Tag: "predisposition" at biology news

Columbia research to examine gene influence on severity of peridontal disease, therapy response

...es targeted specifically to a person's own genetic predisposition for response. A new three-year, $1.8 million grant from the National Institute of Dental & Craniofacial Research will support research to determine whether different forms of periodontitis can be classified based on gene expression in inflamed gums....

Researchers discover why mutant gene causes colon cancer

...the APC gene, as well as an inherited colon cancer predisposition known as familial adenomatous polyposis (FAP) that occurs in people who have APC mutations. In this inherited syndrome, hundreds to thousands of pre-cancerous growths called adenomatous polyps form in the colon, usually beginning before a person is 1...

Humans march to a faster genetic 'drummer' than primates, UC Riverside research says

...fits include making it easier to identifying human predisposition to genetic disease, by comparing humans with other primate species. A third possible benefit is to underline the importance of protecting endangered primate species....

Depression traced to overactive brain circuit

...e families. This added to evidence that a genetic predisposition that renders some people vulnerable to inadequate serotonin activity may be at the root of the mood disorder. The researchers scanned subjects after their blood tryptophan levels were reduced by about three-fourths, using a radioactive tracer (a f...

Researchers identify gene for a primary form of sudden infant death sydrome (SIDS)

...ents answers for sudden infant deaths, recognizing predisposition early, and hopefully saving a number of these babies." The researchers first identified patients with SIDDT in a small Old Order Amish community in central Pennsylvania. Over two generations, nine families from this community had lost twenty-one...

Confidentiality of genetic databases questioned by Stanford researchers

...enetic information will provide early warning of a predisposition to certain diseases or predict how the patient will respond to certain drugs. The relationship between DNA and such traits is usually quite subtle, however, and decoding it may require compiling genetic and medical information from many patients. To ...

OHSU scientists find gene influencing drug withdrawal

...gion of a chromosome known to be associated with a predisposition to physical dependence and withdrawal from sedative-hypnotics like alcohol and barbiturates. During the four-year search, the scientists narrowed the initial field of more than 1,000 candidate genes to only five genes, and finally to one. "We know th...

In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds

...ood intake remains the most critical factor in the predisposition to regain lost weight. This adjustment clearly weighs more on the energy balance equation than the metabolic adjustment on energy expenditure observed in this or any other study. Additionally, the effect that energy intake, or more particularly, carb...

Thimerosal, found in childhood vaccines, can increase the risk of autism-like damage in mice

...reinforces previous studies showing that a genetic predisposition affects risk in combination with certain environmental triggers. The study was conducted by researchers at the Jerome L. and Dawn Greene Infectious Disease Laboratory at the Mailman School of Public Health, Columbia University. Over the past 20 year...

Gene therapy reduces drinking in rats with genetic predisposition to 'alcoholism'

...e technique to cut drinking in rats with a genetic predisposition for heavy alcohol consumption. The findings, along with additional results on the effects of long-term ethanol consumption on certain aspects of brain chemistry, are published in the May 2004 issue of Alcoholism Clinical and Experimental Research. "T...

Something old, something new

...nt cause of aging, developmental abnormalities and predisposition to cancer," explains Dr. Arceci, corresponding aut...igenetic change and chromatin remodeling in cancer predisposition with implications for possible therapeutic targeting."...

Research finds lawn chemicals raise cancer risk in Scottish terriers

... and dog genomes will allow us to find the genetic predisposition toward this form of cancer found in both Scotties ...arity in their genome." Scottish terriers' genetic predisposition toward developing bladder cancer makes them ideal as "sentinel animals" for researchers like Glickma...

Salt-tolerant rice requires careful selection

...ation on silt soils, only varieties with a genetic predisposition for these specific conditions should be used. Manneh carried out field experiments with rice in salt water and in fresh water in The Gambia in West Africa. He also studied the effect of nitrogen fertilisation on the rice yield. The researcher could ...

St. Jude researchers create image of enzyme that orchestrates natural genetic engineering

...me and Werner syndrome, rare disorders linked to a predisposition to develop cancer. White used a modified form of X-ray crystallography to create images of UvsW. In this technique, a crystallized sample of a protein is bombarded with a beam of X-rays. The pattern formed by the diffraction of the beams off the crys...

Annual bioethics forum to explore genetic testing

...abilities to conduct genetic tests for disease and predisposition to disease will be the focus of the Third Annual International Bioethics Forum on April 22-23. The forum - titled "Who Knows? Who Should Know? Welcome to the World of Genetic Testing!" - will be held at Promega Corporation's BioPharmaceutical Technol...

National Foundation For Cancer Research names UCSD's Webster Cavenee NFCR Fellow

... Sciences. His work on the genetic basis of cancer predisposition and progression has been recognized with many honors and awards, most notably the Rhoads Award, and the Charles S. Mott Prize of the General Motors Cancer Research Foundation. Cavenee notes, "It is my honor and pleasure to be associated with the Na...

Common virus may contribute to uncommon bone disease in children

...gest that the virus interacts with some underlying predisposition to the disease," said Dr. Dormans. "We don't know what may cause a predisposition to this disease," continued Dr. Dormans, "but rethinking the cause of LCH may ultimately shift treat...

One-size-fits-all approach to nutrition recommendations may soon be outdated

...cramento, CA January 19, 2004 A person's genetic predisposition to develop heart disease and history of hypertensi... metabolic and genetic make-up, activity level and predisposition to disease. "While the customization trend may sound ideal for those seeking the "perfect" diet, th...

Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3

...she added, this finding supports the theory that a predisposition to alcoholism may be inherited as a general state ... 'predisposition.' It has been theorized that the predisposition for alcoholism may be a brain state in which the brain circuits are overactive. Alcohol may have th...

Alcohol-dependence gene identified

...buse and dependence supports a current theory that predisposition to alcoholism might be inherited as part of a general state of brain overactivation. People at risk for alcoholism may inherit a variety of genes that contribute to this state. Perhaps alcohol normalizes that state of excitability, leading people wit...

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