at the Universities of Florence and Parma, and the San...
Dec. 17 JAMA study shows new 'biologic' drug reduces psoriasis symptoms, improves quality of life
...ult, the skin piles up and forms red, scaly, thick plaque
lesions. For the study, patients completed a questionnaire asking how psoriasis affects their daily life, work and their relationships. They also reported symptoms, including pain, itching, bleeding, burning and scaling. "Biologics are injected, ins...
John Allen Paulos receives prestigious AAAS Award for Public Understanding of S&T
...ence." A monetary prize of $5,000, a commemorative plaque
and other honors are bestowed upon winners of the AAAS award. For more background on the award, please see http://www.aaas.org/about/awards/...
Mouth microbes may help shape immune system, says Stanford research team
... which involves directly analyzing the microbes in plaque
surrounding the tooth rather than growing the micr...icrobial world. By preparing DNA directly from the plaque
and studying each bacterial genetic sequence, they have found microbes never before located in the m...
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