Tag: "postmenopausal" at biology news
Safety of isoflavones in dietary supplements targeted by Illinois initiative
...cancerous cells in animal models representative of postmenopausal
women with estrogen-dependent breast cancer. "Under the grant, three groups will conduct preclinical investigations on animal models, looking for a balance of potential effectiveness and safety issues," Helferich said. "We will look at how differ...
Certain genes boost fish oils' protection against breast cancer
...udy. The researchers had already found that among postmenopausal
women in this group, those who ate the most n-3 fa...g to which polymorphisms they had. They found that postmenopausal
women who had low-activity versions of genes associated with GSTs (known as GSTM1, GSTT1 and GSTP1) ...
Select research highlights from current AACR journals
...s used to treat hormone-dependent breast cancer in postmenopausal
women pack a significant beneficial side effect in laboratory animals. Exemestane and letrozole was shown to significantly prevent bone loss, enhance bone mechanical strength and lower serum cholesterol levels. The inhibitor drugs act by interfering ...
Other highlights in the August 4 JNCI
...lesterol--are associated with an increased risk of postmenopausal
breast cancer in overweight and obese women, accor...lesterol were associated with an increased risk of postmenopausal
breast cancer in women who were overweight or obese. The association was strongest in women who gain...
Animal research suggests plant estrogens in soy do not increase breast cancer risk
...t increase the risk of breast or uterine cancer in postmenopausal
women. "This is convincing evidence that at dieta...ut whether high levels of dietary soy are safe for postmenopausal
women. Soy products are sold as a natural alternative to traditional hormone therapy. The most commo...
Donaghue Women's Health Investigator Program awards grants to three at Yale
...nce understanding of the neurobiology of peri- and postmenopausal
depression and may have profound effects on the treatment of depression during this stage in women's lives. The Ethel F. Donaghue Women's Health investigator Program at Yale was established with a grant from The Patrick & Catherine Weldon Donaghue M...
Obesity and hypertension: Two epidemics or one?
...tion resulted in dramatic reduction in BP in obese postmenopausal
women. 7. Pharmacological therapy of obesity hypertension. There are currently no specific recommendations for the pharmacological treatment of obesity hypertension, although some have suggested that the selection of therapy should be based on ...
Moderate alcohol consumption increases plasma levels of a protective hormone
...rs after that of men, which seems to be related to postmenopausal
factors. So, this study's examination of the impa..." For this experiment, 10 middle-aged men and nine postmenopausal
women all considered healthy, non-smoking, and moderate drinkers consumed either regular beer or n...
Soy processing influences estrogen-dependent breast cancer growth in mice
...eclinical investigation are especially relevant to postmenopausal
women with estrogen-responsive breast cancers who are looking for alternatives to HRT," he said. In the study, mice were fed equal concentrations of the soy isoflavone genistein, allowing Helferich to determine the influences that various bioactive...
In male monkeys, too much soy has adverse effects
... cancers, osteoporosis, cardiovascular disease and postmenopausal
symptoms, less effort has been invested in charact... soy is the most widely used botanical by pre- and postmenopausal
women. "To the best of our knowledge, the present study may be the first to demonstrate that long...
Exercise reduces blood estrogens, risk for breast cancer in post menopausal women
...eek significantly reduced circulating estrogens in postmenopausal
women, according to a new study published in the c... breast cancer. "Exercise is an effective way for postmenopausal
women to increase their chances of avoiding breast cancer," said Anne McTiernan, M.D., Ph.D., a memb...
Preoperative treatment with Arimidex(TM) allows patients to undergo less extensive surgery
... tolerability profile in the adjuvant treatment of postmenopausal
women with early breast cancer 3,4 . Furthermore,...e treatment in endocrine breast cancer therapy for postmenopausal
Astrazeneca announces EU marketing approval for Faslodex(TM)
... The novel drug is indicated for the treatment of postmenopausal
women with receptor-positive locally advanced or m...e inhibitors and tamoxifen are standard therapy in postmenopausal
women with advanced breast cancer, providing an effective and well-tolerated treatment option. Howev...
Other highlights in the March 3 issue of JNCI
...hey looked at 15 years of follow-up data on 34,708 postmenopausal
women ages 55 to 69 who completed a food-frequency questionnaire for the Iowa Women's Health Study. The authors found that the relative risks for proximal colon cancer increased more than twofold across categories of heme iron intake and the corresp...
Other highlights in the February 4 issue of JNCI
...sitive and ER-negative breast cancers with age and postmenopausal
hormone use, and of PR-positive and PR-negative breast cancers with reproductive history and body mass index after menopause. The authors concluded that incidence rates and risk factors for breast cancer differ according to both ER and PR status; thu...
Highlights of Tufts University nutrition research: January 2004
...tudied a small group of men over the age of 40 and postmenopausal
women with moderately elevated cholesterol levels. For an initial six-week period, the study participants consumed an average American diet (AAD) that was relatively high in total fat, saturated fat and cholesterol similar to diets consumed in the ...
OHSU team discovers compound that lacks estrogen's risks
...se as an alternative to estrogen treatment used by postmenopausal
women to relieve symptoms of menopause, such as ho... effective at maintaining cognitive performance of postmenopausal
women. "Women that don't have hormone replacement therapy have been known to have more cognitive i...
New advances in thrombosis help further understanding of disease prevention
... of death, disability, and poor quality of life in postmenopausal
women cardiovascular disease, cancer, and osteoporosis. One of the WHI studies was a clinical trial that included 16,608 women aged 50 to 79 who were randomized to receive either conjugated equine estrogen (0.625 mg per day) and medroxyprogesterone...
Estrogen receptor-a disruption and vasodilation in coronary arteries
...uces the risk of cardiovascular disease in healthy postmenopausal
women. Estrogen enhances endothelial function of the coronary arteries, and this may contribute to the cardioprotective effects of the female hormone. The precise mechanisms that mediate the beneficial effects of estrogen on arterial endothelial func...
Variants of BMP2 gene as genetic risk factors for osteoporosis
...n independent replication study with two groups of postmenopausal
Danish women--one group with low BMD and one with osteoporotic fractures--found comparable results, with a higher incidence of the BMP2 variants associated with osteoporosis in Iceland in the affected Danish women compared to the controls. Taken to...
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