"Genetic Factors Influencing Cholesterol Response To Diet"
...e ratio of total cholesterol to HDl cholesterol, a powerful index of heartdisease risk. Studies in families have suggested that this response may be due to anunderlying genetic predisposition to the pattern B trait that only becomesevident when dietary fat intake is reduced to a sufficiently low leve...New Sensor Will Detech Chemical And Biological Pathogens At Incredibly Small Doses
...is device has showed results that are 20 timesmore powerful than previous sensing devices. Velander, a biochemical engineer who heads Virginia Tech's Pharmaceutical EngineeringInstitute, teamed with Kent Murphy, a fiber optics expert and a member of theelectrical engineering department, to develop the prototy......bandoned, but this research showsangiogenesis is a powerful therapy to be used with bypass surgery." The procedure is still experimental, but scientists say the use of FGF-Imay particularly benefit patients whose blocked vessels cannot be treated bycardiac bypass operations. "At the ...Pharmacogenesis: Postgenomic Drug Discovery Through Developmental Biology
...between specificgenes and disease processes. This powerful technology enables researchers toselect and validate optimal therapeutic targets. On March 26 and 27 in Boston, Mass., more than 25 of the leading developmentalbiology researchers and clinicians will describe the field's history and growth,present c...PEBBLEs Help U-M Scientists Open A Window On Cell Chemistry
...olecules. "PEBBLEs are self-contained sensors powerful enough to detect even slight changes in cell biochemistry, but small enough to avoid damaging the cell," said Heather Clark, a U-M graduate student in chemistry. Clark is part of a U-M team currently developing and testing the biosensing devices in ...3-D Structure of Human Tumor-Suppressor Protein Produced
...molecule’sstructure. NMR spectroscopy uses a powerful magnetic field to make molecular measurements.The method enables the researchers to study the structure of the p16 proteinin a water solution, which more closely represents the molecule’s structureas it would exist inside the cell. This, in tur...Study Of Microbes May Hone Predictions Of Mining Impact
... conditions the microbes thrive in nature can be a powerful new tool to predict the effects of sulfide mining at a given site, said Katrina J. Edwards, a UW-Madison graduate student and a co-author of the study. Prior to the new study, conducted at Iron Mountain, Calif., an abandoned and heavily polluted iron......cedented rate of climate change. One of the most powerful tools at the disposal of researchers is the use ofsophisticated computer models that now incorporate information on how speciesestablish, grow and reproduce. Dr. A.M. Solomon (Environmental ProtectionAgency, USA) and co-workers developed such a model...Lights, Camera ... Reaction: Charting The Biological Effects Of Light InBillionths Of A Second
...asphotosynthesis and vision. It also may suggest a powerful new mechanism for thedevelopment of optical computers. The ability to record this ultra-rapid conversion results from a recent,million-fold improvement in time resolution of X-ray measurements that can nowrecord changes in the shape of the working pr...RNA-Dendritic Cell Combo Shows Promise As A Universal Cancer Vaccine
...18 test tube experiments. "This is a very powerful response compared to what has been seen inother cancer vaccines," said the scientist who led the study, Eli Gilboa,research director of the Center for Genetic and Cellular Therapies at Duke."It's a pre-clinical study that shows the vaccine can work v...Insect Taste Buds Target Of Control Method
...ve that they will feed exclusively on it, or by a powerful antifeedant....New Test Opens Window On Corrosive Free-Radical Activity In Individuals
...the two assays corroborateeach other and provide a powerful set of tools to address the role of freeradicals in health and disease. "Do healthy people derive any benefit from taking antioxidants if theyhave a strong native antioxidant defense?" asks Garret A. FitzGerald, MD,chairman of the department ...Researchers Discover How Ulcer Bug Becomes Antibiotic-Resistant
...cterium converts metronidazole to hydroxylamine, a powerful mutagen, and use of metronidazole again in later therapies selects for these newly resistant mutant variants." Metronidazole-resistant strains often arise in people who have neverbefore been treated for H. pylori infection but who may have ta...Fruits And Vegetables Protect Lungs
...y fat, race, income and cigarette smoking, provide powerful evidence "that antioxidant nutrients play a role in maintaining lung function in adults and suggest that the effects of the antioxidant component differ according to smoking status." In the Chinese sample, the researchers found that those with higher...Electron Accelerator Provides Unique Proof Of Gene Repair Process In Living Cells
... lithography may someday result in a smaller, more powerful computer chip. "We wanted to break chromosomes in a tiny area of the nucleus of a living human cell without blasting it away," said Petrini. "The electron accelerator at the Synchrotron, which generates so-called 'ultra-soft' X-rays that are extremel......chanism," Holtzman says."These mice will provide a powerful way of exploring the role of human apoEisoforms produced in the brain and their influence on brain diseases." Sun Y, Wu S, Bu G, Onifade MK, Patel SN, LaDu MJ, Fagan AM, Holtzman DM. GlialFibrillary Acidic Protein-Apolipoprotein E (apoE) Transgenic ...Mussels Muscling In, Crabs Pinching Native Species
... possible solutions for ships, includinginstalling powerful on-board filtration systems. As for the invaders who havemade it into American waters, solutions range from the standard ? such aschemical treatments for zebra mussels ? to the exotic ? such as introducingparasitic barnacles that make green crabs ste...New Study Shows White Males Have More Receptors For Patent Blood-Vessel Contracting Substance
...matic differences in the density of receptorsfor a powerful and naturally occurring blood-borne substance calledendothelin-1. And it's more bad news for white males. "We won't entirely know the relevance of this study until we do the sameexperiments with arterial tissue, but it's an important first st...ACE Gene Linked To High Blood Pressure In Men But Not Women
...ramingham HeartStudy report, linkage analysis is a powerful tool for scientists to identify agene region, called a locus, that is involved in specific disease. However, thestudies cannot distinguish whether the ACE variant or another gene that is alsoclosely linked to ACE is responsible for raising blood pre...New Vancomycin Structure May Point To Path For Overcoming Antibiotic Resistance
...y a strain of bacteria resistant tovancomycin, the powerful antibiotic physicians turn to when others fail. The manwas only the fourth known case in the world of resistant staphylococcus aureusinfection, and government officials are minimizing the danger to public healthrepresented by this first fatality. Sti...