Pitt Researchers Develop Strategy To Use Dendritic Cells To Treat And Prevent Tumors
...ve been identified. "It has not yet been possible to make "customized" therapeutic vaccinesfor indiv...ty to the tumor," suggested Dr. Falo. "One possible advantage of the co-culture vaccine approach over fusionbased treatments or other existing tumor cel...New Test Opens Window On Corrosive Free-Radical Activity In Individuals
... technical underpinnings needed for a widerange of possible studies to come. Among these might be large-scale clinicaltrials of antioxidant vitamins. The laboratory of chemist Joshua Rokach, PhD, at the Florida Instituteof Technology collaborated with FitzGerald's group on the study. Primary fundingfo...Study Finds Some People Are 'Born To Smoke'
...." The study also suggests that someday it may be possible to identify a cluster ofcharacteristics that go hand-in-hand with sensitivity to nicotine, or to developa test for biological sensitivity. Once there is a simple way to identifychildren at high risk of becoming smokers, they can be targeted for spec...Microchip Sensor Detects Bacteria
...logical problems. "This is just one example of the possible use of nanofabrication technology for biological applications," says Craighead. Batt points to the enormous challenge of detecting bacteria at every stage in the food processing industry. "As history has shown us, if a small colony of bacter...Spinal Cord Injury Treatment May Improve With New Findings On Nervous System Damage
...cal trials to evaluate safety, and it soonmight be possible to test their effectiveness against central nervous systeminjury. "Preserving the function of just a small fraction of the damaged longcables that go down the spinal cord could provide meaningful improvement inday-to-day function for people w...First Evidence That Localized Arthritis Gene Therapy Heals Distant Diseased Joints
...r systemic, effects. Our hope is that it would be possible toinject one arthritic joint in a patient with a therapeutic gene and find thatarthritic joints elsewhere in the body respond to this therapy," said SteveGhivizzani, Ph.D., a post-doctoral fellow in the department of moleculargenetics and biochemistr...Obscure Enzyme May Play Major Role In Heart Disease
...at the discovery of this enzyme's activity opens a possible new routeto prevention of heart diseases. The real function of the enzyme has been something of a mystery since itwas discovered more than 40 years ago. Its previously known function was tobreak down organophosphates, chemicals that are used ...Researchers Discover How Ulcer Bug Becomes Antibiotic-Resistant
...e researchers' findings also raise concern about a possible linkbetween the drug and stomach cancer in people infected with H. pylori. "The real danger lurks when a person takes metronidazole without the complete complement of drugs that eradicate this bacterium," says Paul S. Hoffman, Ph.D., professor of mic...Agriculture and urban activities impact water quality in the South Platte River Basin
...ances may be needed to protect water resources for possible future use as a drinking-water supply. The good news from the USGS report is that surface and ground water inthe forested mountain areas are generally of good quality and relatively unaffected by humans. Mining activities and residential dev...Environmental Technology Breakthroughs Forecast -- Year 2008
...c carbon. Lightweight Cars--Squeezing every ounce possible out of cars will mean a familysedan that gets at least 80 miles per gallon of gas, generates less pollutionand uses less gas. Lighter cars will be built with less steel and morelightweight aluminum, magnesium, titanium and composites. Advanced metal...Naturally Produced Enzyme May Be Useful In Inflammatory Arthritis
...einflammatory effects of these peptides, it may be possible to stimulatesynovial cells to make more of their own NEP,” Ward said. He and hiscolleagues suggest that gene therapy may be used to insert a gene that controlsNEP production. The extra levels of the enzyme could then degrade inflammation-...Duke Researchers Genetically Engineer Mice To Block Heart Enlargement
...the team. "Our hope is that by demonstrating it is possible toblock this initiation step, we will eventually b... pressure overload hypertrophy, wethink it will be possible to design a single drug or gene therapy strategy to dothe work that many separate types of drugs acc......dding yeast in a UC San Francisco lab are yielding possible insightinto a key step leading to the creation of human sperm. And the finding, saythe UCSF researchers, could ultimately pave the way for an understanding of whyhuman sperm sometimes doesn't fully develop, causing sterility. In their stud......human range. However, to correct for possible differences in the size of the tonguescontrolled by the nerves, the scientists plotted canal size versus the size ofthe oral cavity. Still, the apes and Australopithecus samples measured abouthalf the relative size of those of humans and Neanderthal...New RNA Repair May Lead To More Successful Gene Therapy
CHAPEL HILL - A possible new form of gene therapy designed to maskgenetic mutations - instead of cutting away and replacing them -- has beendeveloped by scientists at the University of North Carolina at Chapel HillSchool of Medicine and Bern University in Switzerland. ...Homocysteine: A Possible Risk Factor For Alzheimer's Disease
...e they provide atestable hypothesis that it may be possible to prevent or delay the progressionof Alzheimer's disease in a proportion of potential sufferers. However, testingthis hypothesis will require long and costly trials.' A full paper describing the results of this study is being considered forpublicati......threeyears. Funding for the study was made possible by Johnson & Johnson and theNational Institutes of Health....High-Altitude Cerebral Edema Likely Caused By Leaks In Blood-Brain Barrier
...ies to leak. In addition, Krasney said, it is possible that, in the presence of hypoxia, another chemical messenger, cyclic guanosine monophosphate (cGMP), acts with nitric oxide, a vasodilator, to promote and sustain permeability of the blood-brain barrier. The combined influence of actions could allow......e presynaptic calcium channels, and thus it became possible to address the question whether R-type channels are at the presynaptic terminal. Simultaneous recordings of the presynaptic Ca2+ influx and the excitatory postsynaptic current (EPSC) evoked by a single action p......od is imperfect,so scientists have looked at other possible solutions for ships, includinginstalling powerful on-board filtration systems. As for the invaders who havemade it into American waters, solutions range from the standard ? such aschemical treatments for zebra mussels ? to the exotic ? such as introd...