Researchers determine genetic cause of Timothy syndrome
...form of autism in those affected, and there is the possibility that understanding more about the nature of these calcium channel defects could improve understanding of autism, which affects 200,000 to 400,000 children in the United States. Calcium channels are pore-like proteins that nestle in cell membranes and...New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...motherapy. What this means is that we now have the possibility of offering APL patients a new first-line treatment that avoids conventional chemotherapy. It also means that if we have this drug and other effective drugs such as ATRA available as well, most patients will be able to avoid the need for bone marrow ...Award winning researchers reveal potential new role for Glivec
...h was very high grade and where there was also the possibility that it may not have been a true DFSP, but our patient without the translocation did not respond to imatinib. Nevertheless, our data support the use of imatinib where t(17-22) is detected, although our findings cannot be used to make any definite sta...Punching the timeclock of life
... striking, he said, is that the findings raise the possibility that the same process happens in humans, with many of us dying before we have to. "Programmed human aging is just a possibility. We don't know whether it's true yet or not," he said. "But if aging is programmed in yeast, and the pathway is v...Prion propagation: Avoiding the toxic oligomer
...y cause disease. Weissman and colleagues raise the possibility that creating conditions that favor fiber growth while inhibiting oligomer formation might limit the toxic effects of amyloid plaques. The approaches outlined here should lay the foundation for exploring these questions in higher organisms. ...Amyloid fibers sprout one step at a time
...being key intermediates in fiber formation. Such a possibility could have implications for treating amyloid diseases such as Alzheimer's and Parkinson's, he said. "Investigators are now screening for drugs that would prevent amyloid from forming, to treat these disorders," said Weissman. "While it is quite spec...Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
...tically modified oilseed crops. In addition to the possibility of providing healthier, more nutritious oils for human consumption, this work will lead to the production of high quality animal feed that could improve the PUFA content of animal products such as meat, eggs, and dairy foods....Sugar-coated sea urchin eggs could have sweet implications for human fertility
...hes to contraception. The research also opens the possibility of studying other functions of carbohydrate-signaling molecules. The sugar chains in sea urchins are similar to some found in algae that have a variety of possible medical uses, as anticoagulants and antiviral agents, for example. The research was s...Blue marlin in gulf have high mercury levels, A&M study shows
...ent years and several articles have focused on the possibility that oil and gas platforms in the Gulf of Mexico are the major source of the mercury problem in the Gulf. To investigate the source question, Rooker, Gil and Cai are examining mercury in pelagic fishes from areas with high concentration of petrochemi...The search for a kinder, gentler chemotherapy
...lls that happen to take in the nanoparticles. "The possibility for using these nanoparticles as vehicles to target and kill only cancer cells is particularly exciting," said Jean Chmielewski, professor of chemistry at Purdue University. "Decorating the exterior of the vehicle with folic acid is a very direct rou...Sandia experiments may reduce possibility of future water wars
... amount of water needed for it and thus lessen the possibility of international conflict is extremely important to the security of the United States and the world." The potential savings in water is particularly important in New Mexico and the American Southwest, Mexico, water-parched regions like the Middle ...Essential smell gene may provide key to new insect repellents
...ed "locks" in which odorant molecules fit. Another possibility is that Or83b acts as a chaperone to direct other receptors to their proper placement in the cell. Or Or83b may be essential to the series of molecular signals that trigger perception of a scent. "The reason this is really important is that we've re...Pig-human transplantation not PERVerted
...s. A major concern of xenotransplantation is the possibility of transmitting pathogens from these other species into the donor. Particular attention, for the case of transplantation of tissues and organs from pigs, has been paid to a set of pig-derived viruses called PERVs (for Porcine Endogenous RetroViruses)...JCI table of contents: 1 September, 2004
...gs. A major concern of xenotransplantation is the possibility of transmitting pathogens from these other species into the donor. Particular attention, for the case of transplantation of tissues and organs from pigs, has been paid to a set of pig-derived viruses called PERVs (for Porcine Endogenous RetroViruses)...Protemix corporation announces discovery of way to repair hearts damaged by diabetes
...the mechanisms of the disease. There is a distinct possibility for intervention and treatment. This work needs now to be transferred into larger scale clinical trials. It has been assumed since the beginning of time that heart muscle will not regenerate. This work refutes that.' 'This is great news for biotechno...Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
...re are clear indications that we need to take that possibility seriously," said Dr. Dieudonn Ankara, GRASP Focal Point for Congo-Brazzaville, who confirmed these recent developments. "This situation demands serious attention, since another Ebola outbreak would have devastating effects not only for wildlife, but ...Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
...osed. Research at the universities suggests the possibility of developing a biological pacemaker, one that can vary the heart's beats to fit the body's needs, as is required during variations in exercise or emotion. "The opportunity to translate this important technology from basic research into human thera...Tiny molecules have big potential as cancer drugs, Stanford researcher believes
...rd University School of Medicine points toward the possibility of a different type of cancer drug small molecules that would home in on the proteins tumors need without poisoning patients. Matthew Bogyo, PhD, assistant professor of pathology, will discuss his studies of some of these molecules at an Aug. 24 tal...Genetically-engineered 'marathon mouse' keeps on running
...ass," said Evans. "Going into this experiment, the possibility of an effect on muscle fibers was not on our radar screen." However, when the researchers produced mice with enhanced PPAR-delta activity, they saw a major transformation in skeletal muscle fibers. The mice showed a major enhancement of so-called "s...... of private property restrictions. There is a real possibility that this culturally and economically significant art form may disappear if basket makers cannot find a reliable and affordable source." The researchers interviewed basket makers at home or at the roadside stands where they sell their wares, asking o...