Study explores safety of low-dose radiation
...de us in unstable forms of common elements such as potassium and hydrogen - cause problems and exactly what genes and proteins in the body help repair and, more importantly, prevent damage. "The reason to do this in fish is to look at mechanisms of injury and innate mechanisms for repair and protection," Dr....Calcium channel involved in coronary artery relaxation
...laxation of blood vessels is the calcium-activated potassium channel. When these channels open, potassium ions exit the cell, triggering an inhibition of contraction. "We propose that the calcium influx fr...Calcium channels control coronary artery relaxation
...ch had shown that an entirely different channel, a potassium channel, plays a key role in regulating muscle rel...owing through T-channels might somehow "fine-tune" potassium channels. Findings from two of their experiments supported this idea, said Campbell. A drug that ope...Easily paralyzed flies provide clues to neurodegeneration
... labs worldwide are now investigating Herg and the potassium channel protein it encodes. Such discoveries have engendered significant interest on the part of the pharmaceutical industry. For instance, in the United States all drugs now headed to market must be screened to ensure that they do not perturb...Scientists identify molecular step that causes intoxication
...a channel-like protein in the brain that can allow potassium ions to pour out of neurons, a normal process that...re and his colleagues, technically known as the BK potassium channel, is one of more than 200 known channels that regulate cell activities by controlling the flo...JCI table of contents, 16 February 2004
...e in which the small-conductance calcium-activated potassium (SK) channels regulators of firing frequency in the DCN were silenced. The authors found that these neurons had an increased firing rate and the mice were ataxic. Importantly, the Purkinje cells input into the DCN remained intact and no other signs...Best way to clean up toxic plumes? Give 'em a pill
...uried 30 to 40 years ago. "But most people who use potassium permanganate to treat pollution pump it into a wel...ical sciences at Ohio State University. Like salt, potassium permanganate is granular and dissolves when it comes into contact with water. "There's often no cont...JCI table of contents, 2 April 2004
...xt. TITLE: Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension AUTHOR CONTACT: Miguel A. Valverde Universitat Pompeu Fabra, Barcelona, Spain. Phone: 34-93-542-2832 Fax: 34-93-542-2802 E-mail: miguel.valverde@edu.upf View the PDF of thi...New method for determining age of artifacts fills chronological gap for scientists
...rganic material up to around 50,000 years old, and potassium argon dating is good for dating mineral samples that are between 100,000 and 4.3 billion years old. Forged artifacts also can be tested with the quartz hydration dating technique. With replications of statues for example, the thinness or lack of th......tain steady levels of materials such as sodium and potassium in the bloodstream. To sustain control, these organs employ a gradient a rising concentration of sodium from the outer layer, called the cortex, (where concentrations are around those of normal body tissues), towards the center, where levels reach u...Searle Scholars program awards $240,000 to UT Southwestern researcher
...channels control the flow of ions, such as sodium, potassium and calcium, across the cell membrane. Their function underlies many biological processes, including the excitation of nerve and muscle cells, the secretion of hormones, and sensory transduction. An Endowed Scholar in Medical Science at UT South......s recent experiments with degenerate gases of cold potassium atoms in the "crossover region," in which the interactions between atoms can be tuned by varying the external magnetic field (G2 3). And Anthony Leggett of the University of Illinois will offer some reflections on the theory of this crossover region,...Pump failure implicated in a form of dystonia
...y genetic flaws in a protein that pumps sodium and potassium across the membranes of neurons have been implicat...c subunit in a larger enzyme that pumps sodium and potassium across the membranes of neurons, using the energy of ATP to do so. Such transport is critical to mai...Epilepsy: Signals 'brake' in brain impaired
...channel, which is permeable for positively charged potassium ions. This channel is mainly located at the signal...re able to show: on the one hand the genes for the potassium sluice are read less often, with the result that the cells produce fewer Kv4.2 channels. On the othe...Commercialization deal boosts hope for new sickle-cell drug
...hannel, known as the Gardos channel, through which potassium and water exit the cell. Blockade of this channel keeps the cells hydrated, resulting in much less sickling. The CHB researchers also discovered that clotrimazole has metabolites (breakdown products) that can reduce sickling without the liver...Heartless worms hold clues to cardiac arrhythmias, sudden death
...ing tool to identify novel protein regulators of a potassium channel involved in the rhythmic heartbeat. They r...thmias and sudden death associated with block of a potassium channel called HERG (Human ether-a-go-go related gene). Many therapeutic drugs -- antihistamines, a......or Stephenson said. 'When a muscle is worked hard, potassium ions come out of the fibres and make the membrane less excitable. The acidity generated inside a working muscle helps counter this depressing effect by reducing the influence of chloride, which helps the muscle membranes stay excitable.' 'It is a ver...