Testosterone dose-repsonse relationships in healthy young men
...ns, secondary sex characteristics, erythropoiesis, plasma lipids, and bone metabolism. However, testosteron...in muscle mass and strength might adversely affect plasma lipids, hemoglobin levels, and the prostate. The Study The primary objective of this study was to d...Women more susceptible to orthostatic hypotension
... exist in sympathetic reactivity. Reports of lower plasma norepinephrine concentrations in women during orth...mpathetic outflow may also be diminished. However, plasma norepinephrine concentrations are not a precise indicator of sympathetic outflow, and more direct me...Monitoring epithelial plasticity, one cell at a time
The kidneys maintain plasma volume and composition by adapting to shifts in th... basolateral surfaces, these two cell types affect plasma pH in opposing directions: b cells secrete HCO3? toward the lumen, acidifying the plasma, whereas a ...The anti-inflammatory effect of apoptotic bodies
... is usually restricted to the inner leaflet of the plasma membrane but that accumulates on the cell surface during apoptosis. Exogenous apoptotic cells introduced into inflamed lung tissue in vivo are taken up by local macrophages, which then release active TGF-b1 and suppress the effects of inflammatory cy...Growth hormone may boost production of disease-fighting cells in elderly
...ent of men have dramatically low concentrations of plasma insulin-like growth hormone-1 (IGF-I), falling to levels found in growth-hormone deficient children, said Keith W. Kelley, lead investigator and professor of animal sciences in the UI Laboratory of Immunophysiology. This is known as the somatopause ...The body's production of melatonin may be the reason why the elderly can't get a good night's sleep
...p timing, the rhythms of core body temperature and plasma cortisol are also known to occur at an earlier hou...e. However, previous studies reveal that nocturnal plasma melatonin concentrations in most very healthy older subjects are not significantly reduced compared ...'Night eating syndrome' may be related to the performance of the body -- not the mind
... a cycle of about 24 hours) by a nocturnal rise of plasma concentrations of melatonin and leptin and an incr...renocorticotropic hormone) and cortisol levels in plasma were measured. The subjects stayed in bed during the observation period. Blood was collected in pre...MCG researcher develops animal model for studying autoimmune disease
...tic cells found throughout most solid body tissue, plasma cytoid dendritic cells thought to be involved in c...mph nodes and spleen. He's most interested in the plasma cytoid and lymphoid tissue types not only because of their role in natural immunity, but because the...Preliminary research suggests potential nitric oxide link to cocoa consumption
...ut not the low-flavanol version, displayed a renal plasma flow response that was consistent with the hypothesis that the nitric oxide pathway may play a role. Research is currently underway that will conclusively determine whether or not modulation of nitric oxide synthesis is the responsible mechanism for...Dartmouth biologists say algae might be missing mercury link in aquatic food chain
...into the Daphnia. They used an inductively coupled plasma mass spectrometer, or ICP-MS. Dartmouth owns one of the few ICP-MS in the northeast, and Pickhardt and his team have developed new methods to measure the mercury at lower levels than ever before. "These results tell us that over the season in a lake...Other highlights in the March 20 issue of JNCI
...al cancer directly or indirectly by increasing the plasma level of insulin-like growth factor-I (IGF-I). Pla...he A allele rather than the T allele. The ratio of plasma IFG-I to IFG-I binding protein-3 reflects the amount of available IGF-I, and a lower ratio was found...Unexpected links found between many RNA viruses
...These capsids are formed in a structure called the plasma membrane, where retroviral replication takes place. This replication machinery is triggered by an RNA packaging signal that parallels the action of the signal in BMV. These same principles of sequestering a viral RNA intermediate and its polymerase, ...Forging a link between brain and bone
...possibly mediated by changes in corticosteroids or plasma calcium levels. However, Baldock et al. find no evidence for such a mechanism, and they suggest instead that rapid bone deposition and high trabecular bone volume result from direct neural control of bone growth. The absence of Y2, either specificall...New post-genomic technique chronicles protein life cycles
...ewly synthesized connexins were transported to the plasma membrane in small, 100 to 150 nanometer vesicles and incorporated at the periphery of pre-existing gap junction plaques. Older connexins were instead removed from the center of the plaque and transported into degradative vesicles of various sizes. ...Eliminating battlefield transfusions
...oblematic. In the future, however, a unique blood plasma volume expander may reduce or eliminate the need f...S military overseas. Four studies involving blood plasma volume expanders performed in animals is the subject of a presentation by Paul E. Segall, Ph.D., Hal...New findings could lead to innovative treatment technologies for patients with sickle cell
...on of 0.5 U/ml, which corresponds to the levels in plasma during clinical therapy, reduced the adhesion of sickle erythrocytes to immobilized P-selectin. Conclusions The findings from this research demonstrate that sickle red cells traveling through the blood stream may adhere to a protein called P-selectin...... speed in a desk top centrifuge, and the resulting plasma was stored at -80oC. Humoral factors indicative o...e development of diabetes were determined in these plasma samples. Plasma glucose levels were measured for control and diabetic rats; plasma non-esterified f...