Tumor Suppressor Gene Located In Liver Cancer Cells
... -- A malfunctioning "traffic cop" gene apparently plays an important role in the formation of liver cancer... M6P/IGF2r by investigating whether this gene also plays a role in the formation of other types of tumors. After four years of study, Jirtle said, "We are a...Second Breast Cancer Gene Located
... The researchers do not yet know whether BRCA2 plays a role in the developmentof sporadic, or non-inherited, breast cancers. "Although important in increasing our understanding of breast cancer,there are still crucial parts of the jigsaw left to piece together,"said Gordon McVie, scientific di...Race Plus Roaches: A Breathtaking Link
...searchers say. "We honestly don't know why race plays a role independent of poverty," says Peyton Eggleston, M.D., professor of pediatrics and co-author of the study. Eggleston speculates that racially based genetic differences, important in the regulation of immune responses, hold a clue. Low socioecon...Florida Researchers Discover Gene For Fatal Childhood Disease
...n cells. Scientists also believe this gene plays a role in regulating thespread and development of cancers in general, and in protecting againstcertain autoimmune disorders. "This is significant for several reasons. Nobody knew what caused thisfatal disease," Kingsmore said. "Now we can design a...Newly Discovered Gene Halts Cell Division and May Have Cancer Link
... Dr. Benezra says. The MAD2 checkpoint appears to plays an essential role in the cell cycle, Dr. Benezra says. After a cell's DNA is copied, each pair of the duplicated chromosomes is bound together at structures, called centromeres, that fit around each chromosome like a napkin ring. In order for a cell ...NCAR Scientists Trek To Africa For Biosphere-Atmosphere Chemistry Study
...oprene, a fast-reacting chemical emitted by trees, plays an important role in the atmosphere's overall chemical balance. "Measuring isoprene is a key to this experiment," says Klinger. On hand for the field work will be five NCAR scientists and technicians, along with four scientists from the University of...Study Examines How Mechanisms Evolve To Regulate Bee Development
...wn division of labor among worker honey bees,which plays a key role in the ecological success of the species. This project, however, looked specifically at how juvenile hormone affectsthe behavior of the stockier, bigger-winged drones in an attempt to gaininsight into the evolution of the mechanisms invol...Medicinal Leech May Offer Clues To Neural Regeneration
...micals reactions. Studies show that the NOS enzyme plays a role in a number of functions, such as learning ...operates at a cellular level. "We suspect that NOS plays an important role in the organization of many events, but we have not yet determined how it sends it...Bottom-up Ecological Processes Better For Clear Waters, Study Finds
...of the web. The way energy moves through food webs plays a keyrole in determining fisheries production in lakes and oceans. In most lakes around the world, the most common pollutants causing murkywater are actually nutrients that fuel the growth and number of tiny plantsat the bottom of the food chain. Li...ORNL Finds Common Genetic Cause For Epilepsy, Migraine
...ork among nervous system cells. "Calcium flow also plays a critical role in the growth and internalregulation of nerve cells." Further research into the structure and function of the gene will improvediagnosis and may aid in development of new treatments for migraine. In addition to the role of genes sugge...Scientists Determine 3-D Crystal Structure Of Cancer-Causing Protein
... mutated form of acellular protein. The Src family plays an important role in regulating thebody's immune s...ults of thisstudied confirmed the finding that SH3 plays an important role in theactivation of Hck. "We know that Nef binds tightly to the SH3 domain of Hck,...Molecular Imposter Rebuts Long
...ated that hydrogenbonding between DNA's four bases plays a key role in the amazingaccuracy of this genetic blueprint. But new researchwith a molecular imposter is calling some of these long-heldbeliefs into question. Results presented in the February 12issue of the Journal of the American Chemical Society...Team Identifies Switch For Tumor Suppressor Gene
...a first steptoward better control over a gene that plays a role in many casesof human cancer. The research by a team from the University of RochesterCancer Center is on the retinoblastoma (RB) gene, one of thefirst known in a class of genes known as tumor suppressors, whosejob it is to rein in cell gr...Low Iron Levels Cause Weakness In Women Who Are Not Anemic
...essential component of hemoglobin in the blood and plays an important role in oxygen transport and utilization. When people consume iron-deficient diets, they first deplete their iron stores in the liver; at the final stage, they become anemic due to insufficient iron to produce new red blood cells. Haas...Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos
...2/p130 and showed that it makes a protein that plays a vital role in controlling cell cycle in all human and mammalian cells. When pRb-2/p130 is altered and cannot produce its protein, the cell may not reach its natural stage of programmed cell death. Instead, the cell continues to live a...Resistance To Leptin Contributes To Obesity
...nergy use. "These data confirm that leptin plays an important role in thebody's response to weight gain. This result suggests that lean animalsincrease their production of leptin to return their weight to the setpoint," explains first author Jeffrey L. Halaas, B.S., biomedical fellow atRockefeller...Low Oxygen, Key To Fetal Development, Also Offers Cancer Clues
...erCenter, since hypoxia, or low oxygen level, also plays a role incancerous growth -- a process remarkably similar to placentaldevelopment. The study grew out of Fisher's longstanding interest infetal and placental development. A few clinical ultrasoundstudies, including some at Rochester under the di......mary chemical messengers, orneurotransmitters, and plays numerous complex roles in both movement andemotion... to shedding light on therole that the D4 receptor plays in an organism*s response to drugs like alcohol,cocaine and methamphetamine, the new research report......, appearedcompletely healthy. "This enzyme clearly plays a primary role in the developmentof the disease in mice and probably in humans," Shapiro says. Macrophage elastase is a member of a family of enzymes that is currentlyattracting intense scientific interest. Many researchers believe that membe...