Tag: "precise" at biology news

Molecular Control Mechanism Of Embryonic Development Unraveled

...h DNA, Wolberger and colleagues have determinedthe precise way in which the proteins interact with one another to control development. Pbx1, by interacting with Hox proteins, is able to control theexpression of many different types of proteins, says Wolberger. "Understanding how they interact with partner p...

Researchers Find How Two Cancer Genes Interact To Cause Malignancy

...d to newtherapies, Nevins said. "Understanding the precise mechanisms that regulate these activities opens theway to developing therapeutics that specifically target the abnormal function,leaving the normal functions alone," he said. Other authors of the Molecular Cell study were Rosalie Sears and Gusta...

Nerve Cells On The Go

... of players, they still do not fullyunderstand the precise relationships among them. It is not as if a valve opened at the membrane, passing information allthe way to actin like water flowing smoothly down a tube. On the contrary, thereseems to be plenty of turbulence, with members of the pathway fr...

Artificial Gels Could Speed DNA Sequencing

...covering layer is deposited. This allows much more precise control of the height of the channel, he explained. The researchers are still at an early stage, running DNA samples through the biochip to see how fragments of different lengths can be identified. They mount the chips between two microscope slides...

Vastly Different Virus Families May Be Related

... 26 issue of the journal Molecular Cell, comesfrom precise determination of the three-dimensional structure of a key proteinmolecule, whose form suggests that all these viruses enter cells by a remarkablysimilar mechanism. "The structure of this molecule shows that a widely dissimilar virus, a virusthat ever...

Conservation Strictly By Numbers Can Be Risky

...s suffer from physics envy." But ecology is not as precise asphysics and we can't really predict what will happen to a given population based solelyon its size, he says. Wehausen assessed a 1990 model of the relationship between population size andthe likelihood of extinction in bighorn sheep. Developed by ...

Researchers Develop First Way To Immunize Against A Deadly Bacterium

...chers report. The scientists do not yet know the precise role of the bacterial protein theyhave blocked. They know it is needed for successful delivery -- or translocation-- of the toxin from the bacterium to the lung tissue, and that it itself is nota toxin, they report. Immunization could be useful not o...

Alzheimer's Disease And Developmental Biology Linked Through Single Molecule

...that presenilin may play a role in theappropriate, precise cutting of Notch. Two genes that code for presenilin were discovered in 1995 byinvestigators studying a particularly aggressive form of inherited Alzheimer'sdisease that strikes people as young as 30 years of age. Since then, researchershave ...

'Dual Control' Strategy Assures Accurate Cellular Marching Orders, But A Pathogenic Microbe Can Hijack The System

...l inputs for activation allows more controlledand precise cellular movements," an evolutionary advantage over a moreerror-prone one-signal system. The researchers also discovered that Listeria is able to mimic bothcellular aspects that attract Enabled. The microbe presents multiple copies of aprotein very ...

Vanderbilt Researcher: Human Brain Has Great Sense Of Timing

...ng band on the football field duringhalftime. With precise steps, some band members turn and march in a differentdirection than the rest, spelling out a school's letters or a mascot's shape. Scientists have known for years that to perceive figures against such a busybackground, human vision uses color, bri...

Protein Misfolding, Not Mutant Gene, Key To Lethal Sleep Disorder

...en in thefamilial form, it's the prion strain, the precise conformation of the misfoldedprotein, and not the variation in the gene that ultimately determines theconsequences of the disease." Familial fatal insomnia has been found in only <AHREF="http://brainpathology.upmc.edu/0398/83a15.htm">24 exte...

A sharper look at the brain

...n research. fMRI makes it possible to pinpoint the precise regions of themonkey's visual cortex (that region ...o be activated in the same manner.Similar but less precise patterns were found by the scientists in alert animalsespecially trained for this experimental set-u...

Fighting diabetes: UD researchers move closer to chip-based control of 'smart,' implantable insulin pumps

...automate the control ofblood-sugar levels." Highly precise control is important because sugar concentrations above thenormal level of 70 to 120 milligrams of glucose per deciliter of blood (mg/dl)have been associated with liver damage, blindness and other medical problems.And, cells begin to starve when bloo...

Jefferson scientists detail mechanisms of programmed cell death

By detailing the precise molecular pathways of apoptosis, or programmedcell...derstanding the chemical "recognition complex," or precise binding region,between caspase-9, and Apaf-1 (apoptotic protease activating factor-1), aprotein that...

New study establishes when pregnancy starts

...,North Carolina scientists have uncovered the most precise information yet aboutwhen pregnancy starts in humans. Fertilized eggs attach themselves to the lining of the womb six to 12days after ovulation, the research shows. In most successful pregnancies, thatimplantation - the real start of pregnanc...

Breast cancer cells shown to migrate toward hormone source - novel mechanism for metastasis seen

...mulates the progression of breast cancer, although precise details ofits action have been elusive. The current study describes a novelprolactin-mediated mechanism that may be a significant driver behindbreast-cancer metastasis and suggests new directions for the development ofdrugs that might block disease p...

Protein studies reveal sophisticated control of nerve communication

...naling control is much, much moresophisticated and precise than we thought." Scott and other members of his team, including Lorene Langeberg and IainFraser, collaborated with members of HHMI investigator Morgan Sheng's laboratoryat the Massachusetts General Hospital, describe their findings in the July 2,19...

Human Genome Sciences announces the discovery of a novel immune stimulant

...imulation and ultimately antibody production. The precise role of monocyteshas been a mystery. The discovery that monocytes produce BLyS, a substance thatstimulates B cell growth and activates antibody production, may be the answer tothis long-standing riddle. Potential Medical Uses of BLyS The potentia...

New UNC-CH study explains variations in onset of ice ages

...onomically controlled eventsshould occur on a more precise schedule, Rial says. Some suggested it waschanges in the plane of the earth's orbit rather than its shape that spawned theglaciers. Periodic dipping into a dust ring that also circles the sun might haveshaded and chilled the planet instead, they said...

Smog impacts: Hurtling through airways, tiny particles may do more damage than previously assumed

...But, additional research is needed to identify the precise mechanismsinvolved in particulate toxicity." To model fine particles moving through airways, the researchers analyzed datafrom clinical studies of people whose lungs were injected with a bolus ofparticles. Their study helps explain the impact of air ...

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