Nominations sought for AACR scientific awards and lectureships
...ize an individual or research team for outstanding preclinical research that has implications for the improved care of cancer patients. The award will recognize outstanding contributions in the fields of medicinal chemistry, biochemistry, or tumor biology as related to drug discovery and will encompass anticance...Grant funds research to develop tissue-engineered solutions for heart disease
...he body. Project scope will encompass in vitro and preclinical studies of tissue-engineered products. In addition, discoveries made in the course of this research could benefit tissue-engineering efforts aimed at disorders that involve other "mechanically active tissues," such as the bladder and urethra, said Dr...The mechanics of anti-tumor activity outlined
...e to 2ME2 when compared to Taxol or vincristine in preclinical models, it is the most more potent HIF inhibitor of all the microtubule-targeting chemotherapeutic agents tested that are used to treat cancer." The paper outlines the mechanism by which 2ME2 downregulates HIF; a finding that had not been previous...Programmable antibodies-- hybrid cancer therapy described by scientists at Scripps
...f both Kaposi's sarcoma and colon cancers in these preclinical studies. Moreover, this approach is general enough that it could be used to design hybrids against any number of cancers. "A single antibody can become a whole multiplicity of therapeutics simply by mixing it with the desired small molecule," says TS...Over-the-counter pain relievers effective in protecting against breast cancer
...s potentially limit breast cancer development, and preclinical studies have supported this finding by showing that they limit the growth of tumors in the breast. The primary mechanism of action of these drugs is the inhibition of COX-2, which is over-expressed in most human breast cancers. Recent studies indic...Project BioShield: Consistent financing, markets, indemnity for biodefense vaccine developers needed
...-generation injectable anthrax vaccine, as well as preclinical work on oral biodefense vaccines against anthrax a...gram (JVAP); An oral anthrax vaccine currently in preclinical development at AVANT, with support from a Small Business Innovation Research (SBIR) grant from the N...Cancer scientists to be honored by AACR during the organizations annual meeting in Toronto
...zes an individual or research team for outstanding preclinical research leading to the discovery of a significant new therapeutic agent for the improved care of cancer patients. Dr. Stevens' lecture, "Chemical Whispering and Drug Discovery: Matching Molecules and Mechanisms," will take place on Tuesday, April 8,...Alliance for Cancer Gene Therapy announces $1.5 million in national grants to young investigators
... to support basic research, technology innovation, preclinical validation and clinical translation to expedite development of effective and safe therapies for cancer. 100% of all funds raised by ACGT go directly to research. The primary recipients of ACGT Awards and Grants will be Young Investigators and Investi...Symposium on how 'nature and nurture' impact child development
... of depressed mothers. Important parallels to the preclinical literature will be highlighted, and finally, Dr. Newport will describe the clinical implications for the treatment of depressed mothers including its role as a primary preventive care measure for children exposed to the untoward effects of maternal d...UT Southwestern researchers developing new procedures to make bone-marrow transplants safer
...out companies. We make the immunotoxin, do all the preclinical studies, file and get an IND (Investigational New Drug Application) with the FDA, and do the clinical study, all on-site. We are hoping this will be a flagship for future efforts in this and related areas." Because a variety of disorders are treated ...AVANT to develop an oral anthrax and plague vaccine for U.S. Department of Defense
...-year period, covering vaccine development through preclinical testing. AVANT executed the subcontract with DynPort Vaccine Company LLC ("DVC"), the prime contractor for the Defense Department's Joint Vaccine Acquisition Program (JVAP). Headquartered in Fort Detrick, MD, JVAP is the lead Defense Department org...Acorda therapeutics receives NIH Phase 2 grant for central nervous system repair
...aturally occurring human IgM antibodiesfor further preclinical testing in multiple sclerosis (MS). Upon successfu...logy platform includes two remyelinating agents in preclinical development for MS. The first is M1, a class of human monoclonal antibodies, and the second is GGF2...Zengen, Inc. announces novel approach to reduce organ rejection
... molecules based on the larger a-MSH peptide." The preclinical study was designed to determine whether a-MSH treatment protects the allograft and prolongs survival in experimental heart transplantation, in the absence of immunosuppressive therapies. Donor cardiac grafts (Brown Norway) were transplanted into the...Inhibitor of novel cancer target, LPAAT-beta, demonstrates selective anti-cancer effects
...) today (Thursday 21 November) presented data from preclinical studies on a novel cancer target LPAAT-beta[1] in ...ed cells and in preliminary animal models. Through preclinical studies, CTI scientists found that LPAAT-beta is highly expressed in cancers of the lung, ovary, pro...Acorda Therapeutics acquires CeNeS neuregulin products
...s system in animal models. These antibodies are in preclinical development for multiple sclerosis. Additionally, Acorda is developing protein- and stem cell-based technologies for regeneration and repair of the spinal cord and brain. For further information please visit www.acorda.com . About CeNeS CeNeS is...Acorda Therapeutics receives L.W. Freeman Award for Scientific Research
...s system in animal models. These antibodies are in preclinical development for MS. Additionally, Acorda is developing protein- and stem cell-based technologies for regeneration and repair of the spinal cord and brain....Aspirin inhibits ovarian cancer growth, lab study finds
...rammed cell death, or apoptosis. USF continues its preclinical studies to determine how aspirin inhibits tumor cell growth. Dr. Becker said much more research must be done, including patient studies, before women are urged to begin taking aspirin to stave off ovarian cancer. Because there are few early symptoms,...Stanford researchers find cause, possible cure for gluten intolerance
... humans is a long way off and will require further preclinical work, Khosla said. "We think that this mode of therapy - peptidase supplementation - may offer hope in treating celiac sprue eventually,and we're going to test this hypothesis."...Rutgers spinoff success yields $4.3 million payback to university
... of botanical drug candidates through clinical and preclinical development. It is also engaged in the manufacture of novel therapeutic proteins in plants. To date, Rutgers has received more than $2 million in grant funding from Phytomedics. "The new grant from Phytomedics validates Rutgers' efforts to promote......hio State research as an early preclinical step in making progress toward application of peptide treatment in clinical trials for MS patients. "We are also looking at its applicability in other autoimmune disease, such as in graft ...