Other highlights in the August 4 JNCI
...press the gene HER-2/neu are more likely to have a poor clinical outcome. A new study finds that HER-2/neu...rapy for Neuroblastoma in Mouse Model Survival is poor in patients with advanced-stage neuroblastoma, a cancer of nerve cells in infants and children, and ...Study shows impact of emotionally healthy fathers when mothers' poor mental health affects children
...tially reduce the negative influence of a mother's poor mental health on a child's behavioral and emotiona...hers also found that when a mother and father have poor mental health, the influence on a child's behavioral problems is particularly strong for boys. "Many...Pocket gophers serve as 'ecosystem engineers'
...s with most burrowing mammals, pocket gophers have poor eyesight. However, they compensate for this with other, well-developed senses, such as large whiskers, which are sensitive to movement and help them in dark tunnels. They have powerful claws and teeth for digging. They are vegetarian, or herbivores, ...LA BioMed Medical/Research Briefs, July/August 2004
... Chelbowski says: "Ethnicity had a major effect on poor prognosis cancer risk. In black women, a higher proportion of breast cancers are diagnosed with unfavorable characteristics." Dr. Chelbowski points out that genetic and biochemical factors may be the source for those high-grade, receptornegative can...Save the rainforest - eat a tree
...ees with low defenses [against insects] to live in poor white sand soils." Coley says: "Most people think of herbivores as detrimental pests bugs eat plants, which is not good for the plants. Yet without insects, clay tree species would take over all forest types. Bugs beget tree diversity." ...Scientists discover new intricacies in how ulcer bugs stick to stomach
...ed nations, where the bacteria's pervasiveness and poor sanitation significantly increase the risk of repeat infections. In addition, resistance to standard drug therapies is a major problem in these countries. H. pylori can survive in human stomachs for decades, employing many tricks to do so. To avo...Microarrays, key genome expression trackers, work better when probes are sequence-verified
...cer that differ in their prognoses. Unfortunately, poor reproducibility of results exists across studies. Furthermore, there is now a tremendous volume of data, particularly from human clinical specimens, which can't be duplicated, so strategies to improve analysis of (that is, "clean up") existing data s...Living at home helps young mothers stay in school
...ddler. Thus, instead of being a causal factor for poor parenting, living at home is a marker for young mothers who are at risk for poor parenting. On the other hand, our results suggest that more schooling may be a real outcome of stayi...Carnegie Mellon neuroscientist develops tool to image brain function at the cellular level
...se methods have worked at the gross level and with poor resolution, according to Barth, an assistant professor of biological sciences at the university's Mellon College of Science. To overcome these limitations, Barth created a transgenic mouse that couples the green fluorescent protein (GFP) with the gen...Chemoradioimmunotherapy for advanced breast cancer: hope for the future?
...ncer, with metastases to lung and bone, has a very poor prognosis and current treatment protocols for this...f less than two years. One of the reasons for this poor prognosis is that metastatic cancer cells are less responsive to treatment than primary tumour cells...Brightness discrimination in the dog
...aylight. Griebel hypothesizes that the relatively poor brightness discrimination ability of these arrhythmic animals represents a compromise. Because their visual systems have to operate under a wide range of light conditions, something has to be given up. She says this idea is an initial supposition, an...Early predictor of breast cancer aggressiveness
...on of cells is less active in breast tumors with a poor prognosis than those that are less aggressive, res...pression indicates a more aggressive phenotype and poor prognosis." They suggest that quantitative PCR, to measure the number of ALCAM transcripts in a tiss...Noah's modern ark: The role of ART in conserving endangered species
...es, on the two continents. Pandas are notoriously poor breeders in captivity, with only a three-day period of fertility a year. Baby pandas have been born after AI using cooled as well as thawed sperm, and from males with terminal disease. The successful multi-dimensional management programme shows the...Clinical judgement still counts strongly alongside genetic testing
...d. And a genetic diagnosis may include a poor prognosis, or be seen to have grave ramifications for other, including future, family members. ...Study sheds new light on genetic risk for Parkinson's disease
...l Alzheimer's disease and has been associated with poor clinical outcome in people with acute head injury ...ou may be at higher risk of Alzheimer's disease or poor recovery from stroke and brain injury." On the other hand, APOE-2 seems to occur with lower ...European Commission approves Herceptin + Taxotere as 1st-line therapy in HER2-positive breast cancer
...ve form of breast cancer which traditionally has a poor prognosis. The approval is based on study results(1) which showed that for women with HER2-positive breast cancer, the combination of Herceptin and Taxotere significantly improved median life expectancy by more than one-third (31 months with Hercep......m London to Africa? "By mid-century, millions more poor children around the world are likely to face displ...thout saying that the vulnerability of the world's poor will be multiplied many-fold if global warming causes significant melting of one or both of the pola...Scientists characterize new breast tumor subtypes with poor clinical outcomes
...type of estrogen positive breast tumor with a very poor outcome, work that does much to explain why a small percentage of estrogen positive tumors do not have a good outcome. Dr. Perou says the ability to classify tumors into subtypes is made possible by microarray analysis, a technique that allows scie...'Rolling Store' provides model for overcoming barriers to healthy foods and better health outcomes
...ic and transportation barriers in order to provide poor women in the Lower Mississippi Delta access to hea...ng Store project, and its potential as a model for poor communities, on June 14 at the annual meeting of the American Society for Biochemistry and Molecular...Breast cancer patients failed by treatment with taxol and taxotere respond to abraxane
...ane therapy. The patient population studied had a poor prognosis with 91 percent having visceral (lung and liver) disease, 65 percent with more than three metastatic sites and 88 percent demonstrating ongoing tumor growth while on Taxol or Taxotere. "The activity of Abraxane and the tolerance of the we...