Fruit Flies May Shed Light On Cocaine Addiction
...ue of CurrentBiology. Cocaine is one of the most powerfully addictive street drugs. Extensive studieson rodents and monkeys have provided little information about the molecularprocesses that underlie cocaine's behavioral and addictive effects. Using fruitflies in such studies offers several advantages. The...Higher Levels Of Protein May Predict Heart Disease
...emonstrate that low-levelinflammation in adults is powerfully connected to measures of insulinmetabolism, according to George Howard, professor of public health sciences(biostatistics and epidemiology) at the Wake Forest University School ofMedicine. The loss of sensitivity to insulin is believed to be ...Disconnecting molecular handbrakes has drastic consequences
...lso, he said, more subtle SOCS1 malfunctions may powerfully affectthe immune system. "When you knock out a gene, as we did with SOCS1 , yousee the black and white of its function. But what if there are people withmutations that make their SOCS1 a little bit less efficient? Given thisgene's critical role in...Drug treatment interruptions boost immune response to HIV in Patients
...t followed, his immune system responded even more powerfully against the HIV virus. When last checked four months later, his virus levels remained very low. Patient C-13s experience is reminiscent of the report published in May 1999 in the New England Journal of Medicine, describing a recently infe...Community HIV urine testing program proves powerfully effective
...e proven that community-based testing programs are powerfully effective in reaching people at high risk for HIV. In a report prepared for this week's 8th Annual Conference on Retroviruses and Opportunistic Infections, Hopkins researchers said tests of nearly 1,000 people at community sites over a year and a hal......than 20 feet. Besides their human toll, the storms powerfully altered the nation's largest lagoonal estuary, Pamlico Sound, new studies show. They flushed unprecedented amounts of nutrients and sediments into this key Mid-Atlantic fisheries nursery, sickening and killing countless thousands of fish and shellfis......st molecular evolutionary study that seriously and powerfully says the paleontologists have been right all along in grouping mammals the way they did," said Killian. "It turns out that common sense is correct." The Duke scientists realized the power of using large nuclear genes for molecular evolutionary st...Common pediatric anesthesia drugs cause brain damage and learning and memory problems in infant rats
... to enhance GABA activity. They found that alcohol powerfully triggers nerve cell suicide in the developing brain, providing a likely explanation for the learning and memory disturbances associated with the human fetal alcohol syndrome. More recently, Olney and colleagues demonstrated that sodium channel blocki...Researchers discover common cause for aging and age-related disease
...ed diseases have proved elusive. In studies of the powerfully informative roundworm, C. elegans, UCSF scientists have discovered that a class of molecules found in the worms and in people can both prolong life in the worm and prevent the harmful accumulation of abnormal proteins that cause a debilitating Huntin...Small amounts of alcohol or anesthetics may damage the developing brain
... to enhance GABA activity. They found that alcohol powerfully triggers nerve cell suicide in the developing brain, providing a likely explanation for the learning and memory disturbances associated with the human fetal alcohol syndrome. "In all of these studies, we have found that drugs that enhance GABA inhib...